UK Life Sciences Company Directory

Rapid diagnostic platforms for infectious disease and consumer testing

Sapphiros is a privately held diagnostics portfolio company backed by KKR and Neoenta. UK operations include Biocrucible, a molecular diagnostics company developing ultra-rapid isothermal nucleic acid amplification assays, and an Extreme Volume Manufacturing capability producing lateral flow diagnostic tests at…

Electrochemical water contaminant sensors and mapping software

AquAffirm is a UK environmental sensing company developing portable digital tests for water contaminants and associated analytical software. Its smartphone-connected electrochemical sensors target substances including arsenic, salinity, chlorine, antibiotics and perfluorinated chemicals. The AquaFORM platform supports…

GC–MS instrumentation and software for analytical research

SepSolve is an analytical instrumentation and software company supplying gas chromatography and mass spectrometry platforms for research laboratories. Its technologies include two-dimensional GC separation, time-of-flight mass spectrometry, automated sample introduction and software for resolving complex chemical…

Needle-free solid dose vaccine formulation and delivery platform

aVaxMed Limited is a UK biotech developing the aVaxziPen platform, a proprietary needle-free, thermally stable, solid dose vaccine delivery system. The technology encapsulates vaccine antigens into unit solid doses administered via a pen applicator, removing the need for needles and reducing cold chain requirements.…

Gene therapy company targeting complement-mediated ocular diseases

Complement Therapeutics is a clinical-stage biotechnology company developing gene therapies and protein-based therapeutics for diseases driven by dysregulation of the complement immune pathway. A spin-out from the University of Manchester, the company's lead programme CTx001 is an AAV-based gene therapy for geographic…

AI-driven neuroimaging analytics for clinical trials

Queen Square Analytics is a UCL spin-out providing advanced neuroimaging data analytics for neurological clinical trials. The company applies machine learning to MRI data for patient stratification, treatment response prediction, and imaging protocol design, with a primary focus on multiple sclerosis and…

Enzymatic wound debridement therapy derived from maggot biology

SolasCure is a biotechnology company developing a recombinant enzyme-based hydrogel for the treatment of chronic wounds. The lead product contains a protease cloned from medical maggots that degrades non-viable wound tissue including fibrin, elastin, and collagen to prepare the wound bed for healing. The product is in…

Metal-based antimicrobial drugs and antibiofilm coating compounds

MetalloBio is a University of Sheffield spin-out developing metal-based antimicrobial compounds against drug-resistant bacterial infections. Its KLS-1 series includes investigational antibacterial candidate KLS-116, designed to act against multidrug-resistant pathogens and biofilms. The KLS-2 series is being developed…

Global specialist pharmaceutical company focused on HIV

ViiV Healthcare is a specialist pharmaceutical company dedicated to the research, development, and commercialisation of medicines for HIV treatment and prevention. Its portfolio includes widely used antiretroviral therapies such as Dovato and the long-acting injectable Cabenuva, and it is advancing next-generation…

Programmable RNA delivery platform targeting non-hepatic tissues

Sixfold Bioscience is a biotechnology company developing a programmable RNA-based delivery platform that exploits the body's natural extracellular RNA transport pathways to direct therapeutic RNA molecules to specific non-hepatic tissues and cell types. The platform uses computationally designed chemical modifications…

Specialist CRO for drug and agrochemical metabolite synthesis and characterisation

Hypha Discovery is a specialist contract research organisation supporting pharmaceutical and agrochemical companies worldwide. The company produces and purifies drug and agrochemical metabolites using microbial biotransformation, recombinant enzyme systems and late-stage chemical synthesis, supporting metabolite…

Novel peptide-based therapeutics and biomarkers for neurodegeneration

Neuro-Bio is a preclinical-stage biotechnology company developing a first-in-class therapeutic approach to Alzheimer's disease and related neurodegenerative disorders. Its research centres on T14, a 14 amino acid bioactive peptide derived from acetylcholinesterase, which the company has identified as a potential…

Integrated sample collection and rapid molecular diagnostic devices

ReadyGo Diagnostics develops disposable sample-collection and preparation devices for rapid diagnostic testing. Its technology combines swab collection and lysis chemistry in a single unit and is designed to work with lateral flow, molecular and immunoassay formats. It also supports rapid isothermal molecular tests…

Cancer biotherapeutics targeting disease-specific protein isoforms

Isoform Oncology is an early-stage biotechnology company developing cancer therapeutics based on isoform switching and alternative RNA splicing. The company identifies cancer-specific protein variants arising from aberrant splicing and develops biotherapeutics designed to selectively target these disease-specific…

Precision therapeutics targeting fibrosis using multi-omics

Forth Therapeutics develops precision medicines intended to target the cellular mechanisms driving organ fibrosis. Its discovery platform combines single-cell and spatial genomics with patient-derived tissue data, including a large human liver disease dataset. These insights help identify disease-associated cells and…

Rapid microfluidic antimicrobial susceptibility testing for clinical laboratories

iFAST Diagnostics is a biotechnology company developing microfluidic instruments for rapid antimicrobial susceptibility testing of bacterial infections. Its platform uses electrical measurements of individual bacteria following antibiotic exposure to determine susceptibility and minimum inhibitory concentrations in…

Semiconductor biosensors for blood-based cancer biomarker detection

ExoNostic is a diagnostic technology company developing semiconductor biosensors for cancer biomarker detection. Its investigational lab-on-a-chip platform is designed to identify molecular signatures in small blood samples, combining sensor-based measurements with computational interpretation. An Innovate UK-funded…

Health innovation district combining clinical research and biotechnology

Edinburgh BioQuarter is a health and life sciences innovation district in southeast Edinburgh, bringing together academic research, clinical healthcare and biotechnology businesses. The site hosts the Royal Infirmary of Edinburgh, University of Edinburgh medical research institutes, specialist facilities and…

Engineered bacterial protein polymers for cell culture and cultivated meat

MarraBio is a biotechnology company developing engineered Caf1-based protein polymers as xeno-free, thermostable alternatives to extracellular matrix proteins and growth factors used in mammalian cell culture. Its proprietary platform enables scalable, cost-effective production of multifunctional materials that…

AI-driven enzyme engineering platform for pharmaceutical manufacturing

Imperagen is a biotechnology company developing an automated enzyme engineering platform that combines AI-powered protein design with synthetic biology and laboratory automation. The company engineers optimised biocatalysts for pharmaceutical manufacturing, enabling greener and more efficient production of complex…