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Last Updated: 08/06/2026

Amphista Therapeutics

Cambridge
Founded 2017
Next-generation targeted protein degradation therapeutics

Amphista Therapeutics is a Cambridge-based biopharmaceutical company developing next-generation targeted protein degradation medicines.

Its proprietary platform generates bifunctional small molecule degraders that harness a broader range of the cell's protein-degrading machinery than existing approaches, enabling improved CNS penetration and wider target scope.

Lead programmes target oncology indications including acute myeloid leukaemia, with neurodegenerative diseases as a second therapeutic pillar.