Ageing and longevity companies develop therapeutics, diagnostics and research technologies focused on the biological processes associated with ageing. Their work aims to extend healthy lifespan, improve later-life health and address diseases linked to ageing.
This category includes companies working on:
Browse 30 UK ageing and longevity companies below.
C. elegans whole-organism platform for preclinical drug and compound screening
Magnitude Biosciences Limited is a contract research organisation providing preclinical drug discovery and compound screening services using Caenorhabditis elegans as a whole-organism model. Its proprietary biophotonics platform enables automated, high-throughput, non-invasive monitoring of health and lifespan metrics…
Single-workflow sequencing technology capturing genetic and epigenetic data
biomodal is a Cambridge-based life sciences technology company developing multiomics sequencing solutions that simultaneously capture genetic and epigenetic information from a single DNA sample. Its multiomics platform detects the canonical four DNA bases alongside 5-methylcytosine and 5-hydroxymethylcytosine…
Small molecules improving ribosomal translation accuracy in ageing cells
Ribogenyx is a biotechnology company developing small-molecule therapies to improve protein synthesis accuracy in ageing cells. Its approach targets translational fidelity, the accuracy with which ribosomes translate messenger RNA into proteins. By reducing production errors, the company aims to preserve protein…
Therapeutics to restore egg quality and improve IVF outcomes
U-Ploid Biotechnologies is an early-stage biotechnology company developing first-in-class therapeutics to address age-related decline in egg quality. Its lead programme targets chromosomal instability in human oocytes which is a primary driver of IVF failure, miscarriage, and congenital disorders in women of advanced…
Topical peptide therapeutics targeting inflammatory skin disease
Carocell Bio is a pre-clinical stage biotechnology company developing proprietary peptide-based therapeutics for inflammatory diseases. Its pipeline centres on topical formulations that inhibit mitogen-activated protein kinase (MAPK/p38), a key regulator of the inflammatory cascade. Lead programmes target atopic…
Research institute studying the biology of ageing and lifelong health
The Babraham Institute is a life sciences research institute studying the biological mechanisms behind ageing, development and lifelong health. Its research spans epigenetics, immunology and cellular signalling, investigating how gene activity, the immune system and intercellular communication shape health outcomes…
Non-invasive skin epigenomics platform for clinical and cosmetic research
Mitra Bio is a contract research organisation providing a non-invasive skin epigenomics platform to pharmaceutical and cosmetic companies conducting clinical trials on dermatological and age-reversal interventions. Using tape-strip skin sampling combined with whole-genome DNA methylation sequencing and bioinformatic…
RNA therapeutics targeting cellular senescence and age-related disease
Senisca is a preclinical-stage biotechnology company developing oligonucleotide and small molecule therapeutics that reverse cellular senescence by restoring RNA splicing factor activity. Its platform targets the molecular mechanisms of cellular ageing and has broad applicability across multiple age-related diseases.…
AI-driven drug discovery targeting necrosis and age-related disease
LinkGevity is a preclinical-stage biotechnology company developing anti-necrotic therapeutics for age-related and degenerative diseases. Founded in 2023 and based at Babraham Research Campus, the company's proprietary Blueprint Theory of Ageing identifies necrosis as a key driver of biological decline, informing its…
API-first diagnostic infrastructure and biomarker services for healthcare companies
Hurdle is a London-based diagnostics-as-a-service company providing end-to-end diagnostic infrastructure to telehealth companies, consumer health brands, pharmaceutical companies, and clinical research organisations. Its platform integrates sample collection kit manufacturing, accredited laboratory networks,…
Human ovarian cell models and multi-omics drug discovery
OvartiX is a Cambridge biotechnology company developing drug-discovery tools and therapeutic programmes for ovarian and reproductive health. Its platform combines human multi-omics datasets, machine learning and engineered two- and three-dimensional ovarian cell models to identify and validate disease targets. Founded…
Single-cell somatic mutation analysis for measuring biological ageing
AgeCurve is a geroscience company developing diagnostics that measure biological ageing at the level of individual cells. Its approach analyses the burden and lineage structure of somatic mutations in single cells, combining genotype with cellular phenotype data through machine learning to estimate how far ageing has…
Platform for controlled, repeatable cellular rejuvenation therapeutics
BioRes is a preclinical biotechnology company developing a platform for controlled, repeatable cellular rejuvenation. The company's approach aims to restore cellular function as a way of addressing the underlying biological causes of age-related decline and disease, rather than treating individual conditions in…
Non-invasive mitochondrial DNA damage testing for skin health research
Skin Life Analytics is a biotechnology company providing PCR-based testing services that quantify mitochondrial DNA damage in skin using non-invasive swab sampling. The technology detects molecular markers of skin ageing, UV damage, and environmental stress before visible signs appear. Services include direct testing…
Rejuvenation biology company decoding the genomics of cellular ageing reversal
clock.health is a biotechnology company developing therapies to reverse cellular ageing and extend healthspan by decoding the biological programmes that govern cell rejuvenation. Using a proprietary model in which human induced pluripotent stem cells are artificially aged then permitted to self-rejuvenate, the company…
Food and gut health bioscience research on Norwich Research Park
Quadram Institute Bioscience is a BBSRC-funded independent research organisation focused on the interactions between food, gut microbiota, and human health. Operating within the Quadram Institute, a partnership with the University of East Anglia, Norfolk and Norwich University Hospitals, and BBSRC, it conducts…
Gene therapies targeting the ageing process and age-related disease
Genflow Biosciences is a longevity-focused biotechnology company developing gene therapies designed to slow or halt the biological ageing process and delay age-related disease. Its lead compound uses an adeno-associated viral vector to deliver a centenarian variant of the SIRT6 gene, with a pipeline spanning human and…
Small molecule regulators of mitochondrial transfer for age related disease
Nascent Therapeutics is a biotechnology company developing small molecule therapies that regulate mitochondrial transfer between cells. The company's discovery platform identifies compounds that promote the uptake of healthy mitochondria into damaged cells, or block cancer cells from taking mitochondria from…
Synthetic plant metabolites for osteoarthritis and age-related disease
AKL Therapeutics is a privately held UK pharmaceutical company developing APPA, a patented oral investigational medicine combining two synthetic plant metabolites that act synergistically to target multiple signalling pathways in osteoarthritis. Animal studies have demonstrated pain reduction and delayed cartilage…
Cell rejuvenation to reverse disease and age-related disability
Altos Labs studies cellular rejuvenation, aiming to restore cell resilience and understand biological processes underlying disease, injury and ageing. Its international research institutes combine experimental biology, computational science and therapeutic development. Research includes cellular reprogramming and…