Gene editing companies develop technologies that make targeted changes to DNA sequences within cells and organisms. These tools support biological research, therapeutic development, cell engineering, agriculture and the creation of improved production strains.
This category includes companies working on:
Browse 60 UK gene editing companies below.
Next-generation programmable gene insertion platform technology
Gene Weaver is a preclinical-stage biotechnology company developing a programmable, RNA-based gene insertion platform. Its RNA-guided enzymatic system functions as a complete molecular machine, locating the target site and inserting large DNA payloads to enable kilobase-scale gene insertion at virtually any genomic…
Non-viral intracellular delivery platform based on biomolecular condensates
PartitionBio is a biotechnology company developing a non-viral intracellular delivery platform based on liquid-liquid phase separation and biomolecular condensates. Its lead product, BubbleFect, is a room-temperature-stable, non-lipid reagent designed for bench-top use without specialist equipment or cold-chain…
Biodiversity-derived protein data and AI models for biological design
Basecamp Research is a London-based biotech company that collects biological samples from extreme environments across more than 26 countries, building a proprietary metagenomic database of over ten billion novel protein sequences from more than one million previously unrecorded species. This dataset trains large AI…
World's oldest agricultural research institute studying sustainable farming systems
Rothamsted Research is an agricultural research institute studying crops, soils and sustainable farming systems from gene to field. The institute's work spans crop genetics, gene editing, entomology and agri environmental science, supported by bioscience techniques including proteomics, metabolomics and automated…
Transformative medicines for cystic fibrosis and serious genetic diseases
Vertex Pharmaceuticals is a global biopharmaceutical company with its European R&D headquarters at Milton Park, Oxfordshire, and its international commercial headquarters in London. The Oxford site conducts full-spectrum drug discovery encompassing human genetics, structural biology, and medicinal chemistry, and has…
Synthetic promoter platform for precision gene expression control
Chromatin Bioscience designs synthetic promoters and gene expression control systems for cell and gene therapy developers. Its platform uses bioinformatics to identify cell-type-selective regulatory elements from the human genome, which are assembled into novel synthetic promoters enabling precise, durable and…
AI-driven intron technology to enhance transgene expression
ExpressionEdits is a biotechnology company developing computational tools to improve protein expression from artificial gene constructs. Its Genetic Syntax Engine uses machine learning and biological data to predict optimal intron insertion patterns within transgenes, increasing protein production levels in mammalian…
Enzymatic synthetic DNA manufacture for gene therapy and molecular biology
NunaBio is a specialist DNA synthesis company developing a cell-free enzymatic platform for scalable production of synthetic DNA, including long oligonucleotides, whole genes and DNA fragments. Its technology avoids the plasmid and primer-dependent steps that constrain conventional phosphoramidite chemistry, enabling…
BBSRC-funded national institute for animal biosciences research
The Roslin Institute is a BBSRC-funded national institute for animal biosciences research, part of the University of Edinburgh's Royal (Dick) School of Veterinary Studies. Research is organised around three challenge areas: sustainable farmed animal production, infectious disease detection and prevention, and…
Gene editing platform for disease-resistant, climate-resilient tropical crops
Tropic Biosciences is an agricultural biotechnology company developing gene-edited varieties of tropical crops, including banana, coffee, and rice, with a focus on disease resistance, climate resilience, and yield improvement. Its proprietary platform combines gene editing with RNA interference to redirect a plant's…
National facility for mouse genetics and preclinical disease modelling
The Mary Lyon Centre at MRC Harwell is the UK's national centre for mouse genetics, providing mouse model generation, phenotyping, cryopreservation, and archiving services to academic and industry researchers worldwide. The Centre offers genome engineering using CRISPR and other techniques to create genetically…
Proprietary gene editing tools and strain development services
Forge Genetics is a contract research organisation developing and applying a proprietary gene-editing platform as an alternative to CRISPR-based approaches. The company provides strain development, specialised fermentation including gas fermentation, and metabolite analytics services for pharmaceutical and industrial…
Custom oligonucleotide synthesis and molecular biology reagent supplier
Willowfort is a UK supplier of custom DNA, RNA and BNA oligonucleotide synthesis services, alongside a broader catalogue of molecular biology reagents and kits for extraction, PCR and qPCR applications. Oligonucleotides are synthesised using phosphoramidite chemistry and purified to order, with quality control by mass…
Exosome-delivered gene editing therapies for neurodegenerative diseases
Evox Therapeutics is a biotechnology company developing exosome-based gene editing therapies for rare, genetically driven neurodegenerative diseases. Its proprietary platform uses engineered exosomes to deliver CRISPR-based gene editors across the blood-brain barrier, enabling targeted genetic intervention in the…
Automated single-cell isolation and cloning instruments for cell biology
Iota Sciences is a developer of automated single-cell handling instruments and cell-line engineering services. The company's platform automates single-cell isolation and cloning in nanolitre volumes, supporting monoclonal cell line development with integrated viability monitoring and documentation. GRID Technology…
Gene editing tools, cell lines and genomic reagents for life science research
Horizon Discovery is a Cambridge-based life sciences company supplying gene editing and gene modulation tools, services, and engineered cell lines to pharmaceutical, biotechnology, and academic customers. Its portfolio includes CRISPR and RNAi reagents, isogenic cell line pairs modelling disease-associated mutations,…
Molecular farming platform producing specialty proteins from crop leaves
Kyomei is a biotechnology company developing a molecular farming platform that genetically engineers crop plants to produce high-value specialty proteins in their leaves. The company extracts these proteins from agricultural leaf waste that would otherwise be discarded at harvest. Kyomei's ingredients target food…
Sequencing kits for genome-wide off-target analysis of gene editing
Broken String Biosciences is a genomics company that develops tools for measuring the safety of genome editing. Its platform uses next-generation sequencing to map DNA breaks and editing intermediates across the genome, allowing developers to detect and quantify on-target and off-target edits made by nucleases and…
Neuroactive therapeutics through genetic engineering of fungi and plants
Empyrean Neuroscience is a biopharma company that uses genetic engineering of fungi and plants to develop small molecule therapeutics for neuropsychiatric and neurologic disorders. Using CRISPR/Cas9 and proprietary transformation technologies, the platform enables precise modulation of neuroactive compound production.…
Human iPSC-derived disease models and drug discovery services
Axol Bioscience is a biotechnology company supplying human induced pluripotent stem cell-derived cells and research services for disease modelling and drug discovery. Its portfolio includes neurons, cardiomyocytes, retinal organoids, retinal pigment epithelium and skin cell models, alongside culture media and custom…