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Last Updated: 05/06/2026

Theolytics

Oxford
Founded 2017
Oncolytic viral therapies engineered for intravenous cancer treatment

Theolytics is a clinical-stage biotechnology company developing oncolytic viral therapies for cancer.

Its phenotypic screening platform enables the discovery and development of adenovirus-based candidates optimised for intravenous delivery and specific patient populations.

The lead programme, THEO-260, entered Phase I/IIa clinical trials in 2024 for platinum-resistant ovarian cancer and is designed to combine direct tumour lysis with immunomodulatory activity.

Additional programmes target colorectal cancer and haematological malignancies.