Explore life science companies operating throughout Greater London, from biotechnology startups to global pharmaceutical organisations.
Engineered immune cells as living delivery vehicles for genetic medicines
Dart Biosciences is a biotechnology company developing a platform that uses engineered immune cells as living delivery vehicles for genetic medicines. By leveraging immune cells' natural ability to localise to disease-relevant tissues, the platform aims to achieve more spatially precise genetic payload transfer with…
Clinical-stage therapeutics for advanced liver disease
Yaqrit is a clinical-stage biotechnology company developing treatments for patients with advanced liver disease, including cirrhosis and acute-on-chronic liver failure. Its pipeline includes an oral ammonia scavenger for hepatic encephalopathy, an extracorporeal liver support device, and a microbiome-based…
Laboratory animal research standards, welfare and 3Rs guidance
Laboratory Animal Science Association is a scientific society supporting professionals involved in animal research and experimental models. It publishes practical guidance on animal welfare, ethical review, behavioural studies and training under UK legislation governing scientific animal use. Its specialist sections…
Gene therapy company targeting complement-mediated ocular diseases
Complement Therapeutics is a clinical-stage biotechnology company developing gene therapies and protein-based therapeutics for diseases driven by dysregulation of the complement immune pathway. A spin-out from the University of Manchester, the company's lead programme CTx001 is an AAV-based gene therapy for geographic…
Xeno nucleic acid binders for targeted drug delivery
Xterna is a biotechnology company developing cell-specific molecular binders composed of xeno nucleic acids (XNAs), chemically modified nucleic acids distinct from naturally occurring DNA and RNA. XNA-based binders are engineered to target cell types that evade conventional antibody-based approaches, enabling drug…
Plant-based biomaterials and compostable leather alternatives
Biophilica is a biomaterials company developing plastic-free alternatives to leather and synthetic adhesives from renewable plant feedstocks. Its Treekind material combines lignocellulosic waste with an algae-derived binder to produce a compostable, leather-like sheet. The company also develops bio-based adhesives and…
Molecular biology reagents and immunological raw materials for diagnostics
Meridian Bioscience's UK operation manufactures and supplies molecular biology reagents and immunological raw materials to diagnostic test developers, pharmaceutical companies, and research institutions worldwide. Products include ultra-pure nucleotides, DNA polymerases, PCR master mixes, purified antigens and…
World's largest independent cancer research funder and charity
Cancer Research UK is a registered charity and the world's largest independent funder of cancer research, supporting over 4,000 researchers, doctors and nurses across the UK. The organisation funds basic laboratory research, drug discovery, clinical trials, prevention and early detection science. It operates four core…
Micellar oral cannabidiol formulation for psychiatric drug development
NWPharmaTech is a clinical-stage biotechnology company developing investigational oral cannabidiol formulations for psychiatric disorders. Its NWPT-SM32300 programme uses a high-loading micellar softgel intended to deliver consistent oral doses. The company reports completion of a Phase 1 pharmacokinetic and…
ECM-targeted drug discovery platform for fibrosis and solid tumours
Engitix is a preclinical-stage biotechnology company developing therapeutics that target the extracellular matrix (ECM) in fibrosis and solid tumours. Its proprietary discovery platform integrates one of the largest ECM bioarchives with AI and machine learning to identify disease-specific targets and biomarkers.…
AAV gene therapy for Bardet-Biedl syndrome and genetic obesity
Axovia Therapeutics is a biotechnology company developing adeno-associated viral gene therapies for inherited ciliopathies and genetic obesity. Its lead candidate delivers a functional BBS1 gene into retinal cells to investigate treatment of vision loss associated with Bardet-Biedl syndrome. A first-in-human, early…
Microgravity-based CDMO platform for crystallisation of biologic drugs
BioOrbit is a biotech developing a proprietary hardware platform for the crystallisation of protein-based biologic drugs in low Earth orbit. The company exploits the absence of gravity-driven convection in microgravity to produce larger, more uniform protein crystals than ground-based methods allow, enabling…
Antibody inhibitors of metzincin proteases for eye disease and cancer
Vasgen develops antibody therapeutics for eye disease and cancer, focusing on enzymes known as metzincin proteases. Its discovery platform uses monoclonal antibodies to inhibit these enzymes selectively, offering a different approach to targets that have proved challenging for conventional small-molecule medicines.…
AI platform generating novel therapeutic proteins for biotech partners
Latent Labs is a UK-based developer of artificial intelligence models that generate entirely new therapeutic proteins not found in nature. Building on foundational AI protein-structure research, the company's platform designs proteins tailored to specific biological functions, aiming to expand the range of diseases…
UK life sciences trade association and membership network
The BioIndustry Association is the UK's trade association for the biotechnology and life sciences sector, representing start-ups, scale-ups, pharmaceutical companies, academic institutions, investors and service providers since 1989. It conducts policy advocacy with government and regulatory bodies, produces sector…
AI-powered infrared diagnostic test for breast cancer recurrence risk
Digistain is a biotechnology company developing MHRA-cleared diagnostic technology for predicting breast cancer recurrence risk. The platform uses infrared spectrometry to generate spectroscopic signatures from tumour biopsy tissue, with AI analysis producing a personalised prognostic score indicating the likelihood…
AAV gene therapy platform targeting podocyte-mediated kidney disease
Purespring Therapeutics is a clinical-stage biotech developing AAV-based gene therapies for chronic kidney disease. Its platform delivers therapeutic transgenes directly to podocytes, specialised cells implicated in the majority of renal diseases, enabling disease-modifying treatment of both rare monogenic and more…
AI-powered rare disease case finding for primary care
Mendelian is a digital health software company developing AI-driven tools to support the earlier diagnosis of rare diseases in primary care. Its core product is a Class 1 regulated medical device that analyses electronic health records to identify patients whose symptom profiles are consistent with published…
Nanopore platform for single-molecule full-length protein sequencing
Portal Biotech is a biotechnology company developing benchtop nanopore instruments for single-molecule proteomics and metabolomics. Its platform uses bioengineered nanopores coupled with machine learning to sequence intact, full-length proteins at the single-molecule level, capturing protein mutations, modifications…
ML-guided strain engineering to optimise precision fermentation yields
Eden Genetics is a biotechnology company using machine learning to improve recombinant protein production through microbial strain engineering. Its computational platform analyses genetic and fermentation data to identify modifications intended to increase protein secretion and productivity in precision-fermentation…