Synthetic biology companies engineer biological systems to create new products, processes and capabilities across healthcare, agriculture, manufacturing and environmental applications. The field combines biology, engineering and computational design to reprogram living systems.
This category includes companies working on:
Browse 114 UK synthetic biology companies below.
Microbial CRO for natural product discovery and fermentation scale-up
Isomerase is a company providing contract research and development services centred on microbial synthetic biology, with expertise spanning natural product discovery, enzyme engineering, strain bioengineering, and fermentation process development. It serves clients across pharma, biotech, agritech, food and consumer…
Synthetic biology additives for smart, selectively degradable plastics
E.V.A Biosystems is an early-stage industrial biotech developing synthetic biological additives that can be incorporated into conventional plastics during manufacture. The technology uses engineered biological circuits to sense specific environments, such as seawater or landfill, and activate enzymatic degradation at…
Biotech-manufactured botanical extracts and bioactive ingredients for industry
YOHOLIFE is a London-based biotechnology company producing botanical extracts and bioactive ingredients through plant cell culture and synthetic biology techniques. The company integrates in-house research, manufacturing and compliance to develop application-ready ingredients for the cosmetic, nutraceutical and…
Cell-free enzymatic DNA manufacturing for genetic medicines
Touchlight is a contract development and manufacturing organisation producing synthetic DNA for genetic medicine applications using a cell-free enzymatic process. Its linear, covalently closed DNA constructs are free from bacterial sequences and antibiotic resistance genes, offering regulatory and safety advantages…
Carbon nanodot delivery platform for RNA-based crop protection
CDotBio Limited is a biotech developing carbon nanodot technology to improve the delivery and stability of RNA-based biopesticides and other crop inputs. The platform uses ultra-small, sugar-derived nanoparticles to protect RNA cargo from degradation as it transits into plant cells, enabling species-specific targeting…
Precision fermentation platform producing sustainable palm oil alternatives
Sun Bear Biofuture is an industrial biotech company developing a precision fermentation platform to produce sustainable alternatives to palm oil. Using engineered yeast strains and agricultural side streams as feedstock, the company produces oils with functional properties comparable to palm oil, targeting food…
Synthetic biology facility for gene design, engineering and characterisation
The London Biofoundry is a core facility of SynbiCITE, the UK's national Innovation and Knowledge Centre for Engineering Biology, based at Imperial College London's White City Campus. The facility uses advanced robotic systems to provide design, build, test, and learn services for synthetic DNA and engineered…
Synthetic gene promoter platform for biologics and cell and gene therapy
SynGenSys is a synthetic biology company developing proprietary libraries of synthetic gene promoters and signal peptides designed to improve the yield, specificity, and reliability of recombinant protein expression. Its computational platform uses bioinformatics and AI to design novel promoters from first principles,…
Engineered biological systems for selective rare-earth metal recovery
LanthaGen Bio is an industrial biotechnology company developing biological systems to recover rare-earth metals from complex material streams. It combines engineered metal-binding proteins with selective separation processes to capture lanthanides from sources such as electronic waste. Its approach aims to concentrate…
Carbon capture and biomanufacturing using engineered cyanobacteria
CyanoCapture is a company developing a biomanufacturing platform that uses genetically engineered cyanobacteria to sequester carbon dioxide and convert it into high-value products including recombinant proteins and graphite. Its photobioreactor-based system is designed to offer affordable carbon capture for industrial…
Macrophage-based reprogramming of the innate immune system
Ojas Immune develops therapies that reprogramme macrophages, innate immune cells involved in inflammation, tissue repair and disease. Its platforms combine synthetic biology, stem cell engineering and computational modelling. SyntheMacs focuses on engineered macrophage cell therapies, while ReProMacs explores…
Engineering biology commercialisation and biofoundry research support
SynbiCITE is an engineering biology innovation centre hosted by Imperial College London, supporting the translation of synthetic biology research into commercial applications. It connects researchers, start-ups and industry through accelerator programmes, technical expertise and access to the London Biofoundry, which…
AI-designed regulatory DNA sequences to boost biologics manufacturing yields
Genosys Bio is a UK biotechnology company developing AI models that learn the regulatory grammar of DNA to design improved promoter and terminator sequences for biologics manufacturing. Its platform optimises gene expression in CHO cell lines, helping increase protein yields without changing existing cells, processes…
Microbial conversion of waste into sustainable aviation fuel feedstock
Neela Biotech develops microbial processes that convert food, agricultural and forestry waste into fatty acids for sustainable aviation fuel production. Its approach combines AI-guided microbes with anaerobic digestion and is designed to integrate into existing biogas plants rather than require entirely new…