Orfonyx Bio

Orfonyx Bio is a biotechnology company developing genetic medicines that increase, rather than silence, the expression of therapeutic target proteins.

Its platform generates oligonucleotide modulators that act on regulatory elements within the untranslated regions of genes, inhibiting sequence motifs that normally repress protein expression.

This approach is designed to address diseases characterised by insufficient protein expression, broadening the application of oligonucleotide medicine beyond conventional gene-silencing approaches.