Explore life science companies operating throughout South East England, including biotechnology firms, CROs and research organisations.
Cyclic peptide screening platform for first-in-class cancer drugs
Curve Therapeutics is a drug discovery company using its proprietary platform to identify first-in-class small molecule therapeutics against targets that have been difficult to address using conventional methods. The platform screens gene-encoded cyclic peptide libraries inside mammalian cells to identify functionally…
Next-generation viral vectors engineered for safer gene therapy delivery
Sandbox Bioscience is a biotechnology company developing next-generation viral delivery vectors for gene therapy. Founded by a team of virologists with extensive experience in gene therapy delivery systems and platform development, the company is engineering vectors designed to improve on existing market solutions…
Oncolytic virus platform for tumour-targeted cancer immunotherapy
Accession Therapeutics is a clinical-stage biotechnology company developing tumour-targeted immunotherapies based on its proprietary oncolytic virus platform. Designed for systemic delivery, the platform selectively replicates within cancer cells to generate therapeutic payloads locally at the tumour site. The…
Clinical-stage developer of oncolytic immunotherapies for cancer treatment
Replimune is the UK research and development site of Replimune Group, a clinical-stage biotechnology company developing oncolytic immunotherapies for cancer. Its platform uses genetically engineered herpes simplex viruses to selectively replicate within and destroy tumour cells, releasing tumour antigens and…
AI-powered dental X-ray diagnostic software
BeCertain develops AI-powered software for interpreting dental X-rays. Its machine learning models are trained on annotated radiograph datasets to help clinicians detect caries, periodontal disease and other oral abnormalities. The company is a joint spinout from King's College London and the University of Surrey, and…
Preclinical small-molecule therapeutics targeting a novel pathway in chronic pain
Sevenless Therapeutics is a preclinical biotechnology company developing small-molecule medicines for people with chronic pain that responds poorly to existing treatments. The company has identified a new target in pain signalling using computational and mathematical modelling approaches and is designing small…
Global medical technology company specialising in chronic condition management
Convatec is a global medical products and technologies company focused on chronic condition management. The group develops and manufactures advanced wound care dressings, ostomy care, continence care and infusion care products, including hydrofiber-based, antimicrobial and tissue-derived biomaterial wound dressings…
Full-service CRO delivering clinical trial and regulatory support services
Optimapharm is a contract research organisation providing clinical trial management and observational study services to pharmaceutical, biotech and medical device companies. The company supports trials from Phase I through Phase IV, offering regulatory affairs, medical writing, clinical monitoring, data management,…
European hub for RNAi therapeutics developer
Alnylam UK is the European operational headquarters of Alnylam Pharmaceuticals, the pioneer of RNA interference therapeutics. Based in Maidenhead, the UK office serves as Alnylam's primary base for European commercial operations, medical affairs, and regulatory activities. Alnylam has six approved RNAi medicines on…
Bespoke bio-analysis and biomarker CRO services for drug discovery
Tetrad Discovery is a preclinical contract research organisation providing bespoke bio-analysis services to pharmaceutical and biotechnology sponsors. The company offers tailored pharmacokinetic and pharmacodynamic analysis, biomarker screening across biological sample types, anti-drug antibody determination and…
AI platform integrating biology, chemistry and automation for drug discovery
Recursion is a clinical-stage biotechnology company using AI and robotic wet-lab automation to industrialise small molecule drug discovery. Its platform integrates phenomics, transcriptomics, proteomics and patient data to identify and optimise drug candidates at scale. Following its acquisition of Oxford-based…
AI-driven combinatorial analytics platform for chronic disease biology
PrecisionLife is a computational biology company applying AI-driven combinatorial analytics to complex chronic diseases. Its platform identifies causal biological mechanisms and patient subgroups at a resolution not achievable by conventional genomic methods, enabling novel drug target discovery, patient…
Native mass spectrometry platform for small molecule drug discovery
OMass Therapeutics is a biotechnology company developing small molecule therapeutics against membrane proteins, GPCRs, and intracellular complexes that have historically been difficult to drug. Its proprietary platform combines native mass spectrometry, novel biochemistry, and custom chemistry to interrogate protein…
Integrated bioprocessing technologies, consumables and services for biopharma
Sartorius Stedim Biotech is a global supplier of bioprocessing technologies, filtration systems, single-use solutions and laboratory instruments for the biopharmaceutical industry. Its UK operations span manufacturing, commercial and contract testing functions, including sites in Stonehouse (consumables and single-use…
Clinical-stage oncology biopharma developing the bispecific antibody ivonescimab
Summit Therapeutics is a clinical-stage oncology company with UK research operations originating from VASTox, a University of Oxford spin-out. The company's lead candidate, ivonescimab, is a bispecific antibody targeting PD-1 and VEGF, in-licensed from Akeso and now in multiple global Phase III trials across non-small…
Biologic therapy for osteoarthritis pain
Levicept is a clinical-stage biotechnology company developing a once-monthly biologic treatment for osteoarthritis pain. Its receptor fusion protein is designed to rebalance neurotrophin signalling in affected joints, potentially providing a non-opioid treatment option. The company has completed a Phase II study…
Robotic laboratory workcells and automation integration for life sciences
Flexible Lab Solutions is a laboratory automation company designing and integrating robotic systems for life science research. Its modular workcells connect liquid handlers, microplate stores, imaging readers and other instruments for automated sample preparation, compound handling and high-throughput screening. The…
AI-powered fertility diagnostics and remote patient pathway platform
Enhanced Fertility is a digital health company providing software and at-home testing services for fertility diagnosis and treatment planning. The company's platform supports patients with remote biomarker testing and personalised fertility assessments, and offers clinics an AI-assisted portal for managing…
Bio-based compostable polymers and industrial materials development
Biome Bioplastics is a developer of renewable, biodegradable and compostable polymer materials for industrial applications. It formulates bio-based resins and tailored blends for films, coatings, injection moulding and other conventional plastics processing methods. Its research combines polymer chemistry, materials…
Academic protein informatics and antibody modelling tools
Oxford Protein Informatics Group is a University of Oxford research team led by Professor Charlotte Deane, developing computational methods for protein structures and interactions. Its researchers apply machine learning and bioinformatics to antibody modelling, immunoinformatics, protein engineering and drug…