Back to Directory
Last Updated: 06/05/2026
4basebio
Cambridge
Founded 2019
GMP-grade cell-free synthetic DNA for genetic medicines
4basebio is a biotechnology manufacturing company producing GMP-grade synthetic DNA for use in cell and gene therapies, mRNA vaccines and genome editing applications.
Using an enzymatic, cell-free synthesis process, the company manufactures application-specific linear DNA constructs that overcome the purity and scalability limitations of conventional plasmid-based systems.
4basebio holds MHRA GMP certification for clinical-grade manufacture and also develops non-viral nanoparticle delivery systems for genetic medicine applications.