Last Updated: 09/06/2026

Tangram Therapeutics

London

Founded 2001

AI-powered RNAi drug discovery company developing hepatic medicines

Tangram Therapeutics is a biotechnology company combining artificial intelligence and RNA interference to discover and develop novel medicines.

Its proprietary chemistry platform silences disease-driving genes in hepatocytes, and its AI platform drives target identification and siRNA design.

The pipeline includes TGM-312, a first-in-class RNAi medicine for metabolic dysfunction-associated steatohepatitis currently in Phase I/II clinical trials, and TGM-148 for bleeding disorders approaching clinical entry.

Biotech AI & Machine Learning Drug Discovery

Metabolic Disease RNA Therapeutics

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Company Notes

Previously Known As

e-Therapeutics

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