Gene editing companies develop technologies that make targeted changes to DNA sequences within cells and organisms. These tools support biological research, therapeutic development, cell engineering, agriculture and the creation of improved production strains.
This category includes companies working on:
Browse 60 UK gene editing companies below.
Genetically engineered insects for sustainable pest and disease vector control
Flyttr is an Oxfordshire-based biotechnology company developing biological solutions for sustainable pest management. Its core technology uses genetically engineered insects carrying a self-limiting gene to suppress populations of disease-transmitting and crop-damaging pests without chemicals or harm to non-target…
Cell and gene therapy supply chain orchestration software
TrakCel is a Welsh software company providing digital orchestration platforms for the management, tracking, and control of cell and gene therapy products across clinical and commercial supply chains. Its flagship platform manages chain of identity and chain of custody for personalised therapies from sample collection…
Precision-programmed human iPSC-derived cells for biomedical research
bit.bio is a Cambridge-based synthetic biology company that programmes human induced pluripotent stem cells into defined, mature cell types for use in pharmaceutical and academic research. Its precision cell programming technology produces consistent, characterised human cells at industrial scale, supporting drug…
Rejuvenation biology company decoding the genomics of cellular ageing reversal
clock.health is a biotechnology company developing therapies to reverse cellular ageing and extend healthspan by decoding the biological programmes that govern cell rejuvenation. Using a proprietary model in which human induced pluripotent stem cells are artificially aged then permitted to self-rejuvenate, the company…
Cell and gene therapy CDMO with clinical and commercial manufacturing
RoslinCT is a CDMO specialising in advanced cell and gene therapies. Operating purpose-built cGMP facilities at Edinburgh BioQuarter and in Hopkinton, Massachusetts, it provides process development, analytical testing, clinical and commercial manufacturing for autologous and allogeneic cell therapies, with particular…
High-capacity viral vector manufacturing platform for gene therapy
Icosphere Biosciences is a biotechnology company developing manufacturing technology for high-capacity gene therapy vectors. Its platform enables scalable, high-yield, contamination-free production of high capacity adenoviral vectors capable of carrying substantially more genetic material than conventional viral…
Causal cellular data and AI models for drug discovery
CellCodex is a biotechnology company that generates causal data from human cells to train predictive models for drug discovery. It programmes stem cells into pure, aged, disease-relevant cell types, perturbs them at genome scale with CRISPR and compounds, and reads the outcome in single cells. The company applies the…
Targeted oncology combination therapies in biomarker-defined cancer populations
Mosaic Therapeutics is a Cambridge biotech developing targeted combination therapies for cancer. Its proprietary platform integrates genome-scale CRISPR screening, high-throughput combination drug testing across over 1,300 patient-derived tumour models, and advanced computational analysis to identify synergistic drug…
Human iPSC models and AI phenomics for drug discovery
Pixl Bio combines human induced pluripotent stem cell (iPSC) models with AI-driven image analysis for drug discovery and safety research. Its portfolio includes liver cells, stellate cells and disease models, alongside CRISPR engineering, high-content Cell Painting and contract studies. These tools help researchers…
Macrophage-targeted therapeutics for oncology, neurological and fibrotic diseases
Macomics is a University of Edinburgh spin-out developing macrophage-targeted medicines across oncology, neurodegenerative, inflammatory and fibrotic diseases. Its ENIGMAC drug discovery platform combines human macrophage and microglia models derived from induced pluripotent stem cells, gene editing and…
Gene therapies targeting the ageing process and age-related disease
Genflow Biosciences is a longevity-focused biotechnology company developing gene therapies designed to slow or halt the biological ageing process and delay age-related disease. Its lead compound uses an adeno-associated viral vector to deliver a centenarian variant of the SIRT6 gene, with a pipeline spanning human and…
Engineering algae to produce carbon-neutral biofuels at scale
Phycobloom is an industrial biotechnology company developing genetically engineered algae strains capable of continuously secreting oil for use in sustainable aviation fuel and plastics. Using synthetic biology and gene editing, the company has engineered algae to capture atmospheric CO2 while producing oil without…
Off-the-shelf cell therapies for cancer and rare diseases
Empyrean Therapeutics develops off-the-shelf cell therapies intended to make treatments for cancer and rare diseases more accessible. Its approach combines gene editing, stem cell programming and precise genetic control to engineer therapeutic cells. The company is developing cell platforms and manufacturing processes…
Engineered therapeutic red blood cells for rare metabolic and other diseases
Scarlet Therapeutics is a biotechnology company developing a platform for generating therapeutic red blood cells (tRBCs). Erythroid cell lines are genetically engineered to produce red blood cells carrying high concentrations of therapeutic proteins, exploiting their natural tissue distribution, 120-day circulating…
AI-guided CRISPR platform developing precision-bred crop varieties
Phytoform Labs is a plant biotechnology company combining artificial intelligence and CRISPR-Cas gene editing to accelerate the development of novel crop traits. Its platform models sequence-to-function relationships across plant genomes to predict beneficial DNA variants, which are implemented as transgene-free…
International centre of excellence in plant science and microbiology
The John Innes Centre is a research institute conducting fundamental, strategic and applied research in plant science and microbiology. The centre studies plant and microbial genetics, genomics and cell biology, applying techniques including CRISPR gene editing to improve crop resilience and food security. It trains…
Engineered bacterial nanosyringes for intracellular protein delivery
NanoSyrinx is a discovery-stage biotechnology company developing a platform for targeted intracellular delivery of protein and peptide therapeutics. Based on naturally occurring bacterial nanomachines, the company's technology is engineered to deliver biological payloads directly to the cytosol of targeted cells…
Genome-editing platform mapping cancer drug resistance and druggable vulnerabilities
BASE Rx is a Wellcome Sanger Institute spin-out applying genome-editing and DNA sequencing technologies to cancer drug discovery. The company maps single-base genetic variants to identify druggable vulnerabilities in cancer genes and predict the DNA changes that drive resistance to cancer therapies. BASE Rx aims to…
CRISPR genome editing and engineered cell models for research
Prime.io is a contract research organisation providing genome editing services and reagents for drug discovery and functional genomics. Its work includes CRISPR knock-in and knock-out cell line generation, gene editing design, pooled screening and sequencing-based validation. The company develops engineered cellular…
Non-CRISPR RNA-guided gene editing and modulation platform
Pencil Biosciences is a gene editing company developing a fully synthetic, RNA-guided genome modulation platform as an alternative to CRISPR-based technologies. The system is modular in design, significantly smaller than Cas-based tools, and intended to enable precise gene knock-ins without DNA cleavage. Primary…