Discover life science companies in North East England, including biotechnology innovators, research institutes and specialist service providers.
Cell-based quality control materials for immunohistochemistry and ISH
HistoCyte Laboratories is a developer and manufacturer of cell-based quality control materials for immunohistochemistry and in situ hybridisation. Its products use proprietary cell line processing technology to produce formalin-fixed, paraffin-embedded control slides and blocks with reproducible, well-characterised…
Clinical-stage antibody-drug conjugate developer for cancer
Iksuda Therapeutics is a clinical-stage biotechnology company developing antibody-drug conjugates for difficult-to-treat cancers. Its platform combines stable bioconjugation chemistry with tumour-selective payload activation to improve therapeutic index. Clinical programmes include IKS014, a HER2-targeting ADC, and…
Novel small-molecule therapeutics for neurodegenerative diseases
Nevrargenics is a UK-based biotech company developing novel small-molecule therapeutics for neurodegenerative diseases. Spun out of Durham University and built on research collaboration with the University of Aberdeen, the company uses a patented library of dual-activity retinoic acid receptor modulators designed to…
Oral iron deficiency therapy for adults across multiple indications
Shield Therapeutics is a commercial-stage specialty pharmaceutical company focused on iron deficiency. Its lead product, Accrufer/Feraccru (ferric maltol), is an oral iron therapy approved for adults with iron deficiency with or without anaemia. The product is commercialised in the US with Viatris and licensed to…
C. elegans whole-organism platform for preclinical drug and compound screening
Magnitude Biosciences Limited is a contract research organisation providing preclinical drug discovery and compound screening services using Caenorhabditis elegans as a whole-organism model. Its proprietary biophotonics platform enables automated, high-throughput, non-invasive monitoring of health and lifespan metrics…
Contract research using in vitro models of the human gut
Aelius Biotech is a contract research organisation using laboratory models of the human digestive tract to study drugs, nutritional products and functional foods. Its animal-free systems help customers explore how formulations behave during digestion and provide evidence for product development. The company works with…
Specialist distributor of transplant diagnostics and molecular biology products
VH Bio is a specialist distributor of life science research and diagnostic products serving the United Kingdom and Republic of Ireland. The company focuses on four areas: transplant and HLA diagnostics, molecular biology, immunology, and cell biology. Its portfolio of approximately 10,000 products is sourced from…
Enzymatic synthetic DNA manufacture for gene therapy and molecular biology
NunaBio is a specialist DNA synthesis company developing a cell-free enzymatic platform for scalable production of synthetic DNA, including long oligonucleotides, whole genes and DNA fragments. Its technology avoids the plasmid and primer-dependent steps that constrain conventional phosphoramidite chemistry, enabling…
Ultra-sensitive DNA detection platform
InvenireX is developing a nucleic acid detection platform that uses programmable DNA nanostructures captured within microfluidic chips, read by a proprietary AI-powered imaging system. The technology detects genetic markers at concentrations below the threshold of conventional methods such as PCR, with potential to…
AI-powered ultrasound analysis software for endometriosis detection
Revela is a medical software company developing machine learning tools to assist in the diagnosis of endometriosis via analysis of ultrasound scans. The software automatically identifies subtle imaging signs associated with endometriosis and returns a structured report to the reviewing clinician, targeting earlier…
Engineered bacterial protein polymers for cell culture and cultivated meat
MarraBio is a biotechnology company developing engineered Caf1-based protein polymers as xeno-free, thermostable alternatives to extracellular matrix proteins and growth factors used in mammalian cell culture. Its proprietary platform enables scalable, cost-effective production of multifunctional materials that…
Living building materials and microbial construction biotechnology research
Hub for Biotechnology in the Built Environment is a Newcastle and Northumbria University research collaboration developing biologically enabled building materials and environmental technologies. Its work spans microbial mineralisation, self-healing construction materials, mycelium-based structures, building…
Portable multiplex PCR molecular diagnostic platform for point-of-care use
QuantuMDx is a medical technology company developing a battery-operated, handheld molecular diagnostic system that delivers multiplex PCR results from a single-use reagent cassette within 35 minutes. Designed for point-of-care and resource-limited settings, the CE-IVD marked device supports assays for respiratory…
Rapid 3D-printed microfluidic chips, manifolds and lab devices
Rapid Fluidics is a UK engineering company that designs and manufactures custom microfluidic devices using proprietary 3D-printing techniques, delivering prototype parts in days rather than weeks. Its capabilities include biocompatible chips, pneumatic manifolds, embedded sensors and electronics, anatomical…
Hypothermic gel preservation technology for shipping cells
Atelerix is a biotechnology company supplying hydrogel-based cell and tissue preservation products that eliminate the need for cryogenic cold chain logistics. Its patented alginate encapsulation technology maintains cell viability at ambient temperatures for up to fourteen days, enabling the shipment of cells,…
Ultrasensitive multiplex biomarker services for clinical studies
Aeirtec is a contract research organisation providing clinical study biomarker measurement services to the biopharma industry. Its patented immobilised-bead immunomultiplex assay technology enables high-sensitivity quantification of protein biomarkers from clinical samples at femtogram concentrations. Services include…
Science and technology park with three national catapult centres
NETPark is a science, engineering and technology park located in Sedgefield, County Durham. The campus provides laboratory, cleanroom and office space for companies from incubation through to scale-up manufacturing. NETPark is the only UK science park with three National Catapult Centres on site and works in close…
Chemistry-led CRO and CDMO for pharmaceutical and diagnostics R&D
High Force Research is an independent chemistry CRO and CDMO providing synthetic chemistry, process development, and GMP manufacturing services to the pharmaceutical, biotech, and diagnostics industries. Services span route design, complex synthesis, scale-up, and analytical development through to regulatory-grade…
Non-invasive mitochondrial DNA damage testing for skin health research
Skin Life Analytics is a biotechnology company providing PCR-based testing services that quantify mitochondrial DNA damage in skin using non-invasive swab sampling. The technology detects molecular markers of skin ageing, UV damage, and environmental stress before visible signs appear. Services include direct testing…
Macromolecular crowding supplements for scalable cell culture
milieu.bio is a UK supplier of cell-culture media additives for biopharmaceutical research, cell therapy and cellular agriculture. It commercialises CityMix and CytoBoost, macromolecular crowding formulations designed to support cell expansion and extracellular matrix production while reducing reliance on costly media…