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Last Updated: 08/06/2026

MitoRx Therapeutics

Oxford
Founded 2021
Mitochondrial sulfide-donor therapeutics for obesity and myopathies

MitoRx Therapeutics is a company developing first-in-class small molecule therapeutics that target mitochondrial sulfide signalling, a mechanism implicated in metabolic dysfunction and muscle disease.

Its lead programme is an injectable mitochondria-targeted sulfide donor designed to achieve fat loss without lean mass loss, positioning it as a differentiated alternative to GLP-1 receptor agonists.

Preclinical studies have also demonstrated efficacy in models of Duchenne muscular dystrophy and Alzheimer's disease.

Company Notes