Biotechnology companies apply biological science to develop products, services and technologies that address challenges in healthcare, agriculture, industry and environmental sustainability.
This category includes companies working on:
Browse 360 UK biotechnology companies below.
Molecular and digital biomarkers for personalised cancer treatment
Oxford Cancer Biomarkers is a precision oncology diagnostics company developing molecular and digital pathology tests to support personalised cancer treatment. Its pharmacogenomic assays assess inherited variants associated with fluoropyrimidine chemotherapy toxicity, while its algorithm-driven pathology tools analyse…
Complex molecule synthesis and chemistry-driven cancer drug discovery
New Path Molecular Research is a Cambridge-based chemistry company spun out from the laboratory of Professor Steve Ley at the University of Cambridge. The company specialises in the synthesis of complex functional molecules, including natural products, macrocycles and peptides, using flow chemistry and…
Galectin-3 targeted small molecule therapeutics for cancer and fibrosis
Galytx is a University of Liverpool spin-out developing small molecule therapeutic drugs that target galectin-3, a protein closely associated with cancer, fibrosis and inflammatory disease. The company's portfolio includes a repurposed clinical-stage asset with an established safety record, alongside pre-clinical…
Molecular assay platform for genomic profiling in cancer diagnostics
Biofidelity is a Cambridge-based genomic technology company developing molecular assays for cancer biomarker detection in tissue and liquid biopsy samples. Its proprietary platform enables ultra-sensitive detection of somatic mutations at low variant allele fractions using a simplified four-step qPCR workflow, without…
Rapid blood biomarker test for pre-hospital stroke triage
Upfront Diagnostics is a diagnostic biotechnology company developing rapid blood tests for emergency stroke triage. Its lateral-flow assay measures D-dimer and glial fibrillary acidic protein (GFAP) from a finger-prick sample, providing results in under ten minutes to support identification of suspected…
Non-invasive vaginal sampling for gynaecological disease
Ellele Health is a medical research company developing a minimally invasive vaginal sampling device and associated downstream assays for the detection and management of gynaecological conditions. Using a proprietary biospecimen collected from the vaginal wall, the company applies genetic, epigenomic, and microbial…
Gut microbiome tests predicting biologic drug response in IBD
AlphaBiomics is a precision medicine company developing diagnostics that analyse the gut microbiome to guide treatment decisions. Its lead test uses a stool sample collected at home and machine learning analysis of microbial sequencing data to predict which patients with inflammatory bowel disease are likely to…
Systems biology platform for brain disease drug discovery and repurposing
BRAINCURES is a computational biotechnology company applying a systems biology approach to drug discovery for brain diseases, including Alzheimer's disease, depression, epilepsy, pain and schizophrenia. Its platform maps molecular relationships between compounds, genes and diseases, drawing on its own model of the…
Sperm DNA fragmentation diagnostics for male fertility assessment
Examen is a Belfast-based diagnostics company specialising in male reproductive health. Its proprietary assay-based technology measures single-strand and double-strand sperm DNA breaks to provide a clinically actionable assessment of male fertility beyond conventional semen analysis parameters. Tests are…
Human ovarian cell models and multi-omics drug discovery
OvartiX is a Cambridge biotechnology company developing drug-discovery tools and therapeutic programmes for ovarian and reproductive health. Its platform combines human multi-omics datasets, machine learning and engineered two- and three-dimensional ovarian cell models to identify and validate disease targets. Founded…
Single-cell somatic mutation analysis for measuring biological ageing
AgeCurve is a geroscience company developing diagnostics that measure biological ageing at the level of individual cells. Its approach analyses the burden and lineage structure of somatic mutations in single cells, combining genotype with cellular phenotype data through machine learning to estimate how far ageing has…
Nanoparticle platform for targeted genetic medicine delivery
ViaNautis is a nanomedicine company developing a polymer nanoparticle platform for the targeted intracellular delivery of genetic therapeutic payloads across difficult-to-penetrate biological barriers. The platform is designed to encapsulate a broad range of genetic cargoes and guide them to specific tissues and cell…
Controlled-release orthobiologics for spinal fusion and bone repair
Locate Bio is a clinical-stage biotechnology company developing a portfolio of orthobiologic products for musculoskeletal surgery. Its proprietary Programmed Drug Release platform encapsulates recombinant proteins within biodegradable polymer scaffolds to enable controlled, extended-release delivery. Lead product…
Bispecific antibody platform for cancer immunotherapies
F-star Therapeutics is a clinical-stage biotechnology company developing tetravalent bispecific antibodies for cancer and other serious diseases. Its proprietary platform creates antibodies with four binding sites that simultaneously target two different antigens, enabling focused immune activation in the tumour…
DNA-based gene therapy platform for intercellular therapeutic gene delivery
Bitrobius Genetics is a UK biotech developing a novel DNA-based gene therapy platform technology designed to deliver functional copies of mutated genes to cells within a target tissue or organ. Its platform is based on the principle of DNA replication and intercellular transmission, aiming to achieve broad tissue…
Rapid molecular tests for industrial and bioprocess contamination
Fuse Diagnostics develops rapid, low-cost molecular tests for use at the point of need. Its disposable tests use proprietary amplification chemistry to detect pathogens and contaminants in under ten minutes, without requiring specialist laboratory infrastructure. The company targets applications in bioprocessing, cell…
Pre-competitive biologics drug discovery platforms and services for partners
Alloy Therapeutics UK is the Cambridge-based research operation of Alloy Therapeutics, a biotechnology platform company providing pre-competitive drug discovery technologies and services across antibody, TCR, genetic medicine, cell therapy, peptide, and drug delivery modalities. The company offers both discovery…
OrganoMaps AI and multi-omics modelling for drug discovery
AI VIVO is a Cambridge biotechnology company combining machine learning and multi-omics data to model disease biology and drug responses. Its OrganoMaps approach links molecular measurements with tissue and organ-level physiological networks, supporting analysis of therapeutic targets and mechanisms of action. The…
Automated bioreactor platform for GMP cell therapy manufacturing
Aglaris is a developer of automated cell manufacturing systems for advanced therapy medicinal products. Its flagship platform integrates real-time process monitoring, single-use culture cartridges, and GMP-compliant controls to enable reproducible production of CAR-T cells, mesenchymal stem cells, and other cell types…
Metal-based antimicrobial drugs and antibiofilm coating compounds
MetalloBio is a University of Sheffield spin-out developing metal-based antimicrobial compounds against drug-resistant bacterial infections. Its KLS-1 series includes investigational antibacterial candidate KLS-116, designed to act against multidrug-resistant pathogens and biofilms. The KLS-2 series is being developed…