Protein engineering companies design and modify proteins to improve their activity, stability, selectivity and suitability for specific applications. These technologies support therapeutic development, industrial biotechnology, diagnostics and the creation of improved enzymes and research tools.
This category includes companies working on:
Browse 98 UK protein engineering companies below.
Recombinant and native protein products for life science research
Creative BioMart is a biotechnology supplier of recombinant and native protein products for the research, diagnostics and biopharmaceutical communities. The company offers over 100,000 products, including cytokines, antibodies, antigens and cell and tissue lysates, alongside custom services such as protein expression,…
Non-viral intracellular delivery platform based on biomolecular condensates
PartitionBio is a biotechnology company developing a non-viral intracellular delivery platform based on liquid-liquid phase separation and biomolecular condensates. Its lead product, BubbleFect, is a room-temperature-stable, non-lipid reagent designed for bench-top use without specialist equipment or cold-chain…
Near-infrared bioluminescence reagents for preclinical imaging research
Bioflares is a biotechnology company developing and supplying infraluciferin-based reagents and engineered luciferase enzymes for near-infrared bioluminescence imaging. Its patented infraluciferin substrate enables simultaneous dual-parameter imaging of two biological processes in living animals, supporting…
Biodiversity-derived protein data and AI models for biological design
Basecamp Research is a London-based biotech company that collects biological samples from extreme environments across more than 26 countries, building a proprietary metagenomic database of over ten billion novel protein sequences from more than one million previously unrecorded species. This dataset trains large AI…
Generative AI platform for TCR therapy design and immune repertoire analysis
Synteny Biotechnology is a biotechnology company developing a platform that combines high-throughput TCR-antigen data generation with generative AI to design precision T cell receptor therapies for cancer. The platform addresses a critical bottleneck in the field, namely the scarcity of paired TCR-epitope interaction…
AI-designed protein fibres as sustainable alternatives to synthetic textiles
Solena Materials is an industrial biotechnology company developing a new class of protein-based fibres for the fashion and performance apparel sectors. Using proprietary deep learning models and computational protein design, the company engineers novel proteins from first principles, which are then produced using…
Infectious disease antigens and antibodies for diagnostics and research
The Native Antigen Company is a manufacturer of native and recombinant antigens, antibodies, and immunoassays for viral and bacterial infectious disease targets. Products are supplied to IVD manufacturers, pharmaceutical companies, and academic institutions for use in immunoassay development, serology, vaccine…
Engineered cell-derived vesicles for targeted RNA and drug delivery
AAB Therapeutics develops programmable nanovesicles from engineered human cell membranes for targeted intracellular drug delivery. The vesicles are designed to carry RNA, small molecules or biologics, using surface targeting molecules and fusogenic proteins to release their cargo into cells. The preclinical company…
ECM-targeted drug discovery platform for fibrosis and solid tumours
Engitix is a preclinical-stage biotechnology company developing therapeutics that target the extracellular matrix (ECM) in fibrosis and solid tumours. Its proprietary discovery platform integrates one of the largest ECM bioarchives with AI and machine learning to identify disease-specific targets and biomarkers.…
Programmable cell-killing particle platform for targeted therapeutic delivery
Granza Bio is a biotechnology company developing a cell-targeted delivery platform based on supramolecular attack particles, naturally occurring structures used by cytotoxic T cells and natural killer cells to deliver lethal payloads with precision. The company is engineering programmable versions of these particles,…
Molecular modelling and cheminformatics software for drug discovery
Chemical Computing Group is a scientific software company developing molecular modelling and cheminformatics tools for drug discovery. Its flagship software supports structure-based design, molecular docking, pharmacophore screening and simulations involving small molecules, peptides and proteins. Researchers use…
Bio-inspired adhesion peptides for medical and industrial use
Zentraxa is a biomaterials company engineering bio-inspired adhesion peptides using a proprietary synthetic peptide manufacturing platform. Inspired by marine mollusc chemistry, the platform designs and produces novel peptides with exceptional adhesion properties in wet and submerged environments. Medical applications…
Microgravity-based CDMO platform for crystallisation of biologic drugs
BioOrbit is a biotech developing a proprietary hardware platform for the crystallisation of protein-based biologic drugs in low Earth orbit. The company exploits the absence of gravity-driven convection in microgravity to produce larger, more uniform protein crystals than ground-based methods allow, enabling…
Enzymatic wound debridement therapy derived from maggot biology
SolasCure is a biotechnology company developing a recombinant enzyme-based hydrogel for the treatment of chronic wounds. The lead product contains a protease cloned from medical maggots that degrades non-viable wound tissue including fibrin, elastin, and collagen to prepare the wound bed for healing. The product is in…
Engineered enzymes for recycling plastics and mixed textiles
Evoralis is a biotechnology company developing enzymes that break down plastics such as polyester, nylon and polyurethane into their chemical building blocks for recycling. The company uses a microfluidic screening platform to test large numbers of enzyme variants rapidly, allowing candidates to be discovered and…
Directed evolution platform engineering microbes for industrial biomanufacturing
Evolutor is a biotechnology company developing directed evolution technologies to enhance microbial performance for industrial biomanufacturing. Its proprietary genetic toolbox links bacterial cell fitness to recombinant protein production rates, generating evolved production strains with substantially improved…
AI platform generating novel therapeutic proteins for biotech partners
Latent Labs is a UK-based developer of artificial intelligence models that generate entirely new therapeutic proteins not found in nature. Building on foundational AI protein-structure research, the company's platform designs proteins tailored to specific biological functions, aiming to expand the range of diseases…
Benchtop platform for rapid cell-free protein expression and screening
Nuclera is a Cambridge-based biotechnology company developing benchtop systems for rapid protein expression and screening. Its discovery platform integrates cell-free protein synthesis, digital microfluidics, and automated construct screening to deliver soluble, active proteins in under 48 hours. The system is…
Speciality enzyme discovery, development, and commercial-scale manufacture
Biocatalysts is a Welsh industrial biotechnology company specialising in the discovery, development, and commercial-scale manufacture of speciality enzymes. Operating from fermentation and downstream processing facilities in Nantgarw, the company serves food and beverage, pharmaceutical, and life science industries…
Microbial biosynthetic pathways for novel biocatalysts and chemicals
ErebaGen is an industrial biotechnology company using engineered microorganisms to discover enzymes and chemistry from specialised microbial metabolism. Its platform activates normally silent biosynthetic gene clusters, combining computational pathway prediction, genetic engineering and high-throughput…