Protein engineering companies design and modify proteins to improve their activity, stability, selectivity and suitability for specific applications. These technologies support therapeutic development, industrial biotechnology, diagnostics and the creation of improved enzymes and research tools.
This category includes companies working on:
Browse 98 UK protein engineering companies below.
Recombinant research proteins through innovative bioprocess engineering
Zeus Biologics is a biotechnology startup developing innovative bioprocess engineering approaches to reduce the cost of recombinant protein production for the research community. Founded by a former AstraZeneca biopharmaceutical development scientist, the company applies quality-by-design principles to biologics…
National institute developing new imaging and technology platforms for life science
The Rosalind Franklin Institute is a national institute developing new technologies for the life sciences, bringing together physical sciences, engineering and biology. The Institute's research spans artificial intelligence, biological mass spectrometry, advanced imaging and structural biology, aiming to reveal…
Biophysical platform revealing molecular behaviour for discovery
Apoha is a deep tech company developing a biophysical measurement platform based on nonlinear acoustic wave propagation at liquid interfaces. The platform generates multi-dimensional data on molecular behaviour including responses to stress, motion, and mixture conditions, from small sample volumes. Apoha positions…
Open-source AI models for biomolecular structure and drug design
Boltz is a software and AI company building biomolecular foundation models for drug discovery. Its models predict the three-dimensional structures of proteins and other biomolecules, estimate how strongly small molecules bind their targets, and generate candidate molecules and proteins. Boltz makes models available…
TCR-based bispecific therapeutics for cancer and autoimmune disease
T-Therapeutics is a biotechnology company developing T cell receptor-based therapeutics for cancer and autoimmune disease. Using a humanised TCR mouse platform to generate high-affinity, antigen-specific human T cell receptors, the company engineers bispecific molecules that redirect a patient's own T cells to…
Global CDMO for biologics development and manufacture
Lonza is one of the world's largest contract development and manufacturing organisations, providing services across biologics, cell and gene therapy, and small molecules. Its primary UK site in Slough is a multi-product cGMP facility specialising in mammalian biopharmaceutical development and manufacture. The…
Automated drug discovery platform and CRO services
Arctoris is a technology-enabled contract research organisation that provides automated wet-lab biology and data generation services to biotech and pharmaceutical companies. The company operates a fully robotic, cloud-controlled platform covering biochemical, biophysical, cell-based and structural biology assays…
Microbial CRO for natural product discovery and fermentation scale-up
Isomerase is a company providing contract research and development services centred on microbial synthetic biology, with expertise spanning natural product discovery, enzyme engineering, strain bioengineering, and fermentation process development. It serves clients across pharma, biotech, agritech, food and consumer…
Oral delivery platform for biologics targeting inflammatory diseases
Intract Pharma is a biotechnology company developing proprietary formulation platforms for the oral delivery of complex biologics including monoclonal antibodies and proteins. The technology enables precision delivery to the colon for local and systemic immunomodulation, targeting gastrointestinal and systemic…
Shark-derived single-domain antibody biologics for cancer and inflammation
Elasmogen is a biotechnology company developing next-generation therapeutic biologics based on its proprietary soloMER platform, single-domain antibody-like proteins derived from the shark immune system. soloMERs offer advantages over conventional antibodies in size, stability, and tissue penetration. The pipeline…
Proprietary formulation platform enhancing diabetes and cardiometabolic therapies
Arecor Therapeutics is a biopharmaceutical company developing enhanced formulations of existing therapeutic products for diabetes and cardiometabolic diseases. Its proprietary formulation technology improves stability, concentration and delivery profiles for biologics and peptides, supporting both in-house programmes…
Biparatopic PD-1/VEGFR2 antibody for solid tumour oncology
Ottimo Pharma is a clinical-stage biotechnology company developing biparatopic antibody therapeutics for solid tumour cancers. Its lead programme, Jankistomig, is a first-in-class single-agent IgG antibody that simultaneously targets PD-1 for immune checkpoint inhibition and VEGFR2 to suppress tumour angiogenesis. The…
Synthetic gene promoter platform for biologics and cell and gene therapy
SynGenSys is a synthetic biology company developing proprietary libraries of synthetic gene promoters and signal peptides designed to improve the yield, specificity, and reliability of recombinant protein expression. Its computational platform uses bioinformatics and AI to design novel promoters from first principles,…
Ultra-high-throughput biologics discovery platform powered by generative AI
Sortera Bio is a biotechnology company developing an AI-powered platform for the discovery and engineering of biological therapeutics. The Deep Screening platform generates sequence and functional data across hundreds of millions of biologics in a single experiment, producing large-scale training datasets for…
Generative AI platform for T cell receptor and antibody therapeutics
Etcembly is a biotech company using generative AI to discover and engineer T cell receptor and antibody therapeutics. The company's platform applies large language models to TCR sequence data to design candidates with high affinity and selectivity for cancer and autoimmune disease targets. Its lead programme, ETC-101,…
Engineered biological systems for selective rare-earth metal recovery
LanthaGen Bio is an industrial biotechnology company developing biological systems to recover rare-earth metals from complex material streams. It combines engineered metal-binding proteins with selective separation processes to capture lanthanides from sources such as electronic waste. Its approach aims to concentrate…
Protein superglue vaccine platform targeting infectious disease and cancer
SpyBiotech is a clinical-stage biotechnology company developing vaccines using its proprietary protein superglue technology, which enables efficient and stable attachment of antigens to virus-like particle and viral vector delivery platforms. The approach improves immunogenicity and reduces manufacturing complexity…
Finnish pharma company marketing and developing medicines
Orion Pharma (UK) Limited is the UK subsidiary of Orion Corporation, a Finnish pharmaceutical company. The UK entity manages commercial operations for Orion's prescription medicines portfolio across therapy areas including neurology, respiratory disease, oncology and women's health. A biologics R&D centre opened at…