Genome Therapeutics

Genome Therapeutics is a biotechnology company developing cancer medicines that target G-quadruplex DNA structures associated with tumour biology.

Its approach builds on research into non-canonical DNA folding and how these structures influence gene regulation and cancer cell vulnerabilities. The company develops chemical compounds and antibody-drug conjugate strategies to modulate these targets, aiming for greater tumour selectivity than conventional cytotoxic therapies. Its science originated from research groups in Cambridge and Vancouver.