Small molecule drug companies develop low-molecular-weight medicines designed to interact with specific biological targets. These compounds can often enter cells and may be formulated as oral or other conventional dosage forms across a wide range of therapeutic areas.
This category includes companies working on:
Browse 202 UK small molecule drug companies below.
Synthetic plant metabolites for osteoarthritis and age-related disease
AKL Therapeutics is a privately held UK pharmaceutical company developing APPA, a patented oral investigational medicine combining two synthetic plant metabolites that act…
Autophagy-enhancing small molecule drugs for neurodegeneration and rare disease
Samsara Therapeutics is a drug discovery company developing first-in-class small molecule therapeutics that restore autophagy, the cellular process of degrading and recycling…
Next-generation targeted protein degradation therapeutics
Amphista Therapeutics is a Cambridge-based biopharmaceutical company developing next-generation targeted protein degradation medicines. Its proprietary platform generates…
Cyclic peptide screening platform for first-in-class cancer drugs
Curve Therapeutics is a drug discovery company using its proprietary platform to identify first-in-class small molecule therapeutics against targets that have been difficult to…
Phosphoproteomics platform for kinase activity profiling and precision oncology
Kinomica is a UK precision medicine company developing phosphoproteomics technology for drug discovery and companion diagnostics. Its platform combines LC-MS/MS mass spectrometry…
Clinical trial supply, packaging and distribution services
Sharp Services is a contract development and manufacturing organisation providing clinical supply chain services for pharmaceutical and biotechnology companies. Operating from an…
Preclinical DMPK, bioanalysis and toxicology CRO
Pharmidex is a UK contract research organisation providing preclinical drug discovery and development services across DMPK, bioanalysis, toxicology, histology and in vitro ADME.…
AI platform integrating biology, chemistry and automation for drug discovery
Recursion is a clinical-stage biotechnology company using AI and robotic wet-lab automation to industrialise small molecule drug discovery. Its platform integrates phenomics,…
Native mass spectrometry platform for small molecule drug discovery
OMass Therapeutics is a biotechnology company developing small molecule therapeutics against membrane proteins, GPCRs, and intracellular complexes that have historically been…
Clinical-stage biopharma developing treatments for cancer and rare diseases
Biodexa Pharmaceuticals is a Cardiff-based clinical-stage biopharmaceutical company advancing a pipeline of proprietary drug formulations for diseases with high unmet need. Its…
Contract chemistry and manufacturing solutions for pharmaceutical and biotech research
Chemveda Life Sciences is a contract research and development organisation providing chemistry solutions to the pharmaceutical, biotechnology and agrochemical industries. The…
Ophthalmic therapeutics for presbyopia, cataracts, and geographic atrophy
Tenpoint Therapeutics is a clinical-stage biotechnology company developing therapeutics for age-related ocular diseases. Its pipeline comprises three programmes: BRIMOCHOL PF, a…