Drug discovery companies identify, validate and develop new therapeutic candidates for the prevention and treatment of disease. The sector combines biology, chemistry, data science and clinical expertise to bring new medicines from concept to clinic.
This category includes companies working on:
Browse 422 UK drug discovery companies below.
Novel ADC payloads targeting NMT enzymes in cancer
Myricx Bio is a clinical-stage biotechnology company developing a novel class of antibody-drug conjugate payloads based on inhibition of N-myristoyltransferase, an enzyme…
Synthetic VHH antibody libraries and discovery services
Isogenica is a contract discovery company specialising in VHH single-domain antibody discovery, offering what it describes as the world's largest synthetic VHH library alongside…
AI-enabled small molecule drug discovery
PharmEnable is a Cambridge-based drug discovery company developing novel small molecule therapeutics for targets that are inaccessible to biologics, including intracellular…
Clinical-stage anti-infectives targeting antimicrobial resistance and infectious disease
NovaBiotics is a clinical-stage biotechnology company developing first-in-class anti-infective therapies for difficult-to-treat infectious diseases, with a focus on antimicrobial…
Small molecule theranostics to improve transplant outcomes
Kairos Biotech is an early-stage biotechnology company developing proprietary small molecules and nanoscale-engineered binders for application in transplant diagnostics and…
AI-driven natural product discovery for neurological therapeutics
Pangea Bio is a clinical-stage biotechnology company developing small molecule therapeutics for neurological and neuropsychiatric disorders. Its proprietary AI platform screens…
Organ-on-a-chip platforms for pre-clinical drug toxicology research
Revivocell is a biotechnology company developing modular organ-on-a-chip and 3D cell culture platforms for pre-clinical drug discovery and toxicology research. Its platforms…
Computational cell models for novel drug target discovery
Oppilotech is a UK biotechnology company that uses systems biology and machine learning to build high-resolution computational models of cells and bacteria. Its proprietary…
Synthetic aptamer binders as antibody alternatives for research
Aptamer Group is a life sciences company developing synthetic nucleic acid-based affinity binders as high-performance alternatives to antibodies. Selected via its proprietary…
Organ-on-chip devices and preclinical drug testing services
DLOC Biosystems is a biotechnology company developing patented organ-on-chip and human-on-chip technology for preclinical drug testing. Its microfluidic chips enable cells to grow…
Inhaled interferon beta therapy for severe viral lung infections
Synairgen is a clinical-stage biopharmaceutical company developing an inhaled formulation of interferon beta as a broad-spectrum antiviral therapy for severe respiratory viral…
Ion channel drug discovery platform for rare CNS disorders
Autifony Therapeutics is a clinical-stage UK biotech developing small molecule modulators of Kv3 voltage-gated potassium channels for rare genetic CNS disorders. Lead programmes…