Epigenomics companies study chemical and structural changes that regulate gene activity without altering the underlying DNA sequence. Their technologies support biological research, biomarker discovery, diagnostics and the development of therapies targeting epigenetic mechanisms.
This category includes companies working on:
Browse 28 UK epigenomics companies below.
Small molecule drug discovery targeting rare genetic diseases and oncology
Tay Therapeutics is a drug discovery company developing targeted small molecule therapies for rare genetic diseases and cancer. Its platform uses stop codon read-through technology to restore production of functional proteins disrupted by premature stop codon mutations, with programmes targeting oncology, cystic…
Precision medicines targeting protein isoforms for neuromuscular disease
ISOgenix is a biotechnology company developing precision medicines that target disease-relevant protein isoforms for neuromuscular and neurological conditions. The company's approach focuses on identifying and modulating specific isoforms produced through alternative gene splicing and epigenetic regulation, aiming to…
Single-workflow sequencing technology capturing genetic and epigenetic data
biomodal is a Cambridge-based life sciences technology company developing multiomics sequencing solutions that simultaneously capture genetic and epigenetic information from a single DNA sample. Its multiomics platform detects the canonical four DNA bases alongside 5-methylcytosine and 5-hydroxymethylcytosine…
Research institute studying the biology of ageing and lifelong health
The Babraham Institute is a life sciences research institute studying the biological mechanisms behind ageing, development and lifelong health. Its research spans epigenetics, immunology and cellular signalling, investigating how gene activity, the immune system and intercellular communication shape health outcomes…
Non-invasive skin epigenomics platform for clinical and cosmetic research
Mitra Bio is a contract research organisation providing a non-invasive skin epigenomics platform to pharmaceutical and cosmetic companies conducting clinical trials on dermatological and age-reversal interventions. Using tape-strip skin sampling combined with whole-genome DNA methylation sequencing and bioinformatic…
Gene editing tools, cell lines and genomic reagents for life science research
Horizon Discovery is a Cambridge-based life sciences company supplying gene editing and gene modulation tools, services, and engineered cell lines to pharmaceutical, biotechnology, and academic customers. Its portfolio includes CRISPR and RNAi reagents, isogenic cell line pairs modelling disease-associated mutations,…
Clinical skin microbiome testing and multi-omic ingredient analysis platform
Sequential Skin is a biotechnology company providing non-invasive clinical microbiome testing and multi-omic analysis services to the personal care and pharmaceutical industries. Using patch-based sampling and next-generation sequencing, the company quantifies how ingredients and formulations affect the skin…
Biomedical discovery institute researching the molecular basis of disease
The MRC Laboratory of Medical Sciences is a biomedical discovery research institute studying the molecular and physiological basis of health and disease. Scientists and clinicians collaborate across three core research areas, including epigenetics and stem cell development, genes and metabolism, and quantitative…
API-first diagnostic infrastructure and biomarker services for healthcare companies
Hurdle is a London-based diagnostics-as-a-service company providing end-to-end diagnostic infrastructure to telehealth companies, consumer health brands, pharmaceutical companies, and clinical research organisations. Its platform integrates sample collection kit manufacturing, accredited laboratory networks,…
DNA methylation blood tests for ovarian and pancreatic cancers
GenoME Diagnostics is a biotechnology company developing molecular blood tests for cancer detection and monitoring. Its liquid biopsy platform identifies DNA methylation and fragmentomic biomarkers, combining them into multiplexed droplet digital PCR assays. Its lead test targets ovarian cancer recurrence and…
Next-generation sequencing and genomic analysis services
Novogene (UK) is a genomic services provider operating as the European hub of Novogene Corporation, one of the world's largest sequencing organisations. Based at Cambridge Science Park, the company offers a comprehensive range of next-generation sequencing services including whole genome, exome, RNA, single-cell,…
AI epigenomics platform for neurodegenerative disease detection
Prima Mente is a biotechnology company developing large-scale biological foundation models to understand and detect neurodegenerative disease. The company generates proprietary multi-omic data including whole-epigenome sequencing, and trains transformer-based models on DNA methylation patterns in cell-free DNA to…
Multi-omic sequencing and genomics services
Source Genomics is a contract genomics laboratory providing multi-omic sequencing and analytical services to pharmaceutical, biotechnology, and academic clients. Services span Sanger sequencing, next-generation sequencing, Oxford Nanopore long-read sequencing, spatial transcriptomics, optical genome mapping, Olink…
3D genomics platform for blood-based clinical diagnostics and precision medicine
Oxford BioDynamics develops blood-based diagnostic tests and precision medicine tools using its proprietary 3D genomics platform. The technology analyses chromosome conformation to identify epigenomic biomarkers linked to disease, prognosis and treatment response. Commercial products include tests for immune…
Bioinformatics CRO delivering omics data analysis and interpretation
Fios Genomics is an Edinburgh-based bioinformatics contract research organisation providing data analysis and interpretation services across genomics, transcriptomics, proteomics and metabolomics. Serving pharmaceutical, biotechnology, and academic clients globally, the company specialises in translating complex omics…
3D multi-omics platform for genetically validated drug target discovery
Enhanced Genomics is a biotechnology company developing a proprietary 3D multi-omics platform that maps genome-wide chromatin interactions to identify genetically validated drug targets for common diseases. Using patented technology integrated with a human cell type-specific multi-omics atlas, the platform links…
First-in-class small molecule inhibitors of RNA-modifying enzymes
STORM Therapeutics is a clinical-stage biotechnology company pioneering the field of RNA epigenetics, developing small molecule inhibitors of RNA-modifying enzymes as a new class of cancer treatment. Its lead programme STC-15, a METTL3 inhibitor, was the first RNA-modifying enzyme inhibitor to enter human clinical…
In vivo cell reprogramming therapies for degenerative disease
Mogrify is a biotechnology company developing a novel class of in vivo reprogramming therapies for degenerative diseases. Its proprietary platforms use large-scale transcriptomic and epigenomic network data to predict the transcription factors required to convert mature human cells directly into target therapeutic…
Microplate consumables and instruments for life science laboratories
Porvair Sciences is a manufacturer of microplates, sample preparation consumables, and laboratory instruments for the life science and biotechnology industries. The company produces microplates across multiple formats and materials for applications spanning sample storage, solid phase extraction, cell culture, and…
Targeted therapies against extrachromosomal DNA in cancer
Econic Biosciences is a drug discovery biotech developing therapies that target extrachromosomal DNA, a circular form of DNA found outside normal chromosomes that drives oncogene amplification, tumour evolution, and treatment resistance across multiple cancer types. The company uses AI to identify and characterise…