Ageing and longevity companies develop therapeutics, diagnostics and research technologies focused on the biological processes associated with ageing. Their work aims to extend healthy lifespan, improve later-life health and address diseases linked to ageing.
This category includes companies working on:
Browse 30 UK ageing and longevity companies below.
Autophagy-enhancing small molecule drugs for neurodegeneration and rare disease
Samsara Therapeutics is a drug discovery company developing first-in-class small molecule therapeutics that restore autophagy, the cellular process of degrading and recycling damaged proteins, which declines with age and is dysfunctional in multiple diseases. Its platform identifies and chemically optimises…
Small-molecule drugs targeting cellular ageing and senescence
Five Alarm Bio Limited is a biotechnology company discovering small-molecule therapies for diseases associated with ageing. Its research targets chemical damage that accumulates inside cells, aiming to reinforce protective mechanisms and delay cellular senescence rather than destroy senescent cells. Candidate…
Mitochondrial disease drug discovery subsidiary of Astellas Pharma
Astellas Engineered Small Molecules U.K. is a Cambridge-based drug discovery subsidiary of Astellas Pharma, operating as part of the company's Mitobridge Division alongside its US counterpart Mitobridge Inc. Originally founded as Nanna Therapeutics and acquired by Astellas in 2020, the entity applies a proprietary…
Glycan-based biological age and inflammaging diagnostics
GlycanAge is a biotechnology company that develops and sells diagnostic tests based on IgG glycan biomarkers. Its flagship product analyses glycans from a finger-prick blood sample to determine a customer's biological age, reflecting the degree of chronic inflammation driving immune ageing. Tests are available…
AI-driven isoform sequencing platform for movement disorder and ageing research
Entelo Bio is an Oxford-based biotechnology company developing a proprietary single-cell isoform sequencing and AI platform to decode disease biology in conditions affecting human movement and ageing. Built on research from the University of Oxford's Botnar Institute for Musculoskeletal Sciences, the platform combines…
Epigenetic reprogramming and senolytic therapeutics for cancer and ageing
199 Biotechnologies is a preclinical-stage biotechnology company developing epigenetic reprogramming and senolytic therapies targeting cancer and age-related disease. Its lead programme applies partial cellular reprogramming to modify the behaviour of glioblastoma cells, reducing malignancy and reactivating natural…
Immunotherapies targeting blood cancer precursor conditions before onset
Athernal Bio is a Cambridge-based biotechnology company developing targeted immunotherapies for high-risk clonal haematopoiesis, a widespread blood stem cell mutation condition that significantly increases the risk of acute myeloid leukaemia and other haematological cancers. The company's pipeline comprises three…
Mitochondrial transplantation platform to restore cellular energy and regeneration
Recondria Therapeutics is a developer of a mitochondrial transplantation platform designed to restore cellular energy, accelerate tissue recovery and support regenerative medicine. The company's approach involves isolating healthy mitochondria and delivering them to damaged cells to restore ATP production and cellular…
AI-powered cell simulation platform targeting ageing and age-driven diseases
Shift Bioscience is a biotechnology company developing an AI-powered virtual cell platform to identify novel therapeutic targets for cellular rejuvenation. Its proprietary single-cell ageing clock measures epigenetic age at high throughput, feeding machine learning models that predict gene combinations and small…
National institute researching dementia and neurodegenerative disease across the UK
The UK Dementia Research Institute is the UK's leading national institute dedicated to transforming outcomes for people affected by dementia and neurodegenerative conditions. Its central Hub at University College London coordinates seven research Centres hosted across leading UK universities, working towards new…