Biotechnology companies apply biological science to develop products, services and technologies that address challenges in healthcare, agriculture, industry and environmental sustainability.
This category includes companies working on:
Browse 360 UK biotechnology companies below.
MicroRNA therapeutics for tendon and musculoskeletal disease
Causeway Therapeutics is a clinical-stage biotechnology company developing first-in-class microRNA therapies for musculoskeletal and age-related conditions. Its lead asset TenoMiR (CWT-001) is a synthetic miR-29a mimic delivered by single intratendinous injection that promotes collagen remodelling and tendon repair.…
Microbial soil amendments for crop drought resilience
CroBio is an agricultural biotechnology company developing living microbial soil amendments to improve crop drought resilience. Its microorganisms use plant root exudates to produce bacterial cellulose, creating a water-retentive matrix around roots that can also help retain nutrients. The technology is progressing…
Organ-on-a-chip systems for human-relevant preclinical drug testing
CN Bio is a UK biotechnology company developing organ-on-a-chip microphysiological systems for preclinical drug discovery and safety testing. Its platform recreates human organ microarchitecture using primary cells and microfluidic perfusion, enabling researchers to generate human-relevant efficacy, metabolism and…
Systemic viral immunotherapy for solid tumours
Stratosvir develops engineered viral immunotherapies for advanced solid tumours and their metastases. Its platform aims to overcome the limitations of injecting therapeutic viruses directly into tumours by enabling systemic, intravenous delivery. Within tumour tissue, the viruses are designed to replicate selectively…
FDA-approved AI blood test for diabetic kidney disease risk
Renalytix is an artificial intelligence-enabled in vitro diagnostics company focused on the clinical management of chronic kidney disease. Its blood-based test combines biomarker analysis with machine learning to generate a five-year kidney function decline risk score in adults with type 2 diabetes and CKD stages 1 to…
AI-driven liquid biopsy platform for early cancer biomarker discovery
BioMavericks is an early-stage biotechnology company developing an AI-driven liquid biopsy platform for the early detection of cancer. Its lead product targets the discovery and validation of blood-based biomarkers for early-stage pancreatic cancer diagnostics, integrating molecular cell biology, multi-omics data…
Isothermal molecular diagnostics and assay development services
Simplex Molecular is a biotechnology company developing instrument-free nucleic acid testing technology alongside molecular biology research services. Its proprietary isothermal amplification chemistry operates at room temperature and is being developed into a portable, multiplexed diagnostic platform with…
Precision-programmed human iPSC-derived cells for biomedical research
bit.bio is a Cambridge-based synthetic biology company that programmes human induced pluripotent stem cells into defined, mature cell types for use in pharmaceutical and academic research. Its precision cell programming technology produces consistent, characterised human cells at industrial scale, supporting drug…
Canine gut microbiome testing and personalised supplement service
BIOME9 is a canine health company providing at-home gut microbiome testing and personalised supplement plans for dogs. Using stool sample analysis and AI-assisted interpretation, the company generates detailed gut health reports identifying microbial imbalances and tailored dietary recommendations. Operating as the…
Non-invasive mitochondrial DNA damage testing for skin health research
Skin Life Analytics is a biotechnology company providing PCR-based testing services that quantify mitochondrial DNA damage in skin using non-invasive swab sampling. The technology detects molecular markers of skin ageing, UV damage, and environmental stress before visible signs appear. Services include direct testing…
Rejuvenation biology company decoding the genomics of cellular ageing reversal
clock.health is a biotechnology company developing therapies to reverse cellular ageing and extend healthspan by decoding the biological programmes that govern cell rejuvenation. Using a proprietary model in which human induced pluripotent stem cells are artificially aged then permitted to self-rejuvenate, the company…
DNA methylation blood tests for ovarian and pancreatic cancers
GenoME Diagnostics is a biotechnology company developing molecular blood tests for cancer detection and monitoring. Its liquid biopsy platform identifies DNA methylation and fragmentomic biomarkers, combining them into multiplexed droplet digital PCR assays. Its lead test targets ovarian cancer recurrence and…
Blood glycomic biomarkers for chronic inflammatory disease detection and monitoring
Avenna is a biotechnology company developing blood-based glycomic biomarkers for chronic inflammatory diseases. Its tests analyse the sugar structures attached to blood proteins to measure chronic inflammation separately from short-term acute inflammation, supporting early detection, disease monitoring and…
Bacteriophage antimicrobials targeting livestock pathogens to replace antibiotics
Aparon is a biotechnology company developing bacteriophage-based technologies as novel antimicrobials for use in livestock production. Its research focuses on identifying and formulating bacteriophage cocktails that selectively destroy bacterial pathogens in animals, offering an alternative to conventional antibiotic…
RNAi brain shuttle platform for neurodegenerative disease drug delivery
Aerska is a biotechnology company developing RNA interference medicines to treat, delay and prevent diseases of the brain. The company's antibody oligonucleotide conjugate platform acts as a brain shuttle, enabling RNAi therapeutics to cross the blood brain barrier and reach the central nervous system through systemic…
Blood-based CIZ1B biomarker test for early-stage lung cancer detection
Cizzle Biotechnology is a UK-based diagnostics company developing a non-invasive blood test for the early detection of lung cancer. The company's CIZ1B biomarker test identifies a stable plasma biomarker highly correlated with early-stage disease, offering an alternative to imaging or biopsy procedures. Cizzle's test…
Novel peptide therapeutics targeting obesity and type 2 diabetes
Dia Beta Labs is a preclinical-stage biotechnology company developing first-in-class therapeutic peptides for metabolic disease. Spun out of the Diabetes Research Group at Ulster University, the company is advancing three peptide candidates that act on hormone receptors to preserve insulin-producing pancreatic…
Clinical-stage precision oncology developing first-in-class TACC3 inhibitor therapeutics
Coiled Therapeutics is a UK-listed, clinical-stage oncology company developing precision cancer therapeutics against structurally complex, previously undruggable targets. Its lead candidate, AO-252, is a first-in-class, orally administered small molecule inhibitor of TACC3 currently in Phase I trials for advanced…
Long-read RNA sequencing platform for cancer biomarker discovery and diagnostics
Wobble Genomics is a Scottish biotechnology company developing long-read RNA sequencing technologies for biomarker discovery and cancer diagnostics. Its core platform combines a biochemical method to enrich rare and low-abundance full-length RNA transcripts, with a bioinformatics pipeline for novel transcript…
Non-endoscopic molecular diagnostics for early oesophageal cancer detection
Cyted Health is a gastrointestinal molecular diagnostics company developing minimally invasive testing for early detection and monitoring of oesophageal pre-cancer and cancer. Its platform combines a swallowable capsule sponge cell collection device with AI-driven biomarker molecular assays to detect Barrett's…