Small molecule drug companies develop low-molecular-weight medicines designed to interact with specific biological targets. These compounds can often enter cells and may be formulated as oral or other conventional dosage forms across a wide range of therapeutic areas.
This category includes companies working on:
Browse 202 UK small molecule drug companies below.
Synthetic glycan-targeted small molecules for next-generation immunotherapy
Anomer Bio is a biotechnology company developing synthetic monosaccharides and small molecule drugs that target glycans, the sugars coating cell surfaces that influence immune…
Cocrystal drug repurposing for oncology supportive care and fibrosis
Nuformix is a pharmaceutical development company using proprietary cocrystal technology to repurpose existing drugs for unmet medical needs in fibrosis and oncology. By…
Small molecule therapeutics targeting PDE4 enzymes in kidney disease
Mironid is a company developing first-in-class small molecule therapeutics for autosomal dominant polycystic kidney disease, one of the most common hereditary kidney disorders.…
Targeted oral drug delivery platform for cancer, CNS and respiratory disease
TRX Biosciences is a biotechnology company developing a targeted oral drug delivery platform, enabling therapies to reach specific organs, cells and tissues for cancer, central…
RNA-targeted drug discovery platform using machine learning
RevoNA Bio is a biotechnology company developing a high-throughput RNA biological platform for RNA-targeted drug discovery. The platform generates comprehensive RNA structural and…
Bioanalytical CRO for drug quantification across development stages
Alderley Analytical is a contract research organisation providing bioanalytical testing services across the drug development continuum, from discovery through preclinical safety…
Targeted therapies against extrachromosomal DNA in cancer
Econic Biosciences is a drug discovery biotech developing therapies that target extrachromosomal DNA, a circular form of DNA found outside normal chromosomes that drives oncogene…
Global pharma company in oncology, immunology, and neuroscience
Johnson & Johnson is a multinational pharmaceutical company with UK operations spanning commercial, medical affairs, and innovation activities. Its Innovative Medicine division…
Small molecule neuromodulators for neuropsychiatric disorders
Draig Therapeutics is a clinical-stage biotech developing small molecule drugs that modulate the glutamate and GABA neurotransmitter pathways to treat neuropsychiatric disorders.…
Academic cancer research institute and drug discoverer
The Institute of Cancer Research (ICR) is an independent research institute and member institution of the University of London, specialising in cancer biology, drug discovery,…
Biotech venture builder co-creating and scaling drug discovery companies
Molecule to Medicine (MTM) is a biotech venture builder that co-creates, builds, and scales drug discovery companies within a shared operational ecosystem, combining drug…
Solid form sciences and API development for drug candidates
Veranova's Cambridge site is a centre of excellence in solid form and particle engineering, operating under the Pharmorphix brand. The facility provides polymorph screening, salt…