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Last Updated: 06/06/2026

Broken String Biosciences

Cambridge
Founded 2020
NGS-based platform for off-target gene editing detection and characterisation

Broken String Biosciences is a Cambridge-based genomics company developing tools to improve the safety of cell and gene therapies.

Its platform uses next-generation sequencing to map DNA double-strand breaks across the genome, enabling developers to detect and quantify on- and off-target edits generated by gene editing technologies including CRISPR.

The platform supports programmes from discovery through to clinical development and is available as a service and as an early-access in-laboratory solution.