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Directory

Drug Discovery Companies in the UK

Drug discovery companies identify, validate and develop new therapeutic candidates for the prevention and treatment of disease. The sector combines biology, chemistry, data science and clinical expertise to bring new medicines from concept to clinic.

This category includes companies working on:

  • Target identification and validation
  • Screening and lead optimisation
  • Small molecule and biologic discovery
  • Computational and AI-driven drug discovery
  • Translational research and therapeutic development

Browse 422 UK drug discovery companies below.

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Drug Discovery
Showing 169–180 of 422
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Tangram Therapeutics

Greater London

AI-powered RNAi drug discovery company developing hepatic medicines

Tangram Therapeutics is a biotechnology company combining artificial intelligence and RNA interference to discover and develop novel medicines. Its proprietary chemistry platform…

Biotech
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Ikarovec

East of England

Bicistronic AAV gene therapies for retinal disease

Ikarovec is a near-clinical-stage gene therapy company developing bicistronic AAV-based therapeutics for vision-threatening retinal diseases. Its proprietary platform combines two…

Biotech
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AMR Bio

Greater London

Phase III-ready antimicrobial advancing post-surgical infection prevention

AMR Bio is a clinical-phase biotechnology company advancing XF-73, a Phase III-ready topical antimicrobial using an ultra-rapid antibacterial mechanism to prevent post-surgical…

Biotech
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Mosaic Therapeutics

East of England

Targeted oncology combination therapies in biomarker-defined cancer populations

Mosaic Therapeutics is a Cambridge biotech developing targeted combination therapies for cancer. Its proprietary platform integrates genome-scale CRISPR screening, high-throughput…

Biotech
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Sitala Bio

East of England

Anti-inflammatory drugs for neurodegenerative disease

Sitala Bio is a Cambridge-based biotech developing small molecule drugs that target chronic neuroinflammation in conditions such as Parkinson's and Alzheimer's disease. The…

Biotech
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PentaBind

Greater London

AI-designed aptamer therapeutics for undruggable targets

PentaBind is a TechBio company using generative AI to design aptamers with drug-like properties for targets that are inaccessible to conventional modalities. Its platform combines…

Biotech
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Dominion Biotech

North West England

Patient-derived cell models and assays for oncology drug discovery

Dominion Biotech is a Cheshire-based biotechnology company developing patient-derived cell (PDC) models and assays to support oncology drug discovery and development. Working in…

CROBiotech
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Exciting Instruments

Yorkshire

Benchtop single-molecule fluorescence instruments for life science research

Exciting Instruments develops accessible benchtop single-molecule fluorescence spectroscopy instruments and cloud-based analysis software. Its system enables researchers to…

Instruments & EquipmentSoftware
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Quotient Sciences

Midlands

Integrated drug development, formulation and Phase I clinical services

Quotient Sciences is a contract research, development and manufacturing organisation providing integrated drug development services to pharmaceutical and biotech companies. Its…

CDMOCRO
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Platelet Services

Midlands

Pre-clinical platelet function testing for drug discovery and safety

Platelet Services is a contract research organisation specialising in pre-clinical platelet function testing for pharmaceutical and biotechnology clients. The company provides…

CRO
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Pheon Therapeutics

Greater London

Clinical-stage antibody-drug conjugate specialist targeting solid tumours

Pheon Therapeutics is a clinical-stage biotechnology company developing a pipeline of antibody-drug conjugates for the treatment of solid tumours. The company combines monoclonal…

Biotech
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Macomics

Scotland

Macrophage-targeting immuno-oncology therapies for solid tumours

Macomics is an immuno-oncology company developing precision medicines that modulate tumour-associated macrophages to enhance immune responses against cancer. Founded by University…

Biotech
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