UK Life Sciences Company Directory

Small-molecule drugs targeting cellular ageing and senescence

Five Alarm Bio Limited is a biotechnology company discovering small-molecule therapies for diseases associated with ageing. Its research targets chemical damage that accumulates inside cells, aiming to reinforce protective mechanisms and delay cellular senescence rather than destroy senescent cells. Candidate…

RNA therapeutics platform targeting multiple disease pathways

SymphoRNA is a company developing RNA medicines designed to address complex diseases by targeting multiple biological pathways simultaneously. Its platform uses a polysaccharide-based delivery system to enable combination RNA therapies, with the aim of achieving outcomes that single-target approaches cannot. Spun out…

Antibody therapies depleting pathogenic T cells for autoimmune disease cure

Re-Aim Therapeutics is a biotechnology company developing antibody-based therapies designed to achieve functional cures for T cell-mediated autoimmune diseases. The company's approach selectively depletes pathogenic T cell subsets that drive chronic inflammation, using precise targeting of disease-relevant membrane…

UK manufacturer of autoclaves, sterilisers, and thermal processing equipment

LTE Scientific is a UK manufacturer and service provider of laboratory and medical equipment, specialising in autoclaves and steam sterilisers, thermal processing equipment, and controlled-environment chambers and rooms. Products serve pharmaceutical, biotech, healthcare, and research sectors, with applications…

Biologic therapies for autoinflammatory and autoimmune diseases

Kiniksa Pharmaceuticals International is a commercial-stage biopharmaceutical company focused on acquiring, developing and commercialising medicines for autoinflammatory and autoimmune diseases with significant unmet need. Its approved product, rilonacept, is an IL-1 inhibitor indicated for recurrent pericarditis. The…

Next-generation lipid nanoparticle platform for RNA vaccines and medicines

NeoVac is a biotechnology company developing a next-generation lipid nanoparticle platform to improve the delivery of RNA vaccines and therapeutics. Its library of fully biodegradable, tissue-targeted LNPs addresses limitations of first-generation formulations, offering enhanced thermostability, multiple routes of…

Specialist biomarker and bioanalytical CRO for clinical drug development

Synexa Life Sciences is a specialist contract research organisation providing biomarker and bioanalytical laboratory services to global biopharmaceutical companies. The company develops, validates, and delivers custom assays supporting clinical trials and translational studies, with expertise spanning LC-MS/MS…

No-code digital experiment platform for life science R&D

Synthace provides cloud-based software that enables life science researchers to design, automate and analyse experiments without writing code. Its platform integrates with laboratory automation hardware, structures experimental data and applies design of experiments methodologies, with a primary focus on assay…

Tunable covalent chemistry platform for neurodegenerative disease

Dunad Therapeutics is a drug discovery biotech developing small molecule therapies for neurodegenerative diseases including ALS, frontotemporal dementia, and Parkinson's disease. Its platform combines tunable covalent chemistry with targeted protein degradation, using monovalent small molecules that form durable bonds…

Multiplex PCR pathogen detection kits for infectious disease diagnostics

Genetic Signatures is a molecular diagnostics company supplying multiplex real-time PCR detection kits for infectious disease testing in hospital and pathology laboratories. Its proprietary technology simplifies genetic sequences to improve multiplex efficiency and increase resistance to pathogen mutation,…

T cell immunotherapies for infectious disease, cancer and autoimmunity

Barinthus Biotherapeutics is a clinical-stage biopharmaceutical company developing antigen-specific T cell immunotherapies for chronic infectious diseases, autoimmune conditions, and cancer. Its pipeline is built on four proprietary viral vector and synthetic immunotherapy platforms and includes clinical candidates…

Seaweed-derived biodegradable materials for sustainable packaging

Notpla is an industrial biotechnology company developing biodegradable packaging materials from seaweed and other plant-derived polymers. Its technology uses natural biopolymers to create edible liquid capsules, flexible films, protective coatings and moulded materials designed to replace conventional plastic…

Bacteriophage platform for targeted bacterial crop disease management

Greenleaf Bio is a biotech developing engineered bacteriophage-based crop protectants against bacterial plant pathogens. The platform combines synthetic biology, phage engineering, and machine learning to accelerate the discovery and development of species-specific, non-toxic biopesticides that offer an…

Coronary plaque biomarkers for precision cardiovascular medicine

PlaqueTec develops a catheter-based liquid biopsy system to investigate biological processes driving coronary artery disease. Its device samples blood at sites around coronary plaques, allowing researchers to compare local concentrations of proteins and other molecules. These data feed its BioCarta platform for…

Clinical-stage biopharma improving nucleoside analogue chemotherapy efficacy

NuCana is a clinical-stage biopharmaceutical company developing a pipeline of cancer medicines using proprietary phosphoramidate prodrug chemistry. Its approach transforms established nucleoside analogue chemotherapy agents into modified forms that bypass key tumour resistance mechanisms, delivering higher…

Novel ADC payloads targeting NMT enzymes in cancer

Myricx Bio is a clinical-stage biotechnology company developing a novel class of antibody-drug conjugate payloads based on inhibition of N-myristoyltransferase, an enzyme essential to cancer cell survival. Its NMTi payload chemistry platform addresses limitations of existing ADC payloads, including resistance and…

Plant-based expression platform for recombinant protein production

Bright Biotech is a UK CDMO developing and applying a proprietary plant-based expression system for the production of recombinant proteins. Its platform uses chloroplast engineering in tobacco plants to express high yields of target proteins, offering an animal-free and scalable alternative to conventional cell-based…

Biological sensors that detect early crop stress signals

Viridys Bio is a synthetic biology company developing non-GMO biosensors that detect volatile organic compounds released by stressed plants. The sensors give a visual colour change alert before pest or disease symptoms become visible, allowing growers to intervene earlier and more precisely. Designed to require no…

Hollow fibre bioreactor technology for cultivated food and cell culture

Cellular Agriculture is a UK biotech developing modular hollow fibre bioreactor systems to enable scalable cell culture for cultivated food production and broader biomanufacturing applications. The company supplies bioreactor technology to food producers and biopharma partners rather than producing cultivated products…

London life sciences cluster organisation and inward investment body

MedCity is the cluster organisation for the life sciences sector in London, operating as a division of London & Partners, the Mayor of London's growth agency. Founded in 2014 in partnership with London's Academic Health Science Centres, MedCity promotes London as a global destination for life sciences investment,…