Nephrology companies develop therapies, diagnostics and research technologies for diseases affecting the kidneys and renal system. Their work supports earlier detection, disease monitoring and the treatment of acute, chronic and inherited kidney conditions.
This category includes companies working on:
Browse 13 UK nephrology and kidney disease companies below.
AAV gene therapy platform targeting podocyte-mediated kidney disease
Purespring Therapeutics is a clinical-stage biotech developing AAV-based gene therapies for chronic kidney disease. Its platform delivers therapeutic transgenes directly to podocytes, specialised cells implicated in the majority of renal diseases, enabling disease-modifying treatment of both rare monogenic and more…
Blood-based liquid biopsy for endothelial glycocalyx and microvascular health
Dimension Biotechnologies is a biotech developing a rapid, blood-based diagnostic for microvascular health based on analysis of the endothelial glycocalyx, the molecular layer lining blood vessel walls whose biochemical integrity is disrupted early in cardiovascular disease, kidney disease, diabetes, and sepsis. The…
AI-driven drug discovery targeting necrosis and age-related disease
LinkGevity is a preclinical-stage biotechnology company developing anti-necrotic therapeutics for age-related and degenerative diseases. Founded in 2023 and based at Babraham Research Campus, the company's proprietary Blueprint Theory of Ageing identifies necrosis as a key driver of biological decline, informing its…
Real-time biosensing to assess donor kidney function in transplantation
Accunea is a medical technology company developing real-time biosensing systems that monitor organ function before and after kidney transplantation. Its bedside platform uses electrochemical sensors and microfluidic cartridges to track established biomarkers of kidney function and metabolism, such as creatinine,…
FDA-approved AI blood test for diabetic kidney disease risk
Renalytix is an artificial intelligence-enabled in vitro diagnostics company focused on the clinical management of chronic kidney disease. Its blood-based test combines biomarker analysis with machine learning to generate a five-year kidney function decline risk score in adults with type 2 diabetes and CKD stages 1 to…
AI-driven delivery platform for siRNA therapies beyond the liver
Undecimal Bio is a biotechnology company developing targeted delivery technologies for small interfering RNA (siRNA) therapeutics beyond the liver. Its DELiveri platform combines large-scale combinatorial chemistry, functional cell-based screening and AI to identify synthetic conjugates that transport siRNA into…
Specialist renal pharmaceuticals and clinical nutrition products
Stanningley Pharma is a specialty pharmaceutical company focused on products for patients with chronic kidney disease and other hospital medicine therapeutic areas. The company licenses, develops, and markets prescription medicines and Foods for Special Medical Purposes into the NHS, including a calcium acetate…
AI-driven precision therapeutics for metabolic syndrome diseases
Multiomic Health is a data-centric therapeutics company developing precision medicines for metabolic syndrome-related conditions, including type 2 diabetes, cardiovascular disease, chronic kidney disease and non-alcoholic fatty liver disease. The company integrates multi-omics data with longitudinal clinical datasets…
Small molecule therapeutics targeting PDE4 enzymes in kidney disease
Mironid is a company developing first-in-class small molecule therapeutics for autosomal dominant polycystic kidney disease, one of the most common hereditary kidney disorders. Its lead programme targets long-form PDE4 enzymes to modulate cyclic AMP signalling, the central driver of cyst growth across all disease…
DUB inhibitor therapeutics targeting mitophagy and degenerative disease
Mission Therapeutics is a clinical-stage biotechnology company developing first-in-class small molecule inhibitors of deubiquitylating enzymes to treat diseases driven by mitochondrial dysfunction. By targeting a mitochondria-localised DUB, the company's drug candidates are designed to enhance mitophagy, the cellular…
Handheld blood-electrolyte monitoring technology for kidney and cardiovascular care
Kalium Health is a medical technology company developing handheld blood-electrolyte monitoring for people with kidney and cardiovascular conditions. Its device is designed to measure potassium and other electrolytes from a single drop of blood using disposable test consumables, supporting monitoring outside…
Engineered macrophage cell therapy for inflammatory and fibrotic disease
Resolution Therapeutics is a clinical-stage biotech developing regenerative macrophage therapies for inflammatory and fibrotic diseases. Its platform harnesses the tissue-repairing properties of macrophages, engineering them to deliver anti-fibrotic and anti-inflammatory effects at sites of organ damage. The lead…
Independent global health research institute focused on chronic diseases
The George Institute for Global Health (UK) is an independent medical research institute conducting large-scale clinical trials, population studies, and health policy research on non-communicable diseases. Based at Imperial College London's White City Campus and affiliated with Imperial as a strategic partner, the UK…