Biomarker discovery and validation organisations identify, measure and evaluate biological signals that help researchers understand disease and treatment response. Their services support drug development, patient stratification and translational research, using molecular, cellular, imaging or physiological measurements.
This category includes companies working on:
Browse 48 UK biomarker discovery and validation companies below.
Breath-based volatile organic compound test for multi-cancer detection
SpiraCheck is a biotechnology company developing a non-invasive breath test for the early detection of gastrointestinal cancers. Patients exhale into a collection device; the sample is analysed in the laboratory by mass spectrometry to quantify volatile organic compounds, and a patented algorithm interprets the…
Specialist histology and immunohistochemistry CRO
HistologiX is a GLP and GCP accredited contract research organisation specialising in tissue-based biomarker analysis for the pharmaceutical and biotechnology industries. The company provides histology, immunohistochemistry, immunofluorescence, and digital pathology services across preclinical toxicology, regulatory…
DNA nanorobot platform for nucleic acid detection and bioanalysis
Nanovery is a biotechnology company developing a patented Nucleic Acid Nanorobotics (NANs) platform for enzyme-free detection and quantification of nucleic acid targets. Synthetic DNA nanorobots generate fluorescent signals in response to specific sequences, enabling direct quantification of antisense…
Multi-omic sequencing and genomics services
Source Genomics is a contract genomics laboratory providing multi-omic sequencing and analytical services to pharmaceutical, biotechnology, and academic clients. Services span Sanger sequencing, next-generation sequencing, Oxford Nanopore long-read sequencing, spatial transcriptomics, optical genome mapping, Olink…
Bioanalytical, DMPK and analytical sciences CRO for drug development
Resolian UK is a contract research organisation specialising in bioanalysis, drug metabolism and pharmacokinetics, and analytical sciences services for pharmaceutical and biotechnology clients. Operating from purpose-built laboratories in Fordham, Cambridgeshire and Sandwich, Kent, the company delivers GxP and non-GMP…
Molecular diagnostics, biomarker research and genomic analysis services
BioMarker Solutions is a diagnostics and research services company supporting biomarker discovery, validation and molecular testing. Its activities cover genomic analysis, oncology diagnostics, clinical trial support, digital pathology and laboratory information systems. The group offers NGSuite software for…
AI-powered immune profiling platform for precision medicine
IMU Biosciences is a biotechnology company coupling high-resolution, systems-level immune profiling with proprietary AI analytics to build a detailed atlas of the human immune system across health and disease. Its platform can identify and analyse over 2,000 immune cell subsets from blood samples, generating…
Ultrasensitive proteomics and biomarker assay development CRO
Altheome is a contract research organisation specialising in protein biomarkers and ultrasensitive proteomics for pharmaceutical, biotechnology and academic studies. Its services include custom assay development, biomarker discovery and validation, protocol optimisation and pharmacokinetic or pharmacodynamic analysis.…
Phosphoproteomics platform for kinase activity profiling and precision oncology
Kinomica is a UK precision medicine company developing phosphoproteomics technology for drug discovery and companion diagnostics. Its platform combines LC-MS/MS mass spectrometry with proprietary bioinformatics to measure kinase activity directly from patient samples, enabling drug target identification, monitoring of…
ISO-accredited core technology facility for cell analysis, genomics, and proteomics
Central Biotechnology Services is an ISO 9001:2015 and GCLP-accredited core technology facility within Cardiff University's School of Medicine. It provides fee-for-service access to platforms spanning flow cytometry and cell sorting, genomics and bioinformatics, electron and light microscopy and proteomics and…
Quantitative digital pathology image analysis services for pharma
OracleBio is a contract research organisation specialising in quantitative digital pathology and histopathology image analysis. The company delivers high-precision tissue biomarker quantification services to pharmaceutical and biotechnology clients, supporting pre-clinical and clinical research programmes. Services…
Organ-specific liquid biopsy tests for early cancer detection
Mursla Bio is a diagnostics company developing blood-based tests for early cancer detection using extracellular vesicle biology. Its platform isolates organ-specific extracellular vesicles from blood and applies multi-omics profiling and machine learning to identify disease biomarkers without tissue biopsy. Its lead…
Bioanalytical CRO for drug quantification across development stages
Alderley Analytical is a contract research organisation providing bioanalytical testing services across the drug development continuum, from discovery through preclinical safety studies to clinical trials. The company specialises in mass spectrometry and ligand binding assays for the quantification of small molecules,…
Human proteome microarrays and protein array screening services
Cambridge Protein Arrays supplies human proteome microarrays and specialist screening services for researchers. Its HuProt arrays contain thousands of full-length human proteins, enabling antibody specificity testing, autoantibody profiling and investigations of molecular interactions. Researchers can obtain arrays or…
Multiomics platform for cancer biomarker discovery and diagnostics
Tagomics is a Cambridge-based biotech developing a multiomics platform for disease biomarker discovery and diagnostics. Its platform integrates genomics, epigenomics and fragmentomics with advanced bioinformatics and machine learning to identify disease-associated DNA markers from blood and other biological sources.…
Contactless respiratory monitoring and digital biomarkers for clinical trials
Albus Health is a clinical research technology company developing passive, contactless monitoring for respiratory studies and pharmaceutical trials. Its bedside Albus Home system combines acoustic and other sensors to measure nocturnal cough, breathing and environmental conditions without requiring patients to wear…
Contract pharmaceutical development, manufacturing and diagnostic services
Almac Group is a privately owned contract development and manufacturing organisation providing integrated services across the drug development lifecycle to pharmaceutical and biotechnology clients. Capabilities span API and peptide synthesis, formulation development, GMP clinical and commercial manufacturing, clinical…
AI imaging platform for lung and heart disease clinical trials
Qureight is a technology-driven imaging contract research organisation providing clinical data curation and AI-powered image analysis services to pharmaceutical and biotech companies. Its proprietary platform integrates CT imaging, biomarkers, and clinical metadata from complex respiratory and cardiovascular diseases,…
AI platform for bone marrow morphology analysis
Ground Truth Labs is an Oxford-based computational pathology company applying machine learning and computer vision to decode disease in bone marrow tissue. Its platform quantifies morphological markers including fibrosis, blasts, and plasma cells at slide and cell level, and identifies novel prognostic patterns…
Targeted transcriptomic sequencing services for diagnostics and drug discovery
BioClavis is a genomics R&D and services laboratory leveraging their targeted RNA sequencing platform for high-throughput transcriptomic and biomarker analysis. The platform enables customisable gene expression profiling from crude cell lysates and archival FFPE tissue without nucleic acid purification, making it…