UK Life Sciences Company Directory

Targeted small-molecule drugs for brain and metastatic cancers

Sentinel Oncology is a biotechnology company developing targeted small-molecule drugs for difficult-to-treat cancers. Its medicinal chemistry programmes investigate DNA damage responses and cell division. Some candidates are designed to cross the blood-brain barrier, targeting primary brain tumours and cancers that…

Colorimetric assay kits for extracellular matrix analysis and quantification

Biocolor is a Northern Ireland manufacturer of dye-based, colorimetric assay kits for the quantitative analysis of extracellular matrix biomolecules. Its product range covers collagen, elastin, sulfated glycosaminoglycans, proteoglycans, hyaluronic acid, and apoptosis, using a simple dye-binding method compatible with…

Engineered bacterial immunotherapies for solid tumours

Prokarium is a clinical-stage biopharmaceutical company developing microbial immunotherapies using engineered Salmonella strains. Its platform combines synthetic biology with AI-enabled discovery to create programmable bacterial therapeutics that deliver payloads within the tumour microenvironment. The lead programme…

Programmable iPSC cell therapies for cancer and autoimmunity

Xap Therapeutics is a Cambridge-based biotechnology company developing a synthetic biology platform for next-generation cell therapeutics. The company applies CRISPR technology to engineer induced pluripotent stem cells (iPSCs) into a universal "chassis" cell that can be functionalised with engineered receptors and…

Novel mRNA technology platform for safer, faster vaccines

CamMed Therapeutics (Cambridge Medixine Ltd) is a preclinical biotechnology company developing a novel mRNA technology platform for vaccines and therapeutics. Inspired by natural biological phenomena, its engineered RNA molecules are designed to deliver safer, easier and faster medicines to the clinic while reducing…

In vitro biology CRO for immunology and oncology drug discovery

BioMedha is a pre-clinical contract research organisation specialising in in vitro biology for early-stage drug discovery. The company provides assay development, target validation, compound screening, and mechanism of action studies across immunology, oncology, immuno-oncology, and inflammation therapeutic areas.…

Single-workflow sequencing technology capturing genetic and epigenetic data

biomodal is a Cambridge-based life sciences technology company developing multiomics sequencing solutions that simultaneously capture genetic and epigenetic information from a single DNA sample. Its multiomics platform detects the canonical four DNA bases alongside 5-methylcytosine and 5-hydroxymethylcytosine…

AI-driven AAV capsid engineering for next-generation gene therapy

Lir Therapeutics is an early-stage biotechnology company redesigning adeno-associated virus capsids for gene therapy using an AI-first platform. Its platform integrates high-throughput experimental data generation with machine learning models trained on structural, functional and immunogenicity representations of…

Microgravity-based CDMO platform for crystallisation of biologic drugs

BioOrbit is a biotech developing a proprietary hardware platform for the crystallisation of protein-based biologic drugs in low Earth orbit. The company exploits the absence of gravity-driven convection in microgravity to produce larger, more uniform protein crystals than ground-based methods allow, enabling…

Synthetic glucose-binding molecules for continuous glucose monitoring

Carbometrics Limited is a supramolecular chemistry biotech developing synthetic Glucose Binding Molecules (GBMs) for use in continuous glucose monitoring sensors and other diagnostic applications. The GBM platform uses a precisely engineered small-molecule scaffold to selectively bind glucose with high affinity and…

Chemical reagents and contract manufacturing for pharma and diagnostics supply chains

Biosynth Limited is the UK manufacturing and research entity of Biosynth, a global life sciences reagents and contract development and manufacturing organisation. Its Compton, Berkshire site specialises in complex chemical synthesis including carbohydrates, nucleosides, and enzyme substrates, supplying critical raw…

Synthetic glycan-targeted small molecules for next-generation immunotherapy

Anomer Bio is a biotechnology company developing synthetic monosaccharides and small molecule drugs that target glycans, the sugars coating cell surfaces that influence immune responses and disease. Its platform combines multi-omics data and machine learning to model how cells process sugars, enabling the design of…

Engineered biological systems for selective rare-earth metal recovery

LanthaGen Bio is an industrial biotechnology company developing biological systems to recover rare-earth metals from complex material streams. It combines engineered metal-binding proteins with selective separation processes to capture lanthanides from sources such as electronic waste. Its approach aims to concentrate…

Continuous industrial biocatalysis reactors and enzyme automation

Biozeroc is a Cambridge industrial biotechnology company developing continuous biocatalysis systems for large-scale manufacturing. Its technology combines enzyme immobilisation, reactor hardware and automation to maintain consistent output as enzyme activity declines, allowing industrial enzymes to operate for longer…

Bioinformatics, software and compliance consultancy for biotech companies

Prismea is a provider of bioinformatics, software and cloud consultancy services for biotechnology companies. The company supports biotech clients with data analysis across genomics, imaging, spectroscopy, epidemiology and metabolomics, alongside custom software development, cloud infrastructure management and…

CRISPR genome editing and engineered cell models for research

Prime.io is a contract research organisation providing genome editing services and reagents for drug discovery and functional genomics. Its work includes CRISPR knock-in and knock-out cell line generation, gene editing design, pooled screening and sequencing-based validation. The company develops engineered cellular…

Organ-specific liquid biopsy tests for early cancer detection

Mursla Bio is a diagnostics company developing blood-based tests for early cancer detection using extracellular vesicle biology. Its platform isolates organ-specific extracellular vesicles from blood and applies multi-omics profiling and machine learning to identify disease biomarkers without tissue biopsy. Its lead…

Microbial biosynthetic pathways for novel biocatalysts and chemicals

ErebaGen is an industrial biotechnology company using engineered microorganisms to discover enzymes and chemistry from specialised microbial metabolism. Its platform activates normally silent biosynthetic gene clusters, combining computational pathway prediction, genetic engineering and high-throughput…

Bio-inspired adhesion peptides for medical and industrial use

Zentraxa is a biomaterials company engineering bio-inspired adhesion peptides using a proprietary synthetic peptide manufacturing platform. Inspired by marine mollusc chemistry, the platform designs and produces novel peptides with exceptional adhesion properties in wet and submerged environments. Medical applications…

Genome-editing platform mapping cancer drug resistance and druggable vulnerabilities

BASE Rx is a Wellcome Sanger Institute spin-out applying genome-editing and DNA sequencing technologies to cancer drug discovery. The company maps single-base genetic variants to identify druggable vulnerabilities in cancer genes and predict the DNA changes that drive resistance to cancer therapies. BASE Rx aims to…