RNA manufacturing organisations produce RNA materials and provide technologies and services for research, diagnostics, vaccines and therapeutic development. Capabilities range from custom oligonucleotide synthesis and in vitro transcription to purification, formulation, process development and GMP manufacture for clinical applications.
This category includes organisations working on:
Browse 25 UK RNA manufacturing companies, service providers and technology developers below.
Global viral vector CDMO for cell and gene therapy
Oxford Biomedica (OXB) is a global contract development and manufacturing organisation specialising in viral vectors for cell and gene therapy. The company provides lentiviral, adeno-associated virus (AAV), and adenoviral vector development and manufacturing services from early-stage process development through to…
Automated instruments and consumables for cytogenetic and genomic laboratories
ADS Biotec develops and manufactures automated laboratory instruments and consumables for cytogenetic, pathology, and molecular biology applications. Its product range includes robotic systems for chromosome harvesting and spreading, HPLC columns for mRNA purification, and custom buffer and reagent manufacturing…
Custom oligonucleotide synthesis and molecular biology reagent supplier
Willowfort is a UK supplier of custom DNA, RNA and BNA oligonucleotide synthesis services, alongside a broader catalogue of molecular biology reagents and kits for extraction, PCR and qPCR applications. Oligonucleotides are synthesised using phosphoramidite chemistry and purified to order, with quality control by mass…
Modular automated RNA manufacturing platform
Centillion is a UK biotech company whose platform integrates synthesis, purification, and formulation stages using continuous flow chemistry to produce mRNA and self-amplifying RNA at research and production scale. The platform supports process development through to regulatory-ready CMC packages and is available as a…
Next-generation lipid nanoparticle platform for RNA vaccines and medicines
NeoVac is a biotechnology company developing a next-generation lipid nanoparticle platform to improve the delivery of RNA vaccines and therapeutics. Its library of fully biodegradable, tissue-targeted LNPs addresses limitations of first-generation formulations, offering enhanced thermostability, multiple routes of…
Specialty chemical building blocks and reagents for drug discovery research
Fluorochem is a UK manufacturer and supplier of specialty chemicals, reagents and biochemical building blocks, with a catalogue spanning several hundred thousand products used across chemistry, pharmaceuticals and medicinal chemistry research. The company's offering includes ADC linkers, PROTACs, bioconjugation tools…
Developing cell-free long-DNA manufacturing for precision breeding
Newcleic develops cell-free methods for manufacturing long DNA sequences, drawing on biochemical engineering research at UCL. Its technology aims to make complex DNA production more reliable, accessible and sustainable. Its initial focus is agricultural biotechnology, supporting precision breeding and plant…
GMP-grade cell-free synthetic DNA for genetic medicines
4basebio is a biotechnology manufacturing company producing GMP-grade synthetic DNA for use in cell and gene therapies, mRNA vaccines and genome editing applications. Using an enzymatic, cell-free synthesis process, the company manufactures application-specific linear DNA constructs that overcome the purity and…
Integrated chemistry and development CRO for small molecules
CatSci is a Cardiff-headquartered contract research organisation providing integrated chemistry, analytical, and development services to biotech and pharmaceutical companies. Founded in 2010 by former AstraZeneca scientists, the company offers process chemistry, analytical development, solid-state and preformulation…
Custom modified oligonucleotides for research and therapeutics
ATDBio is a University of Southampton spin-out specialising in custom DNA and RNA oligonucleotide synthesis for research, diagnostics and therapeutic development. Its Southampton-based operations supply standard and chemically modified oligos, including antisense sequences, siRNA, aptamers and labelled probes, using…
Enzymatic DNA synthesis for pharmaceutical and biotechnology research
Camena Bioscience is a synthetic biology company that develops and supplies enzymatic gene synthesis technology to pharmaceutical and biotechnology customers. Its multi-enzymatic approach to DNA synthesis offers substantially improved accuracy and access to longer, more complex sequences compared to conventional…
Gene therapy and biologics CDMO with cGMP manufacturing in Liverpool
Pharmaron Biologics (UK) Ltd is a contract development and manufacturing organisation specialising in biologics and cell and gene therapy, operating from cGMP biomanufacturing facilities in Speke, Liverpool. The site offers end-to-end services spanning plasmid design, cell line development, viral vector process…
Circular RNA therapeutics and scalable RNA production
RNAvate is a Cambridge biotechnology spinout developing circular RNA (circRNA) technologies for RNA medicines, founded from research at the MRC Laboratory of Molecular Biology. Its platform focuses on scalable circRNA synthesis and purification to support durable therapeutic protein expression. Published laboratory…
Integrated bioprocessing platform for biologics development and manufacture
Biologic Technologies is a developer of intelligent bioprocessing platforms for biologics development and manufacturing. Its platform integrates complete biological workflows into a single automated device, combining precision fluid handling, in-line process analytics, and AI-driven optimisation. Application-specific…
mRNA vaccine manufacturer and R&D partner
Moderna is a company developing and manufacturing mRNA-based medicines and vaccines across infectious disease, oncology and rare disease. Its UK Innovation and Technology Centre, opened at Harwell in September 2025, is the first facility in the UK capable of onshore mRNA vaccine manufacturing, with capacity for up to…
European hub for RNAi therapeutics developer
Alnylam UK is the European operational headquarters of Alnylam Pharmaceuticals, the pioneer of RNA interference therapeutics. Based in Maidenhead, the UK office serves as Alnylam's primary base for European commercial operations, medical affairs, and regulatory activities. Alnylam has six approved RNAi medicines on…
Technology innovation centre for process scale-up and manufacturing
CPI is a UK innovation centre and social enterprise that helps companies develop, scale and commercialise new products and processes across pharmaceuticals, bioprocessing, health technology and sustainable manufacturing. As a founding member of the High Value Manufacturing Catapult, CPI provides access to specialist…
Separation, purification, and sample preparation tools for life science workflows
Biotage GB is the UK subsidiary of Biotage AB, a Swedish life science tools group with manufacturing roots in Wales dating to 1969. Operating from facilities in Ystrad Mynach and Cardiff, the company designs and manufactures flash purification instruments and columns, solid phase extraction cartridges, and automated…
Contract genomics services including Sanger and next-generation sequencing
GENEWIZ is a genomics services company and providing Sanger sequencing, next-generation sequencing, gene synthesis, oligo synthesis and bioinformatics services to pharmaceutical, biotechnology and academic customers worldwide. Its services span whole genome sequencing, RNA-seq, single-cell sequencing, metagenomics and…
Cell-based platform for next-generation mRNA medicines
Sensible Biotechnologies is a biotechnology company developing a cell-based platform for the design, optimisation, and manufacturing of high-quality mRNA. Using engineered living cells and precision fermentation, the platform produces low-immunogenicity mRNA at scale, addressing fundamental limitations of conventional…