Biotechnology companies apply biological science to develop products, services and technologies that address challenges in healthcare, agriculture, industry and environmental sustainability.
This category includes companies working on:
Browse 360 UK biotechnology companies below.
Phenotypic screening platform for targeted protein degradation drug discovery
PhoreMost is a drug discovery company developing a phenotypic screening platform to identify and prosecute previously undruggable disease targets. The platform systematically unmasks cryptic binding sites across the human proteome and links them to therapeutic functions in a live-cell context, enabling the discovery…
Multiplexed imaging platform for therapeutic mechanism of action discovery
Micrographia Bio is a biotechnology company developing a spatial proteomics platform for drug discovery. Its technology combines highly multiplexed microscopy with machine-intelligent computer vision to autonomously determine the mechanism of action of therapeutic candidates by visualising protein-protein interactions…
Mitochondrial DNA liquid biopsy tests for cancer and disease detection
MDNA Life Sciences is a biotechnology company developing proprietary diagnostic tests based on mitochondrial DNA biomarkers. Its technology detects specific mitochondrial DNA deletions in blood and tissue samples as indicators of disease, enabling non-invasive testing for conditions that are difficult to diagnose.…
AI-driven discovery of fungal natural product therapeutics
Novogaia is a biotechnology company using machine learning and analytical chemistry to discover drug-like molecules from fungi. Its Gaia-01 model predicts molecular structures from mass spectrometry data, enabling researchers to characterise natural compounds and identify chemical starting points for drug discovery.…
High-capacity viral vector manufacturing platform for gene therapy
Icosphere Biosciences is a biotechnology company developing manufacturing technology for high-capacity gene therapy vectors. Its platform enables scalable, high-yield, contamination-free production of high capacity adenoviral vectors capable of carrying substantially more genetic material than conventional viral…
Raman spectroscopy blood test for early cancer detection
CanSense is a Welsh biotechnology company developing a non-invasive blood test for the early detection of bowel and other cancers. The platform combines Raman laser spectroscopy with artificial intelligence to identify cancer-associated metabolic signatures in blood, delivering results within 48 hours without…
End-to-end production systems for cultivated meat
Cellcraft is a biotechnology company developing integrated systems for cultivated meat production. The company supplies the hardware, software, and biological inputs required to grow animal cells outside the body at commercial scale, targeting food producers and manufacturers seeking slaughter-free protein production.…
Causal cellular data and AI models for drug discovery
CellCodex is a biotechnology company that generates causal data from human cells to train predictive models for drug discovery. It programmes stem cells into pure, aged, disease-relevant cell types, perturbs them at genome scale with CRISPR and compounds, and reads the outcome in single cells. The company applies the…
XF-73 antimicrobial advancing towards Phase 3 infection prevention
AMR Bio is a clinical-stage biotechnology company developing the XF-73 antimicrobial platform for preventing hospital-acquired infections. Its lead nasal formulation aims to reduce Staphylococcus aureus carriage before surgery. Following Phase 2b clinical testing, the programme is preparing for Phase 3 development.…
Targeted oncology combination therapies in biomarker-defined cancer populations
Mosaic Therapeutics is a Cambridge biotech developing targeted combination therapies for cancer. Its proprietary platform integrates genome-scale CRISPR screening, high-throughput combination drug testing across over 1,300 patient-derived tumour models, and advanced computational analysis to identify synergistic drug…
Gene therapy platform delivering precision cancer treatments
Trogenix is a clinical-stage biotechnology company developing precision gene therapies for aggressive solid tumours. Its platform uses proprietary synthetic super-enhancers, engineered genetic constructs delivered via AAV vectors, to selectively activate in cancer cells and simultaneously trigger tumour cell death and…
AI-powered gut microbiome analysis for personalised clinical nutrition
Enbiosis is a biotechnology company combining whole-genome gut microbiome sequencing with artificial intelligence to generate personalised nutrition, dietary, and supplement recommendations for patients with gastrointestinal disorders. Its B2B platform is used by healthcare professionals including gastroenterologists…
AI-designed aptamer therapeutics for undruggable targets
PentaBind is a TechBio company using generative AI to design aptamers with drug-like properties for targets that are inaccessible to conventional modalities. Its platform combines proprietary datasets with wet-laboratory validation to deliver multi-attribute aptamer candidates in a fraction of the time and cost of…
Injectable biomaterial gel to treat degenerative disc disease
Orthoson is a medtech company developing micro-invasive injectable treatments for chronic back pain caused by degenerative disc disease. Its lead product, a patented pNIPAM-DMAc co-polymer hydrogel, is designed to be injected into the intervertebral disc, where it gels in-situ to restore the mechanical and biological…
Veterinary vaccine R&D and licensing for livestock infectious diseases
Cambivac develops and licenses veterinary vaccine technologies, combining genomic research with traditional virology and molecular approaches. Its documented development programmes include vaccines for foot-and-mouth disease and porcine reproductive and respiratory syndrome, a respiratory disease affecting pigs. The…
Bioelectronic chips using living microorganisms for rapid chemical sensing
Kāhu SiliconBio is developing a bioelectronic sensor that integrates living, bioengineered microorganisms directly into silicon chips to detect trace chemicals in liquids. The company's BioChip generates an electrical signal proportional to chemical concentration, enabling rapid, on-site measurement without laboratory…
Automated benchtop instrumentation for rapid protein and viral vector quantification
Abselion develops automated analytical instrumentation for biomolecule quantification in biopharmaceutical research and manufacturing. Its technology enables rapid quantification of antibodies, AAVs and other proteins directly from crude samples without optics or fluidics. The platform is designed for at-line use in…
Gene therapies targeting the ageing process and age-related disease
Genflow Biosciences is a longevity-focused biotechnology company developing gene therapies designed to slow or halt the biological ageing process and delay age-related disease. Its lead compound uses an adeno-associated viral vector to deliver a centenarian variant of the SIRT6 gene, with a pipeline spanning human and…
Antigen modulation therapies for cancer and autoimmune disease
Grey Wolf Therapeutics is a clinical-stage biotechnology company developing small molecule inhibitors of endoplasmic reticulum aminopeptidases (ERAP1 and ERAP2) to modulate antigen presentation on cell surfaces. In oncology, this approach enhances tumour visibility to the immune system; in autoimmunity, it aims to…
Small molecule regulators of mitochondrial transfer for age related disease
Nascent Therapeutics is a biotechnology company developing small molecule therapies that regulate mitochondrial transfer between cells. The company's discovery platform identifies compounds that promote the uptake of healthy mitochondria into damaged cells, or block cancer cells from taking mitochondria from…