Biotechnology companies apply biological science to develop products, services and technologies that address challenges in healthcare, agriculture, industry and environmental sustainability.
This category includes companies working on:
Browse 360 UK biotechnology companies below.
Cell therapy for vascular regeneration in ischaemic and wound healing conditions
VascVersa is a Belfast-based regenerative medicine company developing cell therapies for vascular regeneration and repair. The company's technology uses vasoreparative cells to stimulate new blood vessel formation and restore blood supply in conditions characterised by impaired circulation. The lead programme targets…
Carbon nanodot delivery platform for RNA-based crop protection
CDotBio Limited is a biotech developing carbon nanodot technology to improve the delivery and stability of RNA-based biopesticides and other crop inputs. The platform uses ultra-small, sugar-derived nanoparticles to protect RNA cargo from degradation as it transits into plant cells, enabling species-specific targeting…
NGS liquid biopsy testing for cancer in dogs and cats
CanCan Diagnostics is a veterinary biotechnology company developing next-generation sequencing tests for cancer detection and monitoring in companion animals. Its K9 LiquiDx liquid biopsy analyses tumour-associated mutations in circulating cell-free DNA from canine blood samples. The company also offers tissue-based…
Therapeutic antibodies targeting the angiotensin AT1R pathway in cancer
aTen Therapeutics is a Scottish pre-clinical biotechnology company developing therapeutic monoclonal antibodies against the angiotensin-II type I receptor (AT1R), which is overexpressed across a range of cancers. Its lead candidate, Tensinumab (ATN-E11), is a human monoclonal antibody generated via phage display that…
Non-invasive small molecule eye drops for retinal vascular disease
Foventa is a biopharmaceutical company developing non-invasive, small molecule therapeutics for retinal vascular diseases that can cause vision loss. Its lead candidate targets VEGF splicing, a mechanism underlying abnormal blood vessel growth in conditions including diabetic retinopathy and diabetic macular oedema.…
Synthetic mycolic acid antigens and point-of-care TB diagnostics
Diagnostig is a Welsh diagnostics and chemical synthesis company developing point-of-care immunoassay devices for the diagnosis of mycobacterial infections, including human and bovine tuberculosis. The company's technology is based on fully synthetic mycolic acids, chemically defined cell wall components unique to…
Synthetic gene promoter platform for biologics and cell and gene therapy
SynGenSys is a synthetic biology company developing proprietary libraries of synthetic gene promoters and signal peptides designed to improve the yield, specificity, and reliability of recombinant protein expression. Its computational platform uses bioinformatics and AI to design novel promoters from first principles,…
Rapid point-of-care antibiotic susceptibility testing for antimicrobial resistance
Microplate Dx is a diagnostics biotechnology company developing a rapid antibiotic susceptibility testing platform for use at the point of care. Its biosensor technology uses hydrogel-modified electrodes loaded with antibiotics to determine the most effective treatment for a patient's bacterial infection in under one…
Jellyfish-derived collagen biomaterials for research and regenerative medicine
Jellagen is a Welsh biotechnology company developing and manufacturing collagen biomaterials derived from sustainably harvested jellyfish. Its proprietary Collagen Type 0 is compatible with a broad range of human cell types, making it suitable for cell culture, tissue engineering, wound care, and regenerative medicine…
Ultra-high-throughput biologics discovery platform powered by generative AI
Sortera Bio is a biotechnology company developing an AI-powered platform for the discovery and engineering of biological therapeutics. The Deep Screening platform generates sequence and functional data across hundreds of millions of biologics in a single experiment, producing large-scale training datasets for…
Natural antimicrobial solutions to reduce livestock antibiotic use
Feed, Food & Future is a life sciences company developing and testing natural antibacterial and antiviral ingredients for the animal feed and livestock industries. Operating from a BSL2 laboratory at Cardiff Medicentre, the company researches plant-based and natural molecules as alternatives to conventional…
Immunotherapies targeting blood cancer precursor conditions before onset
Athernal Bio is a Cambridge-based biotechnology company developing targeted immunotherapies for high-risk clonal haematopoiesis, a widespread blood stem cell mutation condition that significantly increases the risk of acute myeloid leukaemia and other haematological cancers. The company's pipeline comprises three…
Ultrasound-based platform to enhance drug delivery into solid tumours
OxSonics is a clinical-stage biotechnology company developing a proprietary drug delivery platform that uses focused ultrasound and injectable cavitation particles to enhance the penetration of anti-cancer agents into solid tumours. The system requires no drug reformulation and includes real-time acoustic mapping to…
AI and multi-omics platform for cardiovascular drug target discovery
CardiaTec Biosciences is a Cambridge-based biotech applying artificial intelligence to large-scale multi-omic data to identify novel drug targets for cardiovascular diseases. Its platform integrates data across genomic, epigenomic, transcriptomic, proteomic and metabolomic layers to map disease mechanisms and uncover…
Preclinical vaccines targeting antimicrobial-resistant bacterial infections
VacTimmune is a biotechnology company developing preventative vaccines against bacterial pathogens associated with antimicrobial resistance. Its preclinical pipeline includes candidates targeting Pseudomonas aeruginosa, Klebsiella pneumoniae and other clinically important bacteria, with an emphasis on infections…
Mitochondrial transplantation platform to restore cellular energy and regeneration
Recondria Therapeutics is a developer of a mitochondrial transplantation platform designed to restore cellular energy, accelerate tissue recovery and support regenerative medicine. The company's approach involves isolating healthy mitochondria and delivering them to damaged cells to restore ATP production and cellular…
Host-response biomarker test to rapidly diagnose sepsis
Profionics is a diagnostics company developing a precision molecular test for rapid sepsis detection. Its platform analyses 52 patient-invariant biomarkers spanning inflammatory, metabolic, and adaptive immune pathways, using transcriptomics, metabolomics, and lipidomics in combination with artificial intelligence.…
T-cell immune profiling diagnostics and immunology research reagents
Virax Biolabs develops diagnostic tests that measure T-cell immune responses to viral infections. Its lead assay focuses on post-acute infection syndromes, including long COVID, and is intended to help characterise patients' cellular immune responses. The company also supplies immunology research reagents, including…
Somatic genomics for genetically validated drug target discovery
Quotient Therapeutics is a biotechnology company developing medicines from genetic differences between cells within the same person. Its somatic genomics platform combines sensitive DNA sequencing, cell analysis and computational biology to identify mutations linked to disease resistance or susceptibility. These…
AI-powered cell simulation platform targeting ageing and age-driven diseases
Shift Bioscience is a biotechnology company developing an AI-powered virtual cell platform to identify novel therapeutic targets for cellular rejuvenation. Its proprietary single-cell ageing clock measures epigenetic age at high throughput, feeding machine learning models that predict gene combinations and small…