Discover life science companies across the East of England, including biotechnology firms, CROs, research organisations and innovation hubs.
Next-generation programmable gene insertion platform technology
Gene Weaver is a preclinical-stage biotechnology company developing a programmable, RNA-based gene insertion platform. Its RNA-guided enzymatic system functions as a complete molecular machine, locating the target site and inserting large DNA payloads to enable kilobase-scale gene insertion at virtually any genomic…
Non-viral intracellular delivery platform based on biomolecular condensates
PartitionBio is a biotechnology company developing a non-viral intracellular delivery platform based on liquid-liquid phase separation and biomolecular condensates. Its lead product, BubbleFect, is a room-temperature-stable, non-lipid reagent designed for bench-top use without specialist equipment or cold-chain…
Compact liquid handling automation instruments
Veon Scientific is a UK manufacturer of compact liquid handling automation platforms for R&D laboratories, integrators, and OEM partners. Its instruments offer independent multi-channel pipetting in a bench-top footprint with an open control architecture and configurable deck. Applications include PCR normalisation,…
Near-infrared bioluminescence reagents for preclinical imaging research
Bioflares is a biotechnology company developing and supplying infraluciferin-based reagents and engineered luciferase enzymes for near-infrared bioluminescence imaging. Its patented infraluciferin substrate enables simultaneous dual-parameter imaging of two biological processes in living animals, supporting…
Automated bioreactor platform for cell and gene therapy manufacturing
microfluidX is a UK instruments company developing automated bioprocessing platforms for cell and gene therapy research and manufacturing. Its core product is a microfluidics-based bioreactor system designed for parallel cell culture process development and scalable cell expansion. The platform integrates online…
Drug discovery platform targeting biomolecular condensates
Transition Bio is a biotechnology company developing a drug discovery platform based on the biology of biomolecular condensates, the membrane-less cellular structures implicated in a range of diseases. Using droplet microfluidics and machine learning, the company maps and modulates condensate behaviour to identify…
Rotating wall bioreactors simulating microgravity for cell and crystal research
Microgravity Bioreactors develops rotating-wall laboratory systems that simulate aspects of microgravity on Earth. The vessels keep cells and crystals suspended while limiting sedimentation and shear stress, allowing researchers to explore experimental conditions before committing samples to space-based studies. Its…
World's oldest agricultural research institute studying sustainable farming systems
Rothamsted Research is an agricultural research institute studying crops, soils and sustainable farming systems from gene to field. The institute's work spans crop genetics, gene editing, entomology and agri environmental science, supported by bioscience techniques including proteomics, metabolomics and automated…
Preventing cancer therapy side effects with topical medicines
VasoDynamics is a clinical-stage pharmaceutical development company focused on preventing the debilitating side effects of cancer therapy. The company develops topical formulations targeting radiation-induced oral mucositis, dermatitis, and chemotherapy-induced hair loss, using vasoconstrictor and radioprotective…
Human iPSC platform for neurodegenerative disease drug discovery
Talisman Therapeutics is a drug discovery company specialising in human induced pluripotent stem cell (iPSC) models of neurodegenerative disease. The company operates both an internal discovery pipeline, focused on Alzheimer's disease targets including lysosome biology, pathogenic protein reduction and microglial…
High-sensitivity lateral flow diagnostics for point-of-care testing
SwiftDx is a Cambridge-based diagnostics company developing a next generation of high-sensitivity lateral flow assays using proprietary eAMP (enhanced Amplification) and DNA detection technologies. Its platform enables detection of targets undetectable by conventional lateral flow tests, without requiring specialist…
Fibroblast immunology platform targeting cancer and inflammatory disease
Mestag Therapeutics is a clinical-stage biotechnology company developing first-in-class antibody therapies that target activated fibroblasts to modulate immune responses in cancer and inflammatory disease. Its lead programme, MST-0312, is a FAP-targeted LTBR agonist bispecific antibody designed to induce tertiary…
Microalgae cultivation platform for sustainable transport fuel production
HutanBio is an industrial biotechnology company developing microalgae-derived oils for use in sustainable transport fuels. Its proprietary marine algae strains are grown in enclosed photobioreactors designed for high-salinity, high-temperature environments, enabling cultivation without agricultural land or freshwater.…
Clinical-stage CNS drug discovery using human brain genomics
Cerevance is a clinical-stage biotechnology company developing small molecule therapeutics for neurodegenerative and psychiatric disorders. The company uses its proprietary platform to profile gene expression in specific neuronal and glial cell types from a collection of over 16,000 annotated human brain tissue…
Stem-cell disease models and multi-omics toxicology platforms
Stemnovate is a Cambridge biotechnology company developing human stem-cell models and multi-omics platforms for drug discovery and toxicology. Its induced pluripotent stem cell biobank supports reprogramming, differentiation and the development of disease-relevant cellular models. Genomic, transcriptomic, proteomic…
Human tissue research CRO supporting preclinical drug discovery
Pharmagene Discovery Services is a UK contract research organisation specialising in laboratory-based research services using consented human tissue and primary human cells. The company provides tailored assay design and development across target expression, spatial biology, functional cellular biology, bioassays, and…
Immunomodulatory therapeutics for chronic autoimmune and inflammatory diseases
Kherion Technology is a biotechnology company developing immunomodulatory treatments for chronic autoimmune and inflammatory diseases. Its lead preclinical programme investigates a proprietary therapeutic composition intended to reduce chronic inflammation without broadly suppressing immune activity. A granted US…
Engineered patient cells for sustained therapeutic antibody production
Semper-B Therapeutics is a biotechnology company developing a cell-engineering platform intended to enable patients’ own cells to produce therapeutic antibodies over prolonged periods. The approach aims to achieve durable, precise modulation of immune activity by using engineered cells as a continuing source of…
Real-time cell aggregate monitoring for stem cell manufacturing
MorphoKinetics is a life science instrumentation company developing real-time monitoring technology for stem cell manufacturing. Its process analytical platform combines automated sampling, machine vision and artificial intelligence to measure the size, shape and growth of cell aggregates in bioreactor cultures. The…
Life science and biopharmaceutical park in the Cambridge cluster
Granta Park is a 120-acre managed life science campus in Great Abington, south of Cambridge, owned by BioMed Realty and TWI. The park hosts around 30 organisations across purpose-built laboratory and office facilities, with current tenants including AstraZeneca, Illumina, Gilead, Bicycle Therapeutics and Altos Labs,…