Small molecule drug companies develop low-molecular-weight medicines designed to interact with specific biological targets. These compounds can often enter cells and may be formulated as oral or other conventional dosage forms across a wide range of therapeutic areas.
This category includes companies working on:
Browse 202 UK small molecule drug companies below.
AI-powered drug design engine built on AlphaFold technology
Isomorphic Labs is an artificial intelligence company applying frontier AI to drug discovery, built on and beyond the Nobel Prize-winning AlphaFold protein structure prediction…
Formulation development CDMO for difficult pharmaceuticals
Agility Life Sciences is a contract development and manufacturing organisation specialising in pharmaceutical formulation development. Based in Stapleford, Nottingham, the company…
Fragment and structure-based drug discovery services
Vernalis (R&D) is a Cambridge-based contract drug discovery organisation specialising in fragment-based and structure-based drug discovery. The company integrates structural…
Small molecule drugs targeting astrocytes in neurodegenerative disease
AstronauTx is a clinical-stage UK biotech developing oral small molecule therapeutics for Alzheimer's disease and other neurodegenerative disorders. The company's approach targets…
Global generics and specialty pharmaceutical manufacturer headquartered in London
Hikma Pharmaceuticals is a multinational pharmaceutical company developing, manufacturing and marketing generic, specialty and branded medicines across injectable, oral and…
AI platform targeting chromosomal instability across cancer
Tailor Bio is a Cambridge-based biotechnology company developing an AI-driven precision medicine platform for cancers with chromosomal instability, a genomic phenomenon present in…
Small molecule therapies for cystic fibrosis and COPD
Enterprise Therapeutics is a clinical-stage biopharmaceutical company developing novel muco-regulatory therapies for respiratory diseases. Its lead programme ETD001 is a…
E3 ligase inhibitors stabilising tumour suppressor proteins
Outrun Therapeutics is a preclinical drug discovery company developing small molecule inhibitors of E3 ligase enzymes to stabilise tumour suppressor and other disease-relevant…
Specialist CRO for drug and agrochemical metabolite synthesis and characterisation
Hypha Discovery is a specialist contract research organisation supporting pharmaceutical and agrochemical companies worldwide. The company produces and purifies drug and…
DUB inhibitor therapeutics targeting mitophagy and degenerative disease
Mission Therapeutics is a clinical-stage biotechnology company developing first-in-class small molecule inhibitors of deubiquitylating enzymes to treat diseases driven by…
Small molecule GPR65 inhibitors restoring immune response in solid tumours
Pathios Therapeutics is a clinical-stage drug discovery company developing small molecule inhibitors of GPR65, a pH-sensing G protein-coupled receptor that drives…
Precision oncology drugs and vaccines for cold tumours
IngenOx Therapeutics Limited is a clinical-stage biopharmaceutical company developing precision oncology drugs and cancer vaccines for difficult-to-treat tumours. The company…