Explore life science & biotech companies in Oxford, home to one of the world's leading biotechnology and life science clusters.
Mitochondrial transplantation platform to restore cellular energy and regeneration
Recondria Therapeutics is a developer of a mitochondrial transplantation platform designed to restore cellular energy, accelerate tissue recovery and support regenerative medicine. The company's approach involves isolating healthy mitochondria and delivering them to damaged cells to restore ATP production and cellular…
TCR therapeutic discovery platform targeting solid tumours
T-Cypher Bio is a pre-clinical biotechnology company developing T-cell receptor therapeutics using its proprietary platform, which integrates immunopeptidomics, bead-display microfluidics, and immune synapse mapping to identify novel intracellular targets and potent TCRs directly from patient tissue. The approach…
Generative AI platform for T cell receptor and antibody therapeutics
Etcembly is a biotech company using generative AI to discover and engineer T cell receptor and antibody therapeutics. The company's platform applies large language models to TCR sequence data to design candidates with high affinity and selectivity for cancer and autoimmune disease targets. Its lead programme, ETC-101,…
Carbon capture and biomanufacturing using engineered cyanobacteria
CyanoCapture is a company developing a biomanufacturing platform that uses genetically engineered cyanobacteria to sequester carbon dioxide and convert it into high-value products including recombinant proteins and graphite. Its photobioreactor-based system is designed to offer affordable carbon capture for industrial…
Multiplex PCR and NGS diagnostics for cancer and infection
GeneFirst is a molecular diagnostics company developing multiplex PCR assays and next-generation sequencing technologies for cancer screening, precision oncology and infectious disease testing. Its Papilloplex assays detect high-risk human papillomavirus DNA or E6/E7 mRNA. The XCeloSeq platform provides library…
University of Oxford GMP facility for clinical-grade biologics
The Clinical BioManufacturing Facility is the University of Oxford's GMP-licensed manufacturing facility, producing biological investigational medicinal products for early-phase clinical trials. The facility holds an MHRA Manufacturer's Authorisation for Investigational Medicinal Products and manufactures viral vector…
Protein superglue vaccine platform targeting infectious disease and cancer
SpyBiotech is a clinical-stage biotechnology company developing vaccines using its proprietary protein superglue technology, which enables efficient and stable attachment of antigens to virus-like particle and viral vector delivery platforms. The approach improves immunogenicity and reduces manufacturing complexity…
Life science reagents and assay technologies distributor
2BScientific is a UK-based distributor of life science reagents, assay kits and research technologies serving academic, clinical and commercial laboratories across the UK and Europe. The company supplies a broad portfolio of molecular biology, immunology and cell biology products from global manufacturing partners,…
Transcription factor-targeting drug discovery for neurodegeneration
Scripta Therapeutics is an Oxford-based biotech company developing disease-modifying therapeutics by mapping and modulating transcription factor networks. Its platform integrates AI, imaging, and patient-derived models in a lab-in-the-loop workflow to identify compounds that restore healthy cellular states. The…
Research reagents, protein analysis instruments and spatial biology technologies
Bio-Techne is a global life sciences company supplying research reagents, analytical instruments and diagnostic technologies through its UK subsidiary. Its portfolio includes recombinant proteins, antibodies, immunoassays, cell culture reagents, automated protein analysis instruments and spatial biology platforms.…
Dark genome platform identifying first-in-class targets for autoimmune disease
Nucleome Therapeutics is a drug discovery company using 3D genome mapping to identify therapeutic targets encoded in the non-coding regions of the human genome. Its platform integrates high-resolution chromatin conformation data with functional genomics and machine learning to link disease-associated genetic variants…
Predictive genetic tests for cancer and cardiovascular disease
GENinCode is a clinical-stage diagnostics company developing polygenic risk assessment tests for cardiovascular disease and ovarian cancer. Its portfolio includes CE-marked molecular tests for coronary artery disease, familial hypercholesterolaemia and thrombosis risk, alongside the ROCA test for ovarian cancer…
Inhaled lentiviral gene therapies for rare respiratory diseases
AlveoGene is a biotechnology company developing inhaled gene therapies for rare respiratory disorders. It uses a lentiviral vector platform engineered to deliver therapeutic genes efficiently to the cells lining the airways and lungs. Its lead programme targets alpha-1 antitrypsin deficiency, an inherited condition…
Quantitative pharmacology and modelling consultancy for drug development
Physiomics is a life science consultancy providing model-informed drug development, quantitative pharmacology, and biostatistics services to biopharma and biotech clients. Services include PK/PD and quantitative systems pharmacology modelling, clinical trial design, biostatistics, and personalised dosing tools. Its…