Discover life science companies across the East of England, including biotechnology firms, CROs, research organisations and innovation hubs.
Custom gene synthesis and molecular biology reagents for laboratory research
NBS Biologicals is a UK manufacturer and supplier of reagents, kits, biochemicals and labware for the laboratory research industry, combining its own expanding NBS product range with representation of major international brands. Through its parent company, the business offers custom gene synthesis and oligonucleotide…
Scientific informatics and cheminformatics software for R&D
Dotmatics is a scientific informatics software company connecting chemical, biological and experimental data across research and development. Its Vortex platform supports chemical data visualisation, structure-aware analysis and structure–activity relationship exploration. Its wider portfolio includes electronic…
Structural chemistry database and software for drug discovery
The Cambridge Crystallographic Data Centre (CCDC) is a non-profit organisation that curates and distributes the Cambridge Structural Database (CSD), the world's repository of experimentally determined small-molecule organic and metal-organic crystal structures, containing over one million entries. Alongside the…
Small molecule MMR inhibitors to enhance tumour immunogenicity
NeoPhore is a UK immuno-oncology company developing first-in-class small molecule inhibitors of the DNA mismatch repair pathway. By transiently blocking MMR, the company's compounds render tumours MMR-deficient and immunogenic, generating neoantigens that stimulate immune responses against cancer. The approach aims to…
AI genomics for drug target discovery
OutSee is a genomics and drug discovery company using proprietary AI technology to identify and validate novel therapeutic targets. Its core platform applies predictive algorithms to large-scale genomic datasets to uncover disease-modulating biological mechanisms, complementing traditional analysis methods. OutSee…
Global licensing and commercialisation of established branded pharmaceutical medicines
Pharmanovia is a specialty pharmaceutical company that acquires, licenses and commercialises established branded medicines, extending their lifecycle for patients worldwide. The company's portfolio spans more than 25 medicines across endocrinology, neurology, cardiovascular and oncology, built through strategic…
AI vision systems for surgical workflows and cell therapy manufacturing
Appraiseye develops AI-powered vision systems for life sciences and healthcare applications across two platforms. Its operating theatre intelligence platform provides real-time instrument tracking, tray utilisation analytics and sterile processing optimisation for surgical departments. Its platform applies AI-guided…
Computational DNA design for durable genetic medicines
Houdini Bio is an early-stage biotechnology company using computational synthetic biology to redesign DNA for improved performance in genetic medicines. The company is developing approaches to enhance the durability and scalability of gene expression, with potential applications across gene therapies and DNA-based…
ENTECH platform for cell perturbation and AI target discovery
Aparna Bio develops technologies for generating biologically relevant cell-perturbation data to support drug target discovery. Its ENTECH platform is being engineered to deliver experimental perturbation reagents into primary human cells and other disease-relevant models, where conventional delivery methods can be…
Semiconductor biochips and instruments for high-throughput DNA synthesis
LinkZill is a semiconductor technology company developing instruments and consumables for high-throughput DNA synthesis and molecular research. Its thin-film transistor (TFT) biochips use electronic control of electrochemical reactions to manufacture oligonucleotide microarrays and DNA pools. The company supplies…
Modular automated RNA manufacturing platform
Centillion is a UK biotech company whose platform integrates synthesis, purification, and formulation stages using continuous flow chemistry to produce mRNA and self-amplifying RNA at research and production scale. The platform supports process development through to regulatory-ready CMC packages and is available as a…
AI-guided personalised mRNA cancer vaccine development
Genevation is a biotechnology company developing personalised mRNA cancer vaccines using AI-assisted tumour neoantigen identification. Its platform analyses tumour sequencing data to select patient-specific targets and combines computational vaccine design with cell-free RNA manufacturing. The company reports…
Microcarrier platform enabling adherent cell screening for drug discovery
Semarion is an advanced materials engineering company developing microcarriers for adherent cell assays in drug discovery workflows. Fabricated using microchip-style microfabrication techniques, Semarion develops magnetically steerable cell carriers that enable small colonies of adherent cells to be moved, pooled, and…
AI-guided plant biosynthesis platform for novel therapeutic compounds
HotHouse Therapeutics is a drug discovery platform company that engineers plants as sustainable biofactories for pharmaceutical compound production. Using AI to design and optimise biosynthetic pathways, it produces both natural and new-to-nature molecules via transient and stable plant expression systems capable of…
Tissue-based endometriosis models for therapeutic target discovery
Cyclana Bio is a biotechnology company developing human tissue-based models to investigate endometriosis and identify therapeutic targets. Its research combines endometrial tissue biopsies and menstrual fluid samples with molecular profiling and three-dimensional disease models, focusing on extracellular matrix…
KnotBody therapeutics for ion channel and GPCR diseases
Maxion Therapeutics is a biotechnology company developing a pipeline of KnotBody therapeutics for diseases driven by ion channel and G protein-coupled receptor dysfunction. The platform combines naturally occurring mini-proteins with antibodies to generate potent, selective and long-acting biologics against target…
Gene editing tools, cell lines and genomic reagents for life science research
Horizon Discovery is a Cambridge-based life sciences company supplying gene editing and gene modulation tools, services, and engineered cell lines to pharmaceutical, biotechnology, and academic customers. Its portfolio includes CRISPR and RNAi reagents, isogenic cell line pairs modelling disease-associated mutations,…
Engineering biology research for pollution removal and resource recovery
Environmental Biotechnology Innovation Centre is a Cranfield University-led research partnership applying engineering biology to environmental monitoring, pollution removal and resource recovery. Its programme develops engineered microorganisms, enzymes, biofilms and biosensors for challenges including PFAS…
RNA sequencing liquid biopsy for cardiovascular and complex disease screening
MultiplAI Health is a Cambridge biotech developing a whole-blood RNA sequencing test for early screening of cardiovascular and other complex diseases. Its platform combines transcriptomic profiling of blood samples with a patented data transformation process and proprietary deep learning algorithms to generate…
Purpose-built technology and life science campus near Cambridge
TTP Campus is a bespoke research and technology campus located in Melbourn, Cambridgeshire, developed and operated by TTP Group. The campus houses TTP plc alongside a growing cluster of spinout companies. Facilities include CL2 wet laboratories, chemistry labs, low-vibration suites for laser and optics work, advanced…