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Last Updated: 09/06/2026
EpilepsyGTx
Cambridge
Founded 2021
AAV gene therapy targeting the seizure focus in refractory epilepsy
EpilepsyGTx is a biotechnology company developing gene therapies for focal refractory epilepsy, a condition in which seizures arise from a specific brain region and do not respond to antiseizure medicines.
Its lead programme, EPY201, is an AAV9-based gene therapy delivered locally via catheter directly to the epileptogenic focus, designed to reduce neuronal hyperexcitability and achieve seizure freedom with a single intervention.
Phase 1/2a clinical trials are planned to commence by the end of 2026.