Life Science & Biotech Companies in London

GPCR-targeted small molecule drugs for rare and inflammatory disease

Trio Medicines is a small pharmaceutical company developing small molecule therapeutics targeting G-protein coupled receptors for diseases with unmet clinical need. Its pipeline includes gastrin/CCK2 receptor antagonists for gastric neuroendocrine tumours, a selective β2-adrenoceptor antagonist, and a formyl peptide…

UK trade organisation for international life sciences partnering

BioPartner UK is a UK-accredited trade organisation facilitating international partnering, trade, and investment for life sciences companies across the UK. It leads UK delegations to major international biopartnering conferences and maintains alliances with global partnering event organisers. Its membership programme…

Microfluidic avidity platform for preclinical cell therapy validation

Avigen is a contract research organisation providing preclinical validation services for cellular immunotherapies using a proprietary microfluidic platform. The platform measures cellular avidity, the total binding strength between immune and cancer cells, at high throughput using fluid shear stress, enabling…

AI platform for pharma drug discovery workflows

DaltonTx is a technology company building adaptive AI-enabled discovery platforms for the pharmaceutical industry. Its disease- and modality-agnostic platform integrates into pharma, biotech and CRO workflows, supporting both small molecule and biologics discovery through a self-learning system that improves with…

Clinical-stage oncology company advancing in-licensed cancer drug assets

Ellipses Pharma is a clinical-stage oncology drug development company that in-licenses cancer drug assets from academia and industry, advances them through clinical trials using a continuous funding model, and out-licenses at value-inflection points. Its pipeline spans small molecule kinase inhibitors, selective…

Blood-based CIZ1B biomarker test for early-stage lung cancer detection

Cizzle Biotechnology is a UK-based diagnostics company developing a non-invasive blood test for the early detection of lung cancer. The company's CIZ1B biomarker test identifies a stable plasma biomarker highly correlated with early-stage disease, offering an alternative to imaging or biopsy procedures. Cizzle's test…

3D immune-microtumour platform for cancer treatment selection

Pear Bio is a biotechnology company that tests cancer treatment efficacy directly on patient-derived tumour samples using three-dimensional immune-microtumour cultures and computer vision analysis. By culturing tumour biopsies with matched patient immune cells and imaging drug effects over time, the platform generates…

Clinical whole genome sequencing and reporting platform

StoreGene is a UCL spin-out providing a clinical genomic operating system that integrates whole genome sequencing with automated bioinformatics pipelines and genomic counselling services. Its platform generates clinical reports across cardiovascular genetics, hereditary cancer, pharmacogenomics, and nutrigenetics,…

Clinical-stage precision oncology developing first-in-class TACC3 inhibitor therapeutics

Coiled Therapeutics is a UK-listed, clinical-stage oncology company developing precision cancer therapeutics against structurally complex, previously undruggable targets. Its lead candidate, AO-252, is a first-in-class, orally administered small molecule inhibitor of TACC3 currently in Phase I trials for advanced…

Antigenic immunomodulation therapies targeting autoimmune disease

Phaim Pharma is a biotech company developing disease-modifying therapeutics for autoimmune conditions using its proprietary platform. The platform is designed to reset the immune system by reintroducing disease-specific antigenic epitopes, suppressing the autoaggressive T cell responses that underlie conditions such…

Precision medicine platform for patient recruitment and genetic testing

Sano Genetics is a London-based software company providing an end-to-end platform for patient recruitment, at-home genetic testing, and long-term participant engagement in precision medicine clinical trials and population genomics programmes. The platform integrates DNA testing logistics, medical history retrieval,…

Bio-based polyurethane alternatives from agricultural waste and seaweed

AlGreen is an industrial biotechnology company developing bio-based alternatives to petroleum-derived polyurethanes, which account for approximately 8% of global plastics. Using biotechnology, chemistry, and materials science, the company synthesises fully biodegradable, high-performance polyurethane substitutes from…

Clinical-stage bispecific antibody therapies for cancer and blood disease

NovalGen is a clinical-stage biotechnology company developing multi-specific biologics for oncology, haematological malignancies, and autoimmune diseases. Its proprietary platform embeds a feedback mechanism into therapeutic biologics that deactivates the drug in response to excessive immune activation, aiming to…

UK affiliate of global innovative medicines company Novartis AG

Novartis Pharmaceuticals UK Limited is the UK commercial and medical affiliate of Novartis AG, the Swiss-headquartered global pharmaceutical company. Headquartered at White City Place in London, the UK operation employs approximately 1,300 people and focuses on commercialisation, medical affairs, regulatory…

Multiplexed imaging platform for therapeutic mechanism of action discovery

Micrographia Bio is a biotechnology company developing a spatial proteomics platform for drug discovery. Its technology combines highly multiplexed microscopy with machine-intelligent computer vision to autonomously determine the mechanism of action of therapeutic candidates by visualising protein-protein interactions…

AI-driven precision fermentation for sustainable ingredients

Twig Bio is a bioengineering company using AI and laboratory automation to develop sustainable, bio-fermented alternatives to petrochemical and agriculturally derived ingredients. Its platform combines machine learning-guided pathway design with high-throughput robotic strain building and screening, enabling rapid…

Laboratory automation orchestration software and custom robotic workcells

Lab Donkey is a laboratory automation technology company developing software that coordinates instruments, robots and scientific workflows. Its platform provides device drivers, workflow orchestration, deterministic scheduling, live monitoring and recovery after equipment errors. It also supports guided digital…

AI-driven discovery of fungal natural product therapeutics

Novogaia is a biotechnology company using machine learning and analytical chemistry to discover drug-like molecules from fungi. Its Gaia-01 model predicts molecular structures from mass spectrometry data, enabling researchers to characterise natural compounds and identify chemical starting points for drug discovery.…

Personalised cancer treatment selection using in vivo drug screening

Vivan Therapeutics is a London-based biotech developing a personalised cancer therapeutics platform. The company's Personal Discovery Process sequences a patient's tumour genome, engineers those mutations into a fruit fly avatar model, and screens thousands of approved drug combinations at high throughput to identify…

AI-powered RNAi drug discovery company developing hepatic medicines

Tangram Therapeutics is a biotechnology company combining artificial intelligence and RNA interference to discover and develop novel medicines. Its proprietary chemistry platform silences disease-driving genes in hepatocytes, and its AI platform drives target identification and siRNA design. The pipeline includes…