Company Directory

Synthetic promoter platform for precision gene expression control

Chromatin Bioscience designs synthetic promoters and gene expression control systems for cell and gene therapy developers. Its platform uses bioinformatics to identify cell-type-selective regulatory elements from the human genome, which are assembled into novel synthetic promoters enabling precise, durable and targeted transgene expression. The company's promoters are integrated into partner programmes across oncology, nephrology and rare disease gene therapies, with a clinical-stage collaboration supporting an in vivo CAR-T candidate for multiple myeloma.

Real-world mental health and dementia data platform for drug development

Akrivia Health is a software company providing a real-world data and AI platform for neuroscience research and drug development. Its dataset of de-identified electronic health records from 6.3 million patients across 20 NHS Trusts covers mental health and dementia conditions, enriched through proprietary natural language processing. Commercial applications include health economics and outcomes research, clinical trial patient recruitment, pharmacovigilance, and drug discovery target identification.

Open biological data resources and bioinformatics services for life sciences

EMBL-EBI is the European Bioinformatics Institute, an intergovernmental research organisation and part of the European Molecular Biology Laboratory (EMBL). Located on the Wellcome Genome Campus in Hinxton, it maintains a suite of freely available molecular biology databases including UniProt, Ensembl, Expression Atlas and the Single Cell Expression Atlas. EMBL-EBI also conducts computational research, delivers bioinformatics training, and operates an industry programme supporting pre-competitive research and translational partnerships.

AI-powered bioinformatics platform for precision oncology and drug discovery

Rayca Precision develops AI and bioinformatics platforms for precision oncology and drug discovery, using transcriptomic data and deep learning to predict drug responses and stratify cancer patients. The company also provides automated multi-omics analysis for preclinical and clinical research workflows, and works with pharmaceutical and biotech partners to design and deliver customised drug candidate libraries, integrating computational modelling with multi-omics profiling across oncology and immunotherapy programmes.

Bioinformatics data platform for biology teams at scale

Goodwright is a London-based software company developing Flow, a web-based bioinformatics platform enabling biology teams to analyse, store, curate, and share genomics data at scale. Built around Nextflow pipeline integration, Flow provides a user-friendly interface for RNA-seq and other omics workflows, linking analysis execution with structured data management and an open database. Developed in collaboration with Professor Jernej Ule's lab at the Francis Crick Institute, Flow serves both academic and commercial research teams.

AI platform predicting complex crop and livestock traits from RNA-Seq data

TraitSeq is an agri-biotech company providing an AI-based platform that predicts complex phenotypic traits in crops and livestock using RNA sequencing data and bespoke machine learning algorithms. The platform identifies transcriptomic biomarkers and builds predictive models for traits such as yield, disease resistance, and climate resilience, enabling agrochemical, biological input, and gene editing companies to evaluate products earlier and reduce field trial dependency. TraitSeq serves breeders, biotechs, and agrochemical researchers across plant and animal applications.

Contract microbial whole genome sequencing and metagenomics service

MicrobesNG Ltd is a UK-based contract sequencing service provider specialising in microbial whole genome and metagenome sequencing. The company processes bacterial, fungal, and viral samples using Illumina short-read and Oxford Nanopore long-read platforms, with DNA extraction and bioinformatics analysis included as standard. Services are accessible to academic, public sector, and commercial customers across more than 40 countries.

Cloud-based informatics platform for drug discovery data management

Collaborative Drug Discovery (CDD) is a software company providing a cloud-based informatics platform for drug discovery research. Its flagship product enables scientists to register compounds, manage bioassay and chemical data, track inventory and capture experiments through an integrated electronic laboratory notebook. The platform supports secure data sharing across distributed teams and external collaborators. CDD Vault is used by pharmaceutical, biotechnology and academic research organisations working across small molecule drug discovery.

Isoform-specific antibody therapeutics for vascular disease

IsomAb is a biotechnology company developing isoform-specific antibody therapeutics for serious vascular diseases. Its lead programme, ISM-001, targets VEGF-A165b, an anti-angiogenic splice isoform implicated in peripheral arterial disease and chronic limb-threatening ischaemia. The company uses a bioinformatics-guided platform to identify pathogenic mRNA splicing targets and develop disease-modifying antibodies for conditions with limited treatment options. ISM-001 is currently in IND-enabling preclinical studies.

Non-profit CRO specialising in clinical trial data and biostatistics

Frontier Science (Scotland) is a not-for-profit contract research organisation providing data management, biostatistics, and quality assurance services for clinical trials. The company works with both academic and commercial sponsors across all phases, with particular strength in large-scale international Phase II and III oncology trials. It is affiliated with Frontier Science Foundation in the United States and Frontier Science in Greece, and has supported landmark breast cancer studies including HERA and OlympiA.

Single-cell omics analysis platform for precision neuroscience research

CellClar is a UK-based Community Interest Company developing an AI-assisted software platform for single-cell omics data analysis in precision medicine. Its flagship product is designed to transform complex single-cell sequencing datasets into actionable insights for researchers working on neurodegenerative diseases, neurological disorders, and brain tumours. The platform aims to consolidate research tools and democratise access to advanced bioinformatics capabilities for scientists globally, with a focus on underserved research communities.

Generative AI platform for whole-organism biological modelling

AI Vivo is an early-stage Cambridge biotechnology company developing a generative AI system that constructs multi-scale biological models linking molecular targets through tissue and organ levels to whole-organism physiology. Its technology integrates multi-modal omics data to simulate disease dynamics and treatment responses, aiming to replace conventional cell-based and animal models in early drug discovery and pharmacology.