Biotechnology companies apply biological science to develop products, services and technologies that address challenges in healthcare, agriculture, industry and environmental sustainability.
This category includes companies working on:
Browse 360 UK biotechnology companies below.
AI and photonics platform for personalised drug development
iLoF is a digital health company developing an AI-powered platform that uses proprietary photonics technology to generate optical fingerprints from blood samples, building a cloud-based library of biological profiles and biomarkers. The platform enables non-invasive patient stratification and personalised drug…
Targeted magnetic blood filtration to enable gene therapies
MediSieve is a biotechnology company developing selective magnetic blood filtration using engineered particles that bind specific circulating biological targets. Its extracorporeal system combines target-specific magnetic beads with a capture device designed to remove bound substances before blood returns to the…
Breath-based molecular liquid biopsies for early lung cancer detection
Respiro Diagnostics is a biotechnology company developing non-invasive molecular diagnostics for respiratory diseases, initially focusing on lung cancer. Its investigational platform collects exhaled breath samples and analyses lung-derived molecular biomarkers, including nucleic acids and proteins, to support earlier…
Cell-specific mRNA delivery platform for genetic medicines
Nuntius Therapeutics is a London-based biotechnology company developing mRNA therapies using proprietary peptide dendrimer and lipid-based nanocarriers designed to deliver genetic payloads to tissues and cell types beyond the liver. The platform combines machine learning-guided carrier design with engineered mRNA…
AI genomics for drug target discovery
OutSee is a genomics and drug discovery company using proprietary AI technology to identify and validate novel therapeutic targets. Its core platform applies predictive algorithms to large-scale genomic datasets to uncover disease-modulating biological mechanisms, complementing traditional analysis methods. OutSee…
AI vision systems for surgical workflows and cell therapy manufacturing
Appraiseye develops AI-powered vision systems for life sciences and healthcare applications across two platforms. Its operating theatre intelligence platform provides real-time instrument tracking, tray utilisation analytics and sterile processing optimisation for surgical departments. Its platform applies AI-guided…
Computational DNA design for durable genetic medicines
Houdini Bio is an early-stage biotechnology company using computational synthetic biology to redesign DNA for improved performance in genetic medicines. The company is developing approaches to enhance the durability and scalability of gene expression, with potential applications across gene therapies and DNA-based…
ENTECH platform for cell perturbation and AI target discovery
Aparna Bio develops technologies for generating biologically relevant cell-perturbation data to support drug target discovery. Its ENTECH platform is being engineered to deliver experimental perturbation reagents into primary human cells and other disease-relevant models, where conventional delivery methods can be…
Perfluorocarbon oxygen carrier therapeutic and MRI imaging agent for acute stroke
Aurum Biosciences is a Scottish clinical-stage biopharmaceutical company developing ABL-101, a perfluorocarbon-based oxygen carrier that bypasses arterial clots to deliver oxygen to ischaemic tissue via collateral vessels. The lead indication is acute ischaemic stroke, with ABL-101 having completed Phase 1 and 2a…
Modular automated RNA manufacturing platform
Centillion is a UK biotech company whose platform integrates synthesis, purification, and formulation stages using continuous flow chemistry to produce mRNA and self-amplifying RNA at research and production scale. The platform supports process development through to regulatory-ready CMC packages and is available as a…
Infrared spectroscopy blood test for early multi-cancer detection
Dxcover is a clinical-stage biotechnology company developing a blood-based multi-cancer early detection test. Its platform applies infrared spectroscopy to a dried blood spot to capture a pan-omic biological signature spanning proteins, lipids, metabolites, and nucleic acids simultaneously. Machine learning algorithms…
Next-generation lipid nanoparticle platform for RNA vaccines and medicines
NeoVac is a biotechnology company developing a next-generation lipid nanoparticle platform to improve the delivery of RNA vaccines and therapeutics. Its library of fully biodegradable, tissue-targeted LNPs addresses limitations of first-generation formulations, offering enhanced thermostability, multiple routes of…
GPR35 inhibitors for gastrointestinal cancer and inflammatory bowel disease
ThirtyFiveBio is a drug discovery company developing first-in-class small molecule inhibitors of GPR35, a genetically validated G protein-coupled receptor implicated in gastrointestinal disease. The company's approach targets GPR35 antagonism to prevent epithelial cell damage and dysfunction in the gut wall,…
Tissue-based endometriosis models for therapeutic target discovery
Cyclana Bio is a biotechnology company developing human tissue-based models to investigate endometriosis and identify therapeutic targets. Its research combines endometrial tissue biopsies and menstrual fluid samples with molecular profiling and three-dimensional disease models, focusing on extracellular matrix…
RNA sequencing liquid biopsy for cardiovascular and complex disease screening
MultiplAI Health is a Cambridge biotech developing a whole-blood RNA sequencing test for early screening of cardiovascular and other complex diseases. Its platform combines transcriptomic profiling of blood samples with a patented data transformation process and proprietary deep learning algorithms to generate…
Integrated NGS assays for genomic profiling of haematological malignancies
Univ8 Genomics is a Belfast-based genomics diagnostics company developing targeted next-generation sequencing assays for the integrated clinical characterisation of haematological malignancies. Its assays enable simultaneous detection of clonal rearrangements, chromosomal translocations, copy number alterations and…
High-throughput iPSC reprogramming and stem cell drug discovery services
Oxford StemTech is a contract research company providing induced pluripotent stem cell (iPSC) reprogramming and drug discovery services using its proprietary platform. The technology enables large-scale, cost-effective generation of patient-derived iPSC lines from blood or skin samples, supporting disease modelling,…
Therapeutics targeting lysosomal dysfunction in neurodegeneration
Endlyz Therapeutics is a preclinical-stage biotechnology company developing small molecule modulators to restore endo-lysosomal function in Parkinson's disease and related neurodegenerative conditions. Its lead programmes target ATP13A2 and ATP10B, lysosomal transporter enzymes linked to neuronal health and…
CreaTap antibody engineering for improved solid tumour penetration
Creasallis is a biotechnology company developing antibody engineering technologies intended to improve drug delivery into solid tumours. Its patented CreaTap platform modifies therapeutic antibodies to promote deeper penetration into tumour tissue. The approach is under development for monoclonal antibodies,…
AAV gene therapies for rare neurological diseases of childhood
BlackfinBio is a biotechnology company developing AAV-based gene therapies for rare neurodegenerative diseases of the central nervous system, with an initial focus on children. Its lead programme is a one-time gene therapy administered directly to the brain, designed to treat a group of ultra-rare dopamine deficiency…