Discover life science companies across the East of England, including biotechnology firms, CROs, research organisations and innovation hubs.
CreaTap antibody engineering for improved solid tumour penetration
Creasallis is a biotechnology company developing antibody engineering technologies intended to improve drug delivery into solid tumours. Its patented CreaTap platform modifies therapeutic antibodies to promote deeper penetration into tumour tissue. The approach is under development for monoclonal antibodies,…
Cambridge innovation centre for science and technology businesses
St John's Innovation Centre is a business incubator supporting science, technology and research-led companies with flexible workspace and business development services. Established by St John's College, University of Cambridge, it opened in 1987 within St John's Innovation Park. The centre accommodates early-stage and…
Lentiviral gene therapy developer for tumours and rare diseases
Santo Therapeutics develops in vivo lentiviral gene therapies for cancer and rare genetic disorders. Its proprietary vector platform supports programmes including ST002, an NF2 gene-replacement therapy for NF2-related schwannomatosis. The company announced the start of an investigator-initiated clinical trial of ST002…
British generic medicine manufacturer supplying UK and European healthcare markets
Bristol Laboratories is a British pharmaceutical company developing, manufacturing, marketing and distributing generic medicines across the UK and Europe. The company manufactures a wide range of pharmaceutical products spanning urology, pain relief, antibiotics and respiratory conditions, alongside an expanding…
Omics interpretation and mechanism-of-action analysis for agricultural biotechnology
TraitSeq is an agricultural bioinformatics company analysing transcriptomic and other omics datasets to explain biological responses to crop inputs. Its platform combines statistical analysis with species-specific knowledge graphs, published literature and AI-assisted interpretation to identify molecular pathways,…
T cell-engaging multispecific antibody fragments for solid tumours
Crescendo Biologics is a clinical-stage biopharmaceutical company developing multispecific therapeutics based on fully human single-domain antibody fragments engineered for enhanced tumour penetration and selective T cell activation within the tumour microenvironment. Its lead programme is in Phase 1b clinical trials…
Molecular farming platform producing specialty proteins from crop leaves
Kyomei is a biotechnology company developing a molecular farming platform that genetically engineers crop plants to produce high-value specialty proteins in their leaves. The company extracts these proteins from agricultural leaf waste that would otherwise be discarded at harvest. Kyomei's ingredients target food…
Genotyping reagents and assay solutions
3CR Bioscience is a UK-based life science company developing PCR-based genotyping reagents, assay kits and related instrumentation for molecular biology and genomics applications. The company provides SNP and indel genotyping chemistries, DNA extraction products and custom assay development services supporting…
Sequencing kits for genome-wide off-target analysis of gene editing
Broken String Biosciences is a genomics company that develops tools for measuring the safety of genome editing. Its platform uses next-generation sequencing to map DNA breaks and editing intermediates across the genome, allowing developers to detect and quantify on-target and off-target edits made by nucleases and…
Open innovation life sciences campus co-located with GSK
Stevenage Bioscience Catalyst (SBC) is a not-for-profit open innovation campus and the UK's first biomedical catalyst, established in 2012 through joint funding from GSK, Wellcome and Innovate UK. Co-located with GSK's UK R&D facility, the campus hosts over 40 life science companies alongside the Cell and Gene Therapy…
AAV gene therapy targeting the seizure focus in refractory epilepsy
Focalis Bio is a biotechnology company developing gene therapies for focal refractory epilepsy, a condition in which seizures arise from a specific brain region and do not respond to antiseizure medicines. Its lead programme, EPY201, is an AAV9-based gene therapy delivered locally via catheter directly to the…
Neuroactive therapeutics through genetic engineering of fungi and plants
Empyrean Neuroscience is a biopharma company that uses genetic engineering of fungi and plants to develop small molecule therapeutics for neuropsychiatric and neurologic disorders. Using CRISPR/Cas9 and proprietary transformation technologies, the platform enables precise modulation of neuroactive compound production.…
ML-enabled nanoparticle delivery platform for targeted therapeutics
Vector Bioscience is a University of Cambridge spin-out developing a machine learning-enabled drug delivery platform based on metal-organic framework nanoparticles. The technology provides cargo-agnostic, targeted delivery of oligonucleotides and small molecules with controlled release, initially focused on…
Cloud-based informatics platform for drug discovery data management
Collaborative Drug Discovery (CDD) is a software company providing a cloud-based informatics platform for drug discovery research. Its flagship product enables scientists to register compounds, manage bioassay and chemical data, track inventory and capture experiments through an integrated electronic laboratory…
Synthetic biology platform for sustainable biological textile dyeing
Colorifix is a UK biotechnology company applying synthetic biology to develop a biological dyeing process for the textile industry. The company engineers microorganisms to produce, deposit and fix pigments directly onto fabric, eliminating the need for toxic chemicals and reducing water and energy consumption compared…
Preclinical CRO delivering integrated drug discovery and development services
Selvita is a contract research organisation providing integrated drug discovery and development services to pharmaceutical and biotechnology companies. The company supports projects from target validation through preclinical candidate nomination, with expertise in medicinal chemistry, pharmacology, DMPK and protein…
GC–MS instrumentation and software for analytical research
SepSolve is an analytical instrumentation and software company supplying gas chromatography and mass spectrometry platforms for research laboratories. Its technologies include two-dimensional GC separation, time-of-flight mass spectrometry, automated sample introduction and software for resolving complex chemical…
Integrated outsourced drug discovery and development platform
RxCelerate is a contract research organisation providing fully integrated drug discovery and development services to pharmaceutical and biotech companies. Based at Babraham Research Campus, the company offers end-to-end programme delivery spanning computational design, antibody discovery, medicinal chemistry, in vitro…
AI-driven drug discovery targeting necrosis and age-related disease
LinkGevity is a preclinical-stage biotechnology company developing anti-necrotic therapeutics for age-related and degenerative diseases. Founded in 2023 and based at Babraham Research Campus, the company's proprietary Blueprint Theory of Ageing identifies necrosis as a key driver of biological decline, informing its…
Small-molecule anti-biofilm add-on therapy for antibiotic-resistant urinary tract infections
BioTryp Therapeutics is a UK-based drug discovery company developing small-molecule therapies that inhibit bacterial biofilm formation. The company's lead programme is an oral add-on therapy designed to be used alongside existing antibiotics, targeting a bacterial protein conserved across more than 85 species to…