Browse life science companies in Cambridge, home to one of Europe's leading biotechnology and life science ecosystems.
Specialist CRO for ion channel screening and cardiac safety assessment
Metrion Biosciences is a contract research organisation specialising in preclinical ion channel biology, cardiac safety screening, and neuroscience drug discovery services. Founded in 2015 as a spin-out from Xention Limited, Metrion provides automated and manual patch clamp electrophysiology, GLP-compliant hERG…
In vivo nanoparticle screening for genetic medicine delivery
Ride Therapeutics is a joint University of Cambridge and Harvard spin-out developing nanoparticle delivery systems for mRNA and gene-editing medicines. Its Molecular Logistics platform engineers and screens large libraries of non-viral carriers in living systems, measuring tissue and cell-type targeting to train an…
TYK2/JAK1 inhibitor advancing towards Phase 2 psoriasis trials
Sareum is a clinical-stage biotechnology company developing small-molecule kinase inhibitors for autoimmune diseases and cancer. Its lead oral TYK2/JAK1 inhibitor, SDC-1801, completed Phase 1 testing in healthy volunteers and is being prepared for a Phase 2 study in psoriasis. Dosing in its Phase 2-enabling toxicology…
Coronary plaque biomarkers for precision cardiovascular medicine
PlaqueTec develops a catheter-based liquid biopsy system to investigate biological processes driving coronary artery disease. Its device samples blood at sites around coronary plaques, allowing researchers to compare local concentrations of proteins and other molecules. These data feed its BioCarta platform for…
Oral NLRP3 inhibitors for cardiovascular and neurologic inflammation
Rezera, formerly NodThera, is a clinical-stage biotechnology company developing small molecule inhibitors of NLRP3, an inflammasome implicated in chronic inflammatory and neurodegenerative disease. Its lead asset, ruvonoflast, is a brain-penetrant oral inhibitor that has completed Phase II trials and is advancing…
Integrated drug discovery CRO specialising in small molecule programmes
Domainex is a contract research organisation providing integrated drug discovery services to pharmaceutical companies, biotechnology firms, patient foundations and academic institutions. The company offers medicinal and computational chemistry, protein expression, assay development and structural biology, supporting…
Automated liquid handling and sample management instruments
SPT Labtech is a designer and manufacturer of laboratory automation instruments and consumables for liquid handling, sample preparation, and sample management. Its product portfolio includes nanolitre liquid handling systems for drug discovery and genomics workflows, cryo-electron microscopy sample preparation…
Research institute studying the biology of ageing and lifelong health
The Babraham Institute is a life sciences research institute studying the biological mechanisms behind ageing, development and lifelong health. Its research spans epigenetics, immunology and cellular signalling, investigating how gene activity, the immune system and intercellular communication shape health outcomes…
Custom gene synthesis and molecular biology reagents for laboratory research
NBS Biologicals is a UK manufacturer and supplier of reagents, kits, biochemicals and labware for the laboratory research industry, combining its own expanding NBS product range with representation of major international brands. Through its parent company, the business offers custom gene synthesis and oligonucleotide…
Structural chemistry database and software for drug discovery
The Cambridge Crystallographic Data Centre (CCDC) is a non-profit organisation that curates and distributes the Cambridge Structural Database (CSD), the world's repository of experimentally determined small-molecule organic and metal-organic crystal structures, containing over one million entries. Alongside the…
Small molecule MMR inhibitors to enhance tumour immunogenicity
NeoPhore is a UK immuno-oncology company developing first-in-class small molecule inhibitors of the DNA mismatch repair pathway. By transiently blocking MMR, the company's compounds render tumours MMR-deficient and immunogenic, generating neoantigens that stimulate immune responses against cancer. The approach aims to…
AI genomics for drug target discovery
OutSee is a genomics and drug discovery company using proprietary AI technology to identify and validate novel therapeutic targets. Its core platform applies predictive algorithms to large-scale genomic datasets to uncover disease-modulating biological mechanisms, complementing traditional analysis methods. OutSee…
Computational DNA design for durable genetic medicines
Houdini Bio is an early-stage biotechnology company using computational synthetic biology to redesign DNA for improved performance in genetic medicines. The company is developing approaches to enhance the durability and scalability of gene expression, with potential applications across gene therapies and DNA-based…
ENTECH platform for cell perturbation and AI target discovery
Aparna Bio develops technologies for generating biologically relevant cell-perturbation data to support drug target discovery. Its ENTECH platform is being engineered to deliver experimental perturbation reagents into primary human cells and other disease-relevant models, where conventional delivery methods can be…
Semiconductor biochips and instruments for high-throughput DNA synthesis
LinkZill is a semiconductor technology company developing instruments and consumables for high-throughput DNA synthesis and molecular research. Its thin-film transistor (TFT) biochips use electronic control of electrochemical reactions to manufacture oligonucleotide microarrays and DNA pools. The company supplies…
Modular automated RNA manufacturing platform
Centillion is a UK biotech company whose platform integrates synthesis, purification, and formulation stages using continuous flow chemistry to produce mRNA and self-amplifying RNA at research and production scale. The platform supports process development through to regulatory-ready CMC packages and is available as a…
Microcarrier platform enabling adherent cell screening for drug discovery
Semarion is an advanced materials engineering company developing microcarriers for adherent cell assays in drug discovery workflows. Fabricated using microchip-style microfabrication techniques, Semarion develops magnetically steerable cell carriers that enable small colonies of adherent cells to be moved, pooled, and…
Tissue-based endometriosis models for therapeutic target discovery
Cyclana Bio is a biotechnology company developing human tissue-based models to investigate endometriosis and identify therapeutic targets. Its research combines endometrial tissue biopsies and menstrual fluid samples with molecular profiling and three-dimensional disease models, focusing on extracellular matrix…
KnotBody therapeutics for ion channel and GPCR diseases
Maxion Therapeutics is a biotechnology company developing a pipeline of KnotBody therapeutics for diseases driven by ion channel and G protein-coupled receptor dysfunction. The platform combines naturally occurring mini-proteins with antibodies to generate potent, selective and long-acting biologics against target…
Gene editing tools, cell lines and genomic reagents for life science research
Horizon Discovery is a Cambridge-based life sciences company supplying gene editing and gene modulation tools, services, and engineered cell lines to pharmaceutical, biotechnology, and academic customers. Its portfolio includes CRISPR and RNAi reagents, isogenic cell line pairs modelling disease-associated mutations,…