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Last Updated: 29 Jun 2026

Bioarchitech

Oxford
Founded 2014
Oncolytic virus immunotherapies engineered to destroy solid tumours

Bioarchitech is a preclinical-stage biotechnology company developing oncolytic virus-based immunotherapies for the treatment of common solid tumours.

The company engineers vaccinia virus to encode antibody-like immunotherapy molecules within the viral genome, enabling localised delivery of immune-activating payloads directly within the tumour microenvironment. A second programme uses self-amplifying RNA for intratumoral injection to induce immunogenic cell death prior to surgery.

Both programmes aim to harness the patient's immune system for durable anti-tumour responses.

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