Back to Directory
Last Updated: 03/06/2026

Pencil Biosciences

Manchester
Founded 2018
Non-CRISPR RNA-guided gene editing and modulation platform

Pencil Biosciences is a gene editing company developing a fully synthetic, RNA-guided genome modulation platform as an alternative to CRISPR-based technologies.

The system is modular in design, significantly smaller than Cas-based tools, and intended to enable precise gene knock-ins without DNA cleavage.

Primary applications include therapeutics for rare genetic diseases, oncology, and infectious disease, with secondary applications in diagnostics, agriculture, and cell line engineering.

Company Notes