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Last Updated: 06/06/2026

Chain Biotechnology

Nottingham
Founded 2014
Engineered live biotherapeutics for oral drug delivery

Chain Biotechnology is a microbiome therapeutics company developing oral live biotherapeutic products using its proprietary platform.

The technology engineers a probiotic Clostridium strain to deliver therapeutic payloads to the lower gastrointestinal tract, where the bacteria produce specific bioactive molecules in situ.

The platform combines mucosal and systemic immune modulation with microbiome enhancement, delivered via stable bacterial endospores requiring no cold chain.

Chain Biotech's pipeline spans infectious disease, inflammatory bowel disease and immuno-oncology applications.