Company Directory

Carbohydrate binding molecules targeting the tumour glycome in cancer

Omideon is a Scottish preclinical biotechnology company applying multivalent carbohydrate binding molecule (mCBM) technology to oncology. Spun out from Pneumagen Limited by demerger in 2020, the company uses genetic engineering to develop mCBMs with high affinity for tumour-associated terminal glycans. Its lead candidate, OMI-DG1, is a first-in-class mCBM in development for ovarian cancer and colorectal cancer, with preclinical in vivo proof of concept demonstrated for ovarian cancer.

Glycan analysis products and services for biopharmaceutical QC

Ludger is a glycobiology company specialising in the measurement and characterisation of protein glycosylation for biopharmaceutical development and quality control. The company manufactures glycan analysis kits, reagents, and reference standards for use in LC, MS, and CE workflows, and provides contract analytical services and regulatory consulting to support IND submissions and comparability studies. Ludger's products are used in the quality control of FDA- and EMA-approved biopharmaceuticals and biosimilars worldwide.

Synthetic glucose-binding molecules for continuous glucose monitoring

Carbometrics Limited is a supramolecular chemistry biotech developing synthetic Glucose Binding Molecules (GBMs) for use in continuous glucose monitoring sensors and other diagnostic applications. The GBM platform uses a precisely engineered small-molecule scaffold to selectively bind glucose with high affinity and specificity, enabling interference-free sensing across a range of transduction modalities including optical and electrochemical signal detection. The technology originates from two decades of research at the University of Bristol.

Synthetic chemical receptor R&D for implantable glucose biosensors

Lifecare Chemistry Ltd is a UK R&D subsidiary of Norwegian medical sensor company Lifecare ASA, established to develop and own proprietary analyte-specific synthetic receptors for use in Lifecare's implantable continuous glucose monitoring technology. Working in collaboration with researchers at the University of Bath, the company applies boronic acid-based supramolecular chemistry to engineer glucose-selective receptor molecules that drive osmotic pressure changes within a miniaturised sensor, with scope to extend detection to additional metabolic analytes.

Cyanobacterial synthetic biology platform producing sustainable specialty chemicals

Deep Blue Biotech is a biotechnology company using genetically engineered cyanobacteria to produce high-value specialty chemicals as sustainable alternatives to fossil-derived ingredients. The platform uses carbon dioxide, light, and water as primary inputs, guided by AI-driven metabolic modelling, to manufacture carbohydrate-based compounds including hyaluronic acid. Target markets include cosmetics, personal care, and pharmaceutical manufacturing.

Broad-spectrum intranasal antivirals targeting respiratory viral infections

Pneumagen is a Scottish clinical-stage biotechnology company developing broad-spectrum intranasal antiviral therapies. Pneumagen’s platform generates multivalent carbohydrate binding molecules (mCBMs) that block viral entry by binding to sialic acid residues on host epithelial cells. Its lead candidate Neumifil has demonstrated positive results in Phase II human challenge studies for influenza and is being advanced into Phase II studies in COPD patients. Pneumagen also develops a mucosal retention platform for intranasal biologics.

Glycan-based biological age and inflammaging diagnostics

GlycanAge is a biotechnology company that develops and sells diagnostic tests based on IgG glycan biomarkers. Its flagship product analyses glycans from a finger-prick blood sample to determine a customer's biological age, reflecting the degree of chronic inflammation driving immune ageing. Tests are available direct-to-consumer and through healthcare providers. The company is expanding into clinical diagnostics, including hospital-based lab-developed tests and indication-specific products for cardiometabolic health and hormonal health.