Explore life science & biotech companies in Oxford, home to one of the world's leading biotechnology and life science clusters.
Computational chemistry and data informatics for drug discovery
NovaData Solutions is a contract research organisation providing computational chemistry, molecular modelling, and data informatics services to pharmaceutical and biotechnology clients. Its capabilities span the early drug discovery workflow, including target validation, hit identification, lead optimisation, and…
Cell-based platform for next-generation mRNA medicines
Sensible Biotechnologies is a biotechnology company developing a cell-based platform for the design, optimisation, and manufacturing of high-quality mRNA. Using engineered living cells and precision fermentation, the platform produces low-immunogenicity mRNA at scale, addressing fundamental limitations of conventional…
Individualised neoantigen-based cell therapies for ovarian and solid cancers
Singula Bio is a seed-stage biotechnology company developing individualised, neoantigen-based cell therapies for patients with solid tumours, with an initial focus on ovarian cancer and other difficult-to-treat malignancies. The company's approach harnesses a patient's own immune system to target mutations that appear…
Oncolytic viral therapies engineered for intravenous cancer treatment
Theolytics is a clinical-stage biotechnology company developing oncolytic viral therapies for cancer. Its phenotypic screening platform enables the discovery and development of adenovirus-based candidates optimised for intravenous delivery and specific patient populations. The lead programme, THEO-260, entered Phase…
AI platform for bone marrow morphology analysis
Ground Truth Labs is an Oxford-based computational pathology company applying machine learning and computer vision to decode disease in bone marrow tissue. Its platform quantifies morphological markers including fibrosis, blasts, and plasma cells at slide and cell level, and identifies novel prognostic patterns…
National institute developing new imaging and technology platforms for life science
The Rosalind Franklin Institute is a national institute developing new technologies for the life sciences, bringing together physical sciences, engineering and biology. The Institute's research spans artificial intelligence, biological mass spectrometry, advanced imaging and structural biology, aiming to reveal…
ML platform designing optimised CAR-T and BiTE therapies
Coding Bio is a biotechnology company using machine learning and high-throughput screening to design chimeric antigen receptor and bispecific T cell engager therapies. The company's platform screens millions of modular protein candidates in living cells to identify designs that best induce immune responses, generating…
AI-driven tRNA synthetase platform for novel small molecule therapeutics
Oxford Drug Design is an Oxford biotech developing small molecule therapeutics using an integrated platform combining aminoacyl-tRNA synthetase biology with proprietary generative AI and machine learning. The platform provides structural biology knowledge, crystallographic data, and novel chemotypes targeting tRNA…
AI-driven platform engineering better crop varieties
Wild Bioscience is an agricultural biotechnology company developing next-generation crop varieties using a platform that combines evolutionary biology with machine learning. By mining genetic variation in wild plant relatives, the company identifies and designs gene edits targeting traits including nitrogen use…
UK life sciences membership network and biopartnering organisation
BioUK (Previously OBN) is a not-for-profit membership organisation supporting the UK life sciences sector. With over 450 member companies spanning emerging biotechs, established pharma, investors, science parks, and professional services organisations, BioUK's membership is concentrated in the Golden Triangle but…
Preimplantation and prenatal genetic testing for reproductive medicine
Juno Genetics is a specialist reproductive genetics laboratory providing preimplantation genetic testing (PGT) services to IVF clinics in the UK and internationally. Using its proprietary next-generation sequencing platform, the company screens embryos for chromosomal abnormalities and single-gene disorders, and…
Automated drug discovery platform and CRO services
Arctoris is a technology-enabled contract research organisation that provides automated wet-lab biology and data generation services to biotech and pharmaceutical companies. The company operates a fully robotic, cloud-controlled platform covering biochemical, biophysical, cell-based and structural biology assays…
Real-world clinical data platform for life science research
Arcturis is a real-world data and evidence company that aggregates longitudinal, secondary-care patient records from a network of NHS hospitals into research-ready, regulatory-grade datasets. The platform combines structured and unstructured clinical data with molecular and genomic information, and is supported by HRA…
AI-driven isoform sequencing platform for movement disorder and ageing research
Entelo Bio is an Oxford-based biotechnology company developing a proprietary single-cell isoform sequencing and AI platform to decode disease biology in conditions affecting human movement and ageing. Built on research from the University of Oxford's Botnar Institute for Musculoskeletal Sciences, the platform combines…
Custom synthetic chemistry and route development for drug discovery
Cortex Organics is a contract research organisation providing custom organic synthesis, medicinal chemistry support and synthetic route development for pharmaceutical and life science researchers. Its chemists design, prepare and optimise complex small molecules, including medicinally relevant building blocks and…
Single-molecule fluorescence platform for rapid point-of-care pathogen detection
Pictura Bio is a medical technology company developing a rapid diagnostic platform that combines single-molecule fluorescent microscopy with deep learning to identify pathogens in clinical samples in under one minute. The platform uses a universal fluorescent label and a trained AI model to detect any known pathogen…
Real-time DNA and RNA sequencing at any scale
Oxford Nanopore Technologies is a biotechnology company developing and commercialising electronic nanopore sequencing instruments and consumables for the direct analysis of DNA and RNA. Its devices range from pocket-sized portable units to high-throughput benchtop systems, enabling long-read sequencing without…
Precision fermentation platform producing sustainable palm oil alternatives
Sun Bear Biofuture is an industrial biotech company developing a precision fermentation platform to produce sustainable alternatives to palm oil. Using engineered yeast strains and agricultural side streams as feedstock, the company produces oils with functional properties comparable to palm oil, targeting food…
Sustainable biopesticides and plastic-free microencapsulation for crop and animal health
Eden Research is an AIM-listed developer and supplier of sustainable biopesticides and natural microencapsulation technology for the crop protection, animal health and consumer products industries. The company's encapsulation system, derived from yeast, delivers terpene-based active ingredients as a plastic-free…
Ultrasound-based platform to enhance drug delivery into solid tumours
OxSonics is a clinical-stage biotechnology company developing a proprietary drug delivery platform that uses focused ultrasound and injectable cavitation particles to enhance the penetration of anti-cancer agents into solid tumours. The system requires no drug reformulation and includes real-time acoustic mapping to…