Discover life science companies in Manchester, including biotechnology innovators, CROs and research organisations.
National innovation centre accelerating drug discovery
Medicines Discovery Catapult (MDC) is an independent, not-for-profit national innovation centre that supports UK medicines discovery organisations across the full drug discovery pipeline. MDC provides access to specialist laboratory technologies, computational and AI-driven tools, translational R&D expertise, and…
DNA-based gene therapy platform for intercellular therapeutic gene delivery
Bitrobius Genetics is a UK biotech developing a novel DNA-based gene therapy platform technology designed to deliver functional copies of mutated genes to cells within a target tissue or organ. Its platform is based on the principle of DNA replication and intercellular transmission, aiming to achieve broad tissue…
Microbial soil amendments for crop drought resilience
CroBio is an agricultural biotechnology company developing living microbial soil amendments to improve crop drought resilience. Its microorganisms use plant root exudates to produce bacterial cellulose, creating a water-retentive matrix around roots that can also help retain nutrients. The technology is progressing…
Isothermal molecular diagnostics and assay development services
Simplex Molecular is a biotechnology company developing instrument-free nucleic acid testing technology alongside molecular biology research services. Its proprietary isothermal amplification chemistry operates at room temperature and is being developed into a portable, multiplexed diagnostic platform with…
Life science membership organisation for the North of England
Bionow is a not-for-profit membership organisation supporting the biomedical, pharmaceutical and life sciences sectors across Northern England. It provides members with procurement benefits, business development support, funding guidance, recruitment services and access to a network of companies, universities and NHS…
Patient-derived cell models and assays for oncology drug discovery
Dominion Biotech is a Cheshire-based biotechnology company developing patient-derived cell (PDC) models and assays to support oncology drug discovery and development. Working in partnership with cancer hospitals and academic collaborators, the company builds a diverse bank of PDC models reflecting the genetic…
Next-generation CAR T-cell therapies for solid tumours
ImmunoKey is a seed-stage biotechnology company developing CAR T-cell therapies designed to overcome the barriers limiting efficacy in solid tumours. Its proprietary platform enables multi-antigen targeting while minimising off-tumour toxicity, supported by complementary technologies to enhance T-cell persistence and…
Molecular diagnostic PCR, dPCR and NGS kits for clinical laboratories
TRUPCR Europe develops and supplies molecular diagnostic kits and reagents for clinical and research laboratories. Its portfolio includes real-time PCR, digital PCR and next-generation sequencing assays for oncology, haematological malignancies, infectious diseases and antimicrobial resistance. Products also include…
In vivo safety pharmacology and cardiovascular preclinical testing
Vivonics Preclinical is a contract research organisation providing in vivo safety pharmacology studies for biotechnology and pharmaceutical drug development teams. Its services assess how experimental compounds affect vital organ function, particularly cardiovascular physiology, using telemetry, electrocardiography,…
Nonclinical safety toxicology and ion channel screening services
ApconiX is a nonclinical safety consultancy and ion channel laboratory supporting drug discovery and development programmes. The company provides project toxicology, DMPK support, target safety assessments, study outsourcing and monitoring, and specialist subject matter expertise across disciplines including safety…
Immunotherapeutics targeting drug-resistant bacterial infections
Centauri Therapeutics is a clinical-stage immunotherapy company developing treatments for life-threatening infectious diseases using its proprietary platform. The technology uses synthetic bifunctional molecules that recruit and redirect naturally occurring anti-glycan antibodies to target pathogens, engaging both…
Specialist biomarker and bioanalytical CRO for clinical drug development
Synexa Life Sciences is a specialist contract research organisation providing biomarker and bioanalytical laboratory services to global biopharmaceutical companies. The company develops, validates, and delivers custom assays supporting clinical trials and translational studies, with expertise spanning LC-MS/MS…
Life sciences and technology innovation campus in Manchester
Manchester Science Park is a life sciences and technology innovation campus in Manchester's Oxford Road Corridor, adjacent to the University of Manchester and Manchester University NHS Foundation Trust. It is managed by Bruntwood SciTech on behalf of Manchester Science Partnerships. It provides office and laboratory…
Small molecule drug discovery focused on fibrosis and oncology
Redx Pharma is a clinical-stage biotech developing novel small molecule therapeutics for fibrotic disease and cancer. Its pipeline is anchored by zelasudil, a selective ROCK2 inhibitor in clinical development for idiopathic pulmonary fibrosis and other fibrotic indications, and zamaporvint, a Porcupine inhibitor…
Integrated drug discovery, development and GMP manufacturing CRO
Concept Life Sciences is a contract research organisation delivering integrated drug discovery, development and GMP manufacturing services across facilities in Chapel-en-le-Frith, Edinburgh, Dundee and Sandwich. Its capabilities span medicinal chemistry, translational biology, ADME/DMPK, toxicology and GxP-compliant…
MALDI-TOF mass spectrometry instruments for clinical microbial identification
Ascend Diagnostics is a developer of MALDI-TOF mass spectrometry systems for high-throughput clinical diagnostic laboratories. Its platform identifies bacteria and other microorganisms from patient samples by measuring their characteristic protein profiles and matching them against a microbial reference database,…
Small molecule drug discovery platform focused on immuno-inflammation
C4X Discovery (C4XD) is a UK drug discovery company developing small molecule drug candidates using its proprietary computational and structural chemistry platform. It applies enhanced candidate molecule design and patient stratification capabilities to generate drug candidates across immuno-inflammatory disease…
Liquid biopsy platform for isolating circulating tumour cells
Vortex Biosciences develops liquid biopsy technology for isolating circulating tumour cells from whole blood. Its automated, non-contact approach is designed to recover intact, viable cells that can be studied after collection. Preserving cell viability is important for molecular and functional analysis, rather than…
Mass spectrometry and analytical instruments for laboratory research
LECO Instruments UK is a UK subsidiary of an international manufacturer of analytical laboratory instruments. It supplies gas chromatography, time-of-flight mass spectrometry and elemental analysis systems, with applications in metabolomics, protein analysis, pharmaceutical testing and other analytical disciplines.…
Fluorinated building blocks and fine chemicals for research and pharma
Apollo Scientific is a manufacturer and supplier of fine chemicals for research and pharmaceutical development, specialising in aromatic, heterocyclic and fluorinated building blocks. It holds a large stock of building blocks and intermediates for rapid dispatch, alongside reagents for life science research. The…