Biotechnology companies apply biological science to develop products, services and technologies that address challenges in healthcare, agriculture, industry and environmental sustainability.
This category includes companies working on:
Browse 360 UK biotechnology companies below.
Rapid airborne DNA sequencing service for pathogen detection and biosecurity
Agnos Biosciences is a deep tech company commercialising AirSeq, a rapid DNA air sequencing technology for the detection and quantification of airborne biological material. AirSeq combines novel molecular biology, DNA sequencing and bespoke computational analysis to simultaneously identify thousands of species,…
Multiomics blood-based platform for early-stage cancer detection
Freenome is a biotechnology company developing blood-based early cancer detection tests using a multiomics platform that combines tumour and non-tumour biological signals with machine learning. The UK subsidiary, based in Nottingham, holds the autoantibody immunodiagnostic technology and cancer detection pipeline…
Anti-virulence drug discovery from natural bioactive compounds
Neem Biotech is a Wales-based drug discovery company developing novel non-traditional antimicrobial treatments derived from naturally inspired compounds. The company specialises in quorum sensing inhibitors and anti-biofilm agents, with programmes targeting wound infection and cystic fibrosis. Its discovery approach…
Rapid point-of-care molecular diagnostics for infectious disease
Llusern Scientific is a diagnostics company developing portable, rapid molecular diagnostic systems for use at the point of care. Using isothermal amplification technology, the company's platform identifies bacterial pathogens directly from patient samples without laboratory infrastructure, delivering results within…
Oral small-molecule therapies targeting autoimmune disease pathways
SMIN Therapeutics is a biotechnology company developing oral medicines for autoimmune diseases. Its drug discovery platform studies interactions between proteins to identify therapeutic compounds, with an initial focus on the neonatal Fc receptor (FcRn), which regulates immunoglobulin G (IgG). The company is…
Macrophage-based reprogramming of the innate immune system
Ojas Immune develops therapies that reprogramme macrophages, innate immune cells involved in inflammation, tissue repair and disease. Its platforms combine synthetic biology, stem cell engineering and computational modelling. SyntheMacs focuses on engineered macrophage cell therapies, while ReProMacs explores…
Clinical-stage anti-infectives targeting antimicrobial resistance and infectious disease
NovaBiotics is a clinical-stage biotechnology company developing first-in-class anti-infective therapies for difficult-to-treat infectious diseases, with a focus on antimicrobial resistance. Its pipeline is built on two proprietary platforms: an anti-infective peptide platform yielding antifungal and antibacterial…
AI-designed regulatory DNA sequences to boost biologics manufacturing yields
Genosys Bio is a UK biotechnology company developing AI models that learn the regulatory grammar of DNA to design improved promoter and terminator sequences for biologics manufacturing. Its platform optimises gene expression in CHO cell lines, helping increase protein yields without changing existing cells, processes…
Multiplex PCR and NGS diagnostics for cancer and infection
GeneFirst is a molecular diagnostics company developing multiplex PCR assays and next-generation sequencing technologies for cancer screening, precision oncology and infectious disease testing. Its Papilloplex assays detect high-risk human papillomavirus DNA or E6/E7 mRNA. The XCeloSeq platform provides library…
Sustainable conjugation technology for antibody-drug conjugate manufacturing
Vitamab is a Manchester-based biotechnology company developing conjugation technology to strengthen the antibody-drug conjugate manufacturing supply chain. Its proprietary system uses accessible, lower-toxicity materials in place of scarce or hazardous reagents, aiming to reduce production costs and environmental…
Point-of-care HPV self-testing for cervical cancer screening
10zyme is an early-stage medical technology company developing a point-of-care self-test for high-risk human papillomavirus, integrating synthetic biology with machine learning to deliver instant results without laboratory processing. Its test screens for all 14 high-risk HPV types linked to cervical cancer,…
Sustained-release ocular drug delivery for retinal disease
Re-Vana Therapeutics is a biotechnology company developing sustained-release drug delivery technologies for the treatment of serious retinal diseases. Its biodegradable hydrogel platform uses photo-crosslinking to form in-situ implants administered via intravitreal injection, enabling controlled release of biologics,…
Enzyme-free multiplex RNA diagnostics for rapid clinical decisions
Cambridge Nucleomics is a biotechnology company developing a proprietary nanopore-based platform for rapid, high-multiplexed detection of nucleic acid biomarkers. Its enzyme-free soluble nanoarray technology enables simultaneous quantification of up to 200 RNA and DNA targets from low-input samples within one hour.…
Polymer-based rapid diagnostic technology for bacterial and fungal infections
Molecular Titans is a University of Bradford spin-out developing a patented polymer nanotechnology platform for rapid infection diagnosis. Its thermoresponsive polymers bind selectively to bacterial and fungal pathogens, producing a measurable signal within minutes rather than days. Initial applications include…
Predictive genetic tests for cancer and cardiovascular disease
GENinCode is a clinical-stage diagnostics company developing polygenic risk assessment tests for cardiovascular disease and ovarian cancer. Its portfolio includes CE-marked molecular tests for coronary artery disease, familial hypercholesterolaemia and thrombosis risk, alongside the ROCA test for ovarian cancer…
Oncology biotech creation studio developing and spinning out cancer therapies
Cumulus Oncology is a company creation studio specialising in oncology drug discovery and development. The company identifies and sources novel cancer therapeutic assets from academic and commercial organisations, funds them, and incorporates them into newly created spin-out biotechs. Cumulus provides scientific…
Therapeutics and blood biomarker tests for ALS
Vesalic develops therapeutic and diagnostic approaches for amyotrophic lateral sclerosis (ALS), focusing on the potential role of metabolic dysfunction outside the nervous system. Its preclinical programmes include a treatment candidate designed to address toxic cargo carried by exosomes to motor neurons, alongside a…
Rapid microfluidic antimicrobial susceptibility testing for clinical laboratories
iFAST Diagnostics is a biotechnology company developing microfluidic instruments for rapid antimicrobial susceptibility testing of bacterial infections. Its platform uses electrical measurements of individual bacteria following antibiotic exposure to determine susceptibility and minimum inhibitory concentrations in…
Next-generation ADC linker chemistry for precision cancer therapeutics
Siftr Bio is a biotechnology company developing novel linker chemistry for antibody-drug conjugates. Current ADC linkers have limited diversity and insufficient selectivity, contributing to off-target toxicity that restricts their therapeutic application. Siftr's platform screens enzyme-responsive linker candidates…
Microbiome-targeted probiotic and prebiotic supplements for clinical practice
Invivo Healthcare is a supplement company developing probiotic, prebiotic and botanical formulations designed to support the human microbiome. Its ranges target gut, immune and vaginal microbiome health, and are manufactured to GMP standards. The company supplies healthcare practitioners and their patients, and also…